| Literature DB >> 26621901 |
Ellen M Bp Reuling1, Tijs S C Jakma1, Johannes Marco Schnater1, Peter E Westerweel2.
Abstract
Spontaneous sternal fracture is a well-known complication of multiple myeloma due to osteolytic bone lesions. The possibility of a multiple myeloma should be thoroughly investigated in patients presenting with a spontaneous sternal fracture. This work up should go beyond protein electrophoresis alone as a monoclonal paraprotein is not always present. In some cases, the myeloma plasma cell clone produces only the free light chain (κ or λ) or may even be non-secretory. The underlying plasma cell dyscrasia is treated with chemotherapy and, if needed, local radiotherapy. However, for patients with a fracture causing persistent pain and physical discomfort, internal fixation may be additionally required. We present a case of a patient who presented with a displaced pathological sternal fracture. She was treated with chemotherapy, radiotherapy and an open reduction and internal fixation with a Locking Compression Plate (LCP). This technique offers a feasible option for rigid fixation of pathological fractures. 2015 BMJ Publishing Group Ltd.Entities:
Mesh:
Year: 2015 PMID: 26621901 PMCID: PMC4680244 DOI: 10.1136/bcr-2015-211498
Source DB: PubMed Journal: BMJ Case Rep ISSN: 1757-790X