Literature DB >> 26628318

Oncologic outcomes after nipple-sparing mastectomy: A single-institution experience.

Jordan D Frey1, Michael Alperovich1, Jennifer Chun Kim2, Deborah M Axelrod2, Richard L Shapiro2, Mihye Choi1, Freya R Schnabel2, Nolan S Karp1, Amber A Guth2.   

Abstract

INTRODUCTION: Long-term oncologic outcomes in nipple-sparing mastectomy (NSM) continue to be defined. Rates of locoregional recurrence for skin-sparing mastectomy (SSM) and NSM in the literature range from 0% to 14.3%. We investigated the outcomes of NSM at our institution.
METHODS: Patients undergoing NSM at our institution from 2006 to 2014 were identified and outcomes were analyzed.
RESULTS: From 2006 to 2014, 319 patients (555 breasts) underwent NSM. One-hundered and fourty-one patients (237 breasts) had long-term follow-up available. Average patient age and BMI were 47.78 and 24.63. Eighty-four percent of patients underwent mastectomy primarily for a therapeutic indication. Average tumor size was 1.50 cm with the most common histologic type being invasive ductal carcinoma (62.7%) followed by DCIS (23.7%). Average patient follow-up was 30.73 months. There was one (0.8%) incidence of ipsilateral chest-wall recurrence. There were 0.37 complications per patient.
CONCLUSIONS: We examined our institutional outcomes with NSM and found a locoregional recurrence rate of 0.8% with no nipple-areolar complex recurrence. This rate is lower than published rates for both NSM and SSM.
© 2015 Wiley Periodicals, Inc.

Entities:  

Keywords:  breast cancer; locoregional recurrence; nipple-sparing mastectomy; oncologic; outcomes; reconstructive

Mesh:

Year:  2015        PMID: 26628318     DOI: 10.1002/jso.24097

Source DB:  PubMed          Journal:  J Surg Oncol        ISSN: 0022-4790            Impact factor:   3.454


  4 in total

1.  Nipple-Sparing Mastectomy is Not Associated with a Delay of Adjuvant Treatment.

Authors:  Emily L Albright; Mary C Schroeder; Kendra Foster; Sonia L Sugg; Lillian M Erdahl; Ronald J Weigel; Ingrid M Lizarraga
Journal:  Ann Surg Oncol       Date:  2018-04-18       Impact factor: 5.344

Review 2.  Pattern of local recurrence after mastectomy and reconstruction in breast cancer patients: a systematic review.

Authors:  Ji Hyeon Joo; Yongkan Ki; Wontaek Kim; Jiho Nam; Donghyun Kim; Jongmoo Park; Hyun Yul Kim; Youn Joo Jung; Ki Seok Choo; Kyung Jin Nam; Su Bong Nam
Journal:  Gland Surg       Date:  2021-06

3.  Non-BRCA1/2 Breast Cancer Susceptibility Genes: A New Frontier with Clinical Consequences for Plastic Surgeons.

Authors:  Jordan D Frey; Ara A Salibian; Freya R Schnabel; Mihye Choi; Nolan S Karp
Journal:  Plast Reconstr Surg Glob Open       Date:  2017-11-20

4.  Mastectomy Flap Thickness and Complications in Nipple-Sparing Mastectomy: Objective Evaluation using Magnetic Resonance Imaging.

Authors:  Jordan D Frey; Ara A Salibian; Mihye Choi; Nolan S Karp
Journal:  Plast Reconstr Surg Glob Open       Date:  2017-08-08
  4 in total

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