Literature DB >> 26639103

Photocleavable Hydrogels for Light-Triggered siRNA Release.

Cong Truc Huynh1, Minh Khanh Nguyen1, Gulen Yesilbag Tonga2, Lionel Longé2, Vincent M Rotello2, Eben Alsberg1.   

Abstract

A photocleavable hydrogel system for on-demand delivery of genetic material is reported. The release of short interfering RNAs can be triggered by the application of UV light without any loss in bioactivity. This approach provides a promising external stimulus-based nucleic acid delivery platform for applications in disease therapeutics and tissue regeneration.
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  UV-controllable release; controlled release; on-demand release; photolabile hydrogels; siRNA

Mesh：

Substances：

Year:  2015        PMID： 26639103      PMCID： PMC4755586          DOI： 10.1002/adhm.201500778

Source DB:  PubMed          Journal:  Adv Healthc Mater        ISSN： 2192-2640            Impact factor:   9.933


  49 in total

1.  Light-controlled release of caged doxorubicin from folate receptor-targeting PAMAM dendrimer nanoconjugate.

Authors:  Seok Ki Choi; Thommey Thomas; Ming-Hsin Li; Alina Kotlyar; Ankur Desai; James R Baker
Journal:  Chem Commun (Camb)       Date:  2010-02-06       Impact factor: 6.222

Review 2.  Delivery vehicles for small interfering RNA in vivo.

Authors:  Antonin R de Fougerolles
Journal:  Hum Gene Ther       Date:  2008-02       Impact factor: 5.695

Review 3.  RNA interference therapy via functionalized scaffolds.

Authors:  Michael Monaghan; Abhay Pandit
Journal:  Adv Drug Deliv Rev       Date:  2011-01-15       Impact factor: 15.470

4.  Direct cytosolic delivery of siRNA using nanoparticle-stabilized nanocapsules.

Authors:  Ying Jiang; Rui Tang; Bradley Duncan; Ziwen Jiang; Bo Yan; Rubul Mout; Vincent M Rotello
Journal:  Angew Chem Int Ed Engl       Date:  2014-11-12       Impact factor: 15.336

5.  Reductively responsive siRNA-conjugated hydrogel nanoparticles for gene silencing.

Authors:  Stuart S Dunn; Shaomin Tian; Steven Blake; Jin Wang; Ashley L Galloway; Andrew Murphy; Patrick D Pohlhaus; Jason P Rolland; Mary E Napier; Joseph M DeSimone
Journal:  J Am Chem Soc       Date:  2012-04-19       Impact factor: 15.419

6.  Patterning of gene expression using new photolabile groups applied to light activated RNAi.

Authors:  Piyush K Jain; Samit Shah; Simon H Friedman
Journal:  J Am Chem Soc       Date:  2010-12-16       Impact factor: 15.419

7.  Spatial control of cell gene expression by siRNA gradients in biodegradable hydrogels.

Authors:  Michael C Hill; Minh K Nguyen; Oju Jeon; Eben Alsberg
Journal:  Adv Healthc Mater       Date:  2014-12-22       Impact factor: 9.933

8.  RNA interference by nanofiber-based siRNA delivery system.

Authors:  Haoqing Cao; Xu Jiang; Chou Chai; Sing Yian Chew
Journal:  J Control Release       Date:  2010-02-06       Impact factor: 9.776

9.  Paramagnetic levitational assembly of hydrogels.

Authors:  Savas Tasoglu; Doga Kavaz; Umut Atakan Gurkan; Sinan Guven; Pu Chen; Reila Zheng; Utkan Demirci
Journal:  Adv Mater       Date:  2012-12-10       Impact factor: 30.849

10.  Photo-selective delivery of model therapeutics from hydrogels.

Authors:  Donald R Griffin; Andrea M Kasko
Journal:  ACS Macro Lett       Date:  2012-11-20       Impact factor: 6.903
View more
  15 in total

Review 1.  Engineered Hydrogels for Local and Sustained Delivery of RNA-Interference Therapies.

Authors:  Leo L Wang; Jason A Burdick
Journal:  Adv Healthc Mater       Date:  2016-12-15       Impact factor: 9.933

2.  Light-triggered RNA release and induction of hMSC osteogenesis via photodegradable, dual-crosslinked hydrogels.

Authors:  Cong Truc Huynh; Minh Khanh Nguyen; Mantas Naris; Gulen Yesilbag Tonga; Vincent M Rotello; Eben Alsberg
Journal:  Nanomedicine (Lond)       Date:  2016-06-01       Impact factor: 5.307

3.  Spatially and Temporally Controlled Hydrogels for Tissue Engineering.

Authors:  Jeroen Leijten; Jungmok Seo; Kan Yue; Grissel Trujillo-de Santiago; Ali Tamayol; Guillermo U Ruiz-Esparza; Su Ryon Shin; Roholah Sharifi; Iman Noshadi; Mario Moisés Álvarez; Yu Shrike Zhang; Ali Khademhosseini
Journal:  Mater Sci Eng R Rep       Date:  2017-07-25       Impact factor: 36.214

Review 4.  Messenger RNA Delivery for Tissue Engineering and Regenerative Medicine Applications.

Authors:  Siddharth Patel; Avathamsa Athirasala; Paula P Menezes; N Ashwanikumar; Ting Zou; Gaurav Sahay; Luiz E Bertassoni
Journal:  Tissue Eng Part A       Date:  2018-06-07       Impact factor: 3.845

5.  Photocrosslinkable, biodegradable hydrogels with controlled cell adhesivity for prolonged siRNA delivery to hMSCs to enhance their osteogenic differentiation.

Authors:  Minh Khanh Nguyen; Alexandra McMillan; Cong Truc Huynh; Daniel S Schapira; Eben Alsberg
Journal:  J Mater Chem B       Date:  2016-12-14       Impact factor: 6.331

Review 6.  Hydrogels and Hydrogel Nanocomposites: Enhancing Healthcare through Human and Environmental Treatment.

Authors:  Angela M Gutierrez; Erin Molly Frazar; Maria Victoria X Klaus; Pranto Paul; J Zach Hilt
Journal:  Adv Healthc Mater       Date:  2021-12-11       Impact factor: 9.933

7.  Light: A Magical Tool for Controlled Drug Delivery.

Authors:  Yu Tao; Hon Fai Chan; Bingyang Shi; Mingqiang Li; Kam W Leong
Journal:  Adv Funct Mater       Date:  2020-09-09       Impact factor: 18.808

Review 8.  Targeting drug delivery with light: A highly focused approach.

Authors:  Teresa L Rapp; Cole A DeForest
Journal:  Adv Drug Deliv Rev       Date:  2021-01-22       Impact factor: 15.470

9.  Hydrogel microspheres for spatiotemporally controlled delivery of RNA and silencing gene expression within scaffold-free tissue engineered constructs.

Authors:  Alexandra McMillan; Minh Khanh Nguyen; Cong Truc Huynh; Samantha M Sarett; Peilin Ge; Melanie Chetverikova; Kien Nguyen; David Grosh; Craig L Duvall; Eben Alsberg
Journal:  Acta Biomater       Date:  2021-01-16       Impact factor: 8.947

10.  Hydrogel-mediated delivery of microRNA-92a inhibitor polyplex nanoparticles induces localized angiogenesis.

Authors:  Fatemeh Radmanesh; Hamid Sadeghi Abandansari; Mohammad Hossein Ghanian; Sara Pahlavan; Fahimeh Varzideh; Saeed Yakhkeshi; Mehdi Alikhani; Sharif Moradi; Thomas Braun; Hossein Baharvand
Journal:  Angiogenesis       Date:  2021-03-19       Impact factor: 10.658
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.