Literature DB >> 26621901

Spontaneous sternal fracture due to multiple myeloma requiring extensive surgical repair.

Ellen M Bp Reuling1, Tijs S C Jakma1, Johannes Marco Schnater1, Peter E Westerweel2.   

Abstract

Spontaneous sternal fracture is a well-known complication of multiple myeloma due to osteolytic bone lesions. The possibility of a multiple myeloma should be thoroughly investigated in patients presenting with a spontaneous sternal fracture. This work up should go beyond protein electrophoresis alone as a monoclonal paraprotein is not always present. In some cases, the myeloma plasma cell clone produces only the free light chain (κ or λ) or may even be non-secretory. The underlying plasma cell dyscrasia is treated with chemotherapy and, if needed, local radiotherapy. However, for patients with a fracture causing persistent pain and physical discomfort, internal fixation may be additionally required. We present a case of a patient who presented with a displaced pathological sternal fracture. She was treated with chemotherapy, radiotherapy and an open reduction and internal fixation with a Locking Compression Plate (LCP). This technique offers a feasible option for rigid fixation of pathological fractures. 2015 BMJ Publishing Group Ltd.

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Mesh:

Year:  2015        PMID: 26621901      PMCID: PMC4680244          DOI: 10.1136/bcr-2015-211498

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  21 in total

1.  Letter: IgA myeloma and sternal fracture.

Authors:  I P Law; C Jones
Journal:  JAMA       Date:  1975-08-18       Impact factor: 56.272

Review 2.  Serum free light chain analysis.

Authors:  Matthew S Davids; Mandakolathur R Murali; David J Kuter
Journal:  Am J Hematol       Date:  2010-10       Impact factor: 10.047

3.  Stability provided by the sternum and rib cage in the thoracic spine.

Authors:  Robert Watkins; Robert Watkins; Lytton Williams; Scott Ahlbrand; Ryan Garcia; Ara Karamanian; Lorra Sharp; Chuong Vo; Thomas Hedman
Journal:  Spine (Phila Pa 1976)       Date:  2005-06-01       Impact factor: 3.468

Review 4.  Multiple myeloma.

Authors:  Robert A Kyle; S Vincent Rajkumar
Journal:  N Engl J Med       Date:  2004-10-28       Impact factor: 91.245

5.  Sternal plating for the treatment of sternal nonunion.

Authors:  S C Hendrickson; K E Koger; C J Morea; R L Aponte; P K Smith; L S Levin
Journal:  Ann Thorac Surg       Date:  1996-08       Impact factor: 4.330

6.  Correlation of radiological manifestations of multiple myeloma with immunoglobulin abnormalities and prognosis.

Authors:  B M Gompels; M L Votaw; W Martel
Journal:  Radiology       Date:  1972-09       Impact factor: 11.105

Review 7.  Fixation of sternal fractures: a systematic review.

Authors:  Andrew Harston; Craig Roberts
Journal:  J Trauma       Date:  2011-12

8.  International staging system for multiple myeloma.

Authors:  Philip R Greipp; Jesus San Miguel; Brian G M Durie; John J Crowley; Bart Barlogie; Joan Bladé; Mario Boccadoro; J Anthony Child; Herve Avet-Loiseau; Jean-Luc Harousseau; Robert A Kyle; Juan J Lahuerta; Heinz Ludwig; Gareth Morgan; Raymond Powles; Kazuyuki Shimizu; Chaim Shustik; Pieter Sonneveld; Patrizia Tosi; Ingemar Turesson; Jan Westin
Journal:  J Clin Oncol       Date:  2005-04-04       Impact factor: 44.544

9.  Incidence of hematologic malignancies in Europe by morphologic subtype: results of the HAEMACARE project.

Authors:  Milena Sant; Claudia Allemani; Carmen Tereanu; Roberta De Angelis; Riccardo Capocaccia; Otto Visser; Rafael Marcos-Gragera; Marc Maynadié; Arianna Simonetti; Jean-Michel Lutz; Franco Berrino
Journal:  Blood       Date:  2010-07-27       Impact factor: 22.113

10.  Surgical fixation of sternal fractures: preoperative planning and a safe surgical technique using locked titanium plates and depth limited drilling.

Authors:  Stefan Schulz-Drost; Pascal Oppel; Sina Grupp; Sonja Schmitt; Roman Th Carbon; Andreas Mauerer; Friedrich F Hennig; Thomas Buder
Journal:  J Vis Exp       Date:  2015-01-05       Impact factor: 1.355

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