Literature DB >> 26628513

Planning for the Future of Epidemiology in the Era of Big Data and Precision Medicine.

Muin J Khoury.   

Abstract

We live in the era of genomics and big data. Evaluating the impact on health of large-scale biological, social, and environmental data is an emerging challenge in the field of epidemiology. In the past 3 years, major discussions and plans for the future of epidemiology, including with several recommendations for actions to transform the field, have been launched by 2 institutes within the National Institutes of Health. In the present commentary, I briefly explore the themes of these recommendations and their effects on leadership, resources, cohort infrastructure, and training. Ongoing engagement within the epidemiology community is needed to determine how to shape the evolution of the field and what truly matters for changing population health. We also need to assess how to leverage existing epidemiology resources and develop new studies to improve human health. Readers are invited to examine these recommendations, consider others that might be important, and join in the conversation about the future of epidemiology. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US.

Entities:  

Keywords:  big data; epidemiology; funding; genomics; precision medicine; training

Mesh:

Year:  2015        PMID: 26628513      PMCID: PMC4681267          DOI: 10.1093/aje/kwv228

Source DB:  PubMed          Journal:  Am J Epidemiol        ISSN: 0002-9262            Impact factor:   4.897


  15 in total

1.  The role of epidemiology in the era of molecular epidemiology and genomics: Summary of the 2013 AJE-sponsored Society of Epidemiologic Research Symposium.

Authors:  Lewis H Kuller; Michael B Bracken; Shuji Ogino; Ross L Prentice; Russell P Tracy
Journal:  Am J Epidemiol       Date:  2013-10-08       Impact factor: 4.897

2.  An argument for a consequentialist epidemiology.

Authors:  Sandro Galea
Journal:  Am J Epidemiol       Date:  2013-09-10       Impact factor: 4.897

3.  Medicine. Big data meets public health.

Authors:  Muin J Khoury; John P A Ioannidis
Journal:  Science       Date:  2014-11-28       Impact factor: 47.728

4.  A new initiative on precision medicine.

Authors:  Francis S Collins; Harold Varmus
Journal:  N Engl J Med       Date:  2015-01-30       Impact factor: 91.245

5.  Time for a creative transformation of epidemiology in the United States.

Authors:  Michael S Lauer
Journal:  JAMA       Date:  2012-11-07       Impact factor: 56.272

6.  A primer series on -omic technologies for the practice of epidemiology.

Authors:  Muin J Khoury
Journal:  Am J Epidemiol       Date:  2014-06-24       Impact factor: 4.897

Review 7.  Toward a road map for global -omics: a primer on -omic technologies.

Authors:  Steven S Coughlin
Journal:  Am J Epidemiol       Date:  2014-11-18       Impact factor: 4.897

8.  The emergence of translational epidemiology: from scientific discovery to population health impact.

Authors:  Muin J Khoury; Marta Gwinn; John P A Ioannidis
Journal:  Am J Epidemiol       Date:  2010-08-05       Impact factor: 4.897

Review 9.  Design and Analysis for Studying microRNAs in Human Disease: A Primer on -Omic Technologies.

Authors:  Viswam S Nair; Colin C Pritchard; Muneesh Tewari; John P A Ioannidis
Journal:  Am J Epidemiol       Date:  2014-06-24       Impact factor: 4.897

Review 10.  Design and analysis of metabolomics studies in epidemiologic research: a primer on -omic technologies.

Authors:  Ioanna Tzoulaki; Timothy M D Ebbels; Ana Valdes; Paul Elliott; John P A Ioannidis
Journal:  Am J Epidemiol       Date:  2014-06-24       Impact factor: 4.897

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  12 in total

Review 1.  Posttraumatic Stress Disorder and Death From Suicide.

Authors:  Jaimie L Gradus
Journal:  Curr Psychiatry Rep       Date:  2018-09-17       Impact factor: 5.285

2.  Geospatial Approaches to Cancer Control and Population Sciences.

Authors:  Mario Schootman; Scarlett Lin Gomez; Kevin A Henry; Electra D Paskett; Gary L Ellison; April Oh; Stephen H Taplin; Zaria Tatalovich; David A Berrigan
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2017-03-21       Impact factor: 4.254

3.  Creation of a Multicenter Pediatric Inpatient Data Repository Derived from Electronic Health Records.

Authors:  Christoph P Hornik; Andrew M Atz; Catherine Bendel; Francis Chan; Kevin Downes; Robert Grundmeier; Ben Fogel; Debbie Gipson; Matthew Laughon; Michael Miller; Michael Smith; Chad Livingston; Cindy Kluchar; Anne Heath; Chanda Jarrett; Brian McKerlie; Hetalkumar Patel; Christina Hunter
Journal:  Appl Clin Inform       Date:  2019-05-08       Impact factor: 2.342

4.  "Big data" in economic history.

Authors:  Myron P Gutmann; Emily Klancher Merchant; Evan Roberts
Journal:  J Econ Hist       Date:  2018-04-03

5.  The replication crisis in epidemiology: snowball, snow job, or winter solstice?

Authors:  Timothy L Lash; Lindsay J Collin; Miriam E Van Dyke
Journal:  Curr Epidemiol Rep       Date:  2018-04-12

6.  A Structured Approach to Evaluating Life-Course Hypotheses: Moving Beyond Analyses of Exposed Versus Unexposed in the -Omics Context.

Authors:  Yiwen Zhu; Andrew J Simpkin; Matthew J Suderman; Alexandre A Lussier; Esther Walton; Erin C Dunn; Andrew D A C Smith
Journal:  Am J Epidemiol       Date:  2021-06-01       Impact factor: 4.897

Review 7.  The Evolution of Public Health Genomics: Exploring Its Past, Present, and Future.

Authors:  Caron M Molster; Faye L Bowman; Gemma A Bilkey; Angela S Cho; Belinda L Burns; Kristen J Nowak; Hugh J S Dawkins
Journal:  Front Public Health       Date:  2018-09-04

Review 8.  Emerging technologies to measure neighborhood conditions in public health: implications for interventions and next steps.

Authors:  M Schootman; E J Nelson; K Werner; E Shacham; M Elliott; K Ratnapradipa; M Lian; A McVay
Journal:  Int J Health Geogr       Date:  2016-06-23       Impact factor: 3.918

9.  Joint Registration System under the Background of Big Data.

Authors:  Run Tian; Pei Yang; Kun-Zheng Wang
Journal:  Chin Med J (Engl)       Date:  2017-11-05       Impact factor: 2.628

10.  Pharmacological therapy and blood pressure control in primary health care sites in China: data from 254,848 hypertensive patients.

Authors:  Lei Hou; Xiaorong Chen; Bo Chen; Longjian Liu; Xiaohui Sun; Yuewei Zou; Hongjian Liu; Hui Guo; Jian Zhang; Jixiang Ma
Journal:  Clin Epidemiol       Date:  2018-10-11       Impact factor: 4.790

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