| Literature DB >> 22743150 |
Samuel Joseph Blows1, Richard Morgan, Umeet Dhariwal, Gemma Petts, Frederico Roncaroli.
Abstract
Deafness is a very common problem in older persons. We present a case of metastatic adenocarcinoma of the pancreas with deafness being the patient's only reason for seeking medical attention. The patient had bilateral vestibulocochlear nerve palsies with associated lower motor neurone facial nerve palsies and a bulbar palsy. Magnetic resonance imaging of his brain was unremarkable. It was only on post-mortem histology that tumour infiltrating the leptomeninges was demonstrated. Leptomeningeal metastases are rarely associated with adenocarcinoma of the pancreas. A review of the literature reveals only two other case reports of mestatic pancreatic carcinoma presenting with deafness but both had demonstrable temporal bone lesions on MRI as opposed to the meninges.Entities:
Mesh:
Year: 2012 PMID: 22743150 DOI: 10.1093/ageing/afs085
Source DB: PubMed Journal: Age Ageing ISSN: 0002-0729 Impact factor: 10.668