Literature DB >> 26639554

Mendelian randomization: applications and limitations in epigenetic studies.

Caroline L Relton1, George Davey Smith1.   

Abstract

Entities:  

Keywords:  DNA methylation; SNP; causal inference; epidemiology; epigenetics; mediation

Mesh：

Year:  2015        PMID： 26639554      PMCID： PMC5330409          DOI： 10.2217/epi.15.88

Source DB:  PubMed          Journal:  Epigenomics        ISSN： 1750-192X            Impact factor:   4.778


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  31 in total

Review 1.  DNA methylation in white blood cells: association with risk factors in epidemiologic studies.

Authors:  Mary Beth Terry; Lissette Delgado-Cruzata; Neomi Vin-Raviv; Hui Chen Wu; Regina M Santella
Journal:  Epigenetics       Date:  2011-07-01       Impact factor: 4.528

2.  An integrative genomics approach to infer causal associations between gene expression and disease.

Authors:  Eric E Schadt; John Lamb; Xia Yang; Jun Zhu; Steve Edwards; Debraj Guhathakurta; Solveig K Sieberts; Stephanie Monks; Marc Reitman; Chunsheng Zhang; Pek Yee Lum; Amy Leonardson; Rolf Thieringer; Joseph M Metzger; Liming Yang; John Castle; Haoyuan Zhu; Shera F Kash; Thomas A Drake; Alan Sachs; Aldons J Lusis
Journal:  Nat Genet       Date:  2005-06-19       Impact factor: 38.330

3.  Does greater adiposity increase blood pressure and hypertension risk?: Mendelian randomization using the FTO/MC4R genotype.

Authors:  Nicholas J Timpson; Roger Harbord; George Davey Smith; Jeppe Zacho; Anne Tybjaerg-Hansen; Børge G Nordestgaard
Journal:  Hypertension       Date:  2009-05-26       Impact factor: 10.190

4.  Low-density lipoprotein cholesterol and the risk of cancer: a mendelian randomization study.

Authors:  Marianne Benn; Anne Tybjærg-Hansen; Stefan Stender; Ruth Frikke-Schmidt; Børge G Nordestgaard
Journal:  J Natl Cancer Inst       Date:  2011-02-01       Impact factor: 13.506

5.  Misclassification of the mediator matters when estimating indirect effects.

Authors:  Tony Blakely; Sarah McKenzie; Kristie Carter
Journal:  J Epidemiol Community Health       Date:  2013-03-16       Impact factor: 3.710

Review 6.  Epigenetic epidemiology of cancer.

Authors:  Timothy M Barrow; Karin B Michels
Journal:  Biochem Biophys Res Commun       Date:  2014-08-11       Impact factor: 3.575

Review 7.  Epigenome-wide association studies for common human diseases.

Authors:  Vardhman K Rakyan; Thomas A Down; David J Balding; Stephan Beck
Journal:  Nat Rev Genet       Date:  2011-07-12       Impact factor: 53.242

8.  Prenatal nutrition, epigenetics and schizophrenia risk: can we test causal effects?

Authors:  James B Kirkbride; Ezra Susser; Marija Kundakovic; Jacob K Kresovich; George Davey Smith; Caroline L Relton
Journal:  Epigenomics       Date:  2012-06       Impact factor: 4.778

9.  Tobacco smoking leads to extensive genome-wide changes in DNA methylation.

Authors:  Sonja Zeilinger; Brigitte Kühnel; Norman Klopp; Hansjörg Baurecht; Anja Kleinschmidt; Christian Gieger; Stephan Weidinger; Eva Lattka; Jerzy Adamski; Annette Peters; Konstantin Strauch; Melanie Waldenberger; Thomas Illig
Journal:  PLoS One       Date:  2013-05-17       Impact factor: 3.240

10.  Mendelian randomisation and causal inference in observational epidemiology.

Authors:  Nuala A Sheehan; Vanessa Didelez; Paul R Burton; Martin D Tobin
Journal:  PLoS Med       Date:  2008-08-26       Impact factor: 11.069
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  23 in total

1.  Mendelian Randomization and the Environmental Epigenetics of Health: a Systematic Review.

Authors:  Maria Grau-Perez; Golareh Agha; Yuanjie Pang; Jose D Bermudez; Maria Tellez-Plaza
Journal:  Curr Environ Health Rep       Date:  2019-03

Review 2.  Early Life Exposures and Adult Cancer Risk.

Authors:  Megan A Clarke; Corinne E Joshu
Journal:  Epidemiol Rev       Date:  2017-01-01       Impact factor: 6.222

3.  Causal Modeling in Environmental Health.

Authors:  Marie-Abèle Bind
Journal:  Annu Rev Public Health       Date:  2019-01-11       Impact factor: 21.981

4.  Antipsychotic Medications and DNA Methylation in Schizophrenia and Bipolar Disorder: A Systematic Review.

Authors:  Kyle J Burghardt; Audrey S Khoury; Zaher Msallaty; Zhengping Yi; Berhane Seyoum
Journal:  Pharmacotherapy       Date:  2020-03-09       Impact factor: 4.705

5.  Identification and validation of seven new loci showing differential DNA methylation related to serum lipid profile: an epigenome-wide approach. The REGICOR study.

Authors:  S Sayols-Baixeras; I Subirana; C Lluis-Ganella; F Civeira; J Roquer; A N Do; D Absher; A Cenarro; D Muñoz; C Soriano-Tárraga; J Jiménez-Conde; J M Ordovas; M Senti; S Aslibekyan; J Marrugat; D K Arnett; R Elosua
Journal:  Hum Mol Genet       Date:  2016-10-15       Impact factor: 6.150

Review 6.  How to make DNA methylome wide association studies more powerful.

Authors:  Xinyi Lin; Sheila Barton; Joanna D Holbrook
Journal:  Epigenomics       Date:  2016-04-07       Impact factor: 4.778

7.  Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach.

Authors:  Michael M Mendelson; Riccardo E Marioni; Roby Joehanes; Chunyu Liu; Åsa K Hedman; Stella Aslibekyan; Ellen W Demerath; Weihua Guan; Degui Zhi; Chen Yao; Tianxiao Huan; Christine Willinger; Brian Chen; Paul Courchesne; Michael Multhaup; Marguerite R Irvin; Ariella Cohain; Eric E Schadt; Megan L Grove; Jan Bressler; Kari North; Johan Sundström; Stefan Gustafsson; Sonia Shah; Allan F McRae; Sarah E Harris; Jude Gibson; Paul Redmond; Janie Corley; Lee Murphy; John M Starr; Erica Kleinbrink; Leonard Lipovich; Peter M Visscher; Naomi R Wray; Ronald M Krauss; Daniele Fallin; Andrew Feinberg; Devin M Absher; Myriam Fornage; James S Pankow; Lars Lind; Caroline Fox; Erik Ingelsson; Donna K Arnett; Eric Boerwinkle; Liming Liang; Daniel Levy; Ian J Deary
Journal:  PLoS Med       Date:  2017-01-17       Impact factor: 11.069

8.  Small-Magnitude Effect Sizes in Epigenetic End Points are Important in Children's Environmental Health Studies: The Children's Environmental Health and Disease Prevention Research Center's Epigenetics Working Group.

Authors:  Carrie V Breton; Carmen J Marsit; Elaine Faustman; Kari Nadeau; Jaclyn M Goodrich; Dana C Dolinoy; Julie Herbstman; Nina Holland; Janine M LaSalle; Rebecca Schmidt; Paul Yousefi; Frederica Perera; Bonnie R Joubert; Joseph Wiemels; Michele Taylor; Ivana V Yang; Rui Chen; Kinjal M Hew; Deborah M Hussey Freeland; Rachel Miller; Susan K Murphy
Journal:  Environ Health Perspect       Date:  2017-03-31       Impact factor: 9.031

9.  A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex.

Authors:  Rebecca G Smith; Ehsan Pishva; Gemma Shireby; Adam R Smith; Janou A Y Roubroeks; Eilis Hannon; Gregory Wheildon; Diego Mastroeni; Gilles Gasparoni; Matthias Riemenschneider; Armin Giese; Andrew J Sharp; Leonard Schalkwyk; Vahram Haroutunian; Wolfgang Viechtbauer; Daniel L A van den Hove; Michael Weedon; Danielle Brokaw; Paul T Francis; Alan J Thomas; Seth Love; Kevin Morgan; Jörn Walter; Paul D Coleman; David A Bennett; Philip L De Jager; Jonathan Mill; Katie Lunnon
Journal:  Nat Commun       Date:  2021-06-10       Impact factor: 14.919

Review 10.  Epigenetic dysregulation of brainstem nuclei in the pathogenesis of Alzheimer's disease: looking in the correct place at the right time?

Authors:  A Iatrou; G Kenis; B P F Rutten; K Lunnon; D L A van den Hove
Journal:  Cell Mol Life Sci       Date:  2016-09-14       Impact factor: 9.261
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