Amarnath Singh1, Kesavachandran Chandrasekharan Nair2, Ritul Kamal3, Vipin Bihari3, Manoj Kumar Gupta4, Mohana Krishna Reddy Mudiam4, Gubbala Naga Venkata Satyanarayana4, Abhay Raj5, Izharul Haq5, Nishi Kumar Shukla6, Altaf Husain Khan6, Anup Kumar Srivastava7. 1. Epidemiology Division, CSIR-Indian Institute of Toxicology Research, Lucknow, India; Dept. of Biochemistry, Babu Banarasi Das University, BBD City, Faizabad Road, Lucknow, India. 2. Epidemiology Division, CSIR-Indian Institute of Toxicology Research, Lucknow, India. Electronic address: ckesavachandran@gmail.com. 3. Epidemiology Division, CSIR-Indian Institute of Toxicology Research, Lucknow, India. 4. Analytical Chemistry Division, CSIR-Indian Institute of Toxicology Research, Lucknow, India. 5. Environmental Microbiology Division, CSIR-Indian Institute of Toxicology Research, Lucknow, India. 6. Environmental Monitoring Division, CSIR-Indian Institute of Toxicology Research, Lucknow, India. 7. Dept. of Community Medicine, Hind Institute of Medical Sciences, Near Canal, Safedabad, Barabanki Road, Lucknow, India.
Abstract
BACKGROUND: Indoor air pollution is associated with decreased pulmonary function but the relative impact of pollution from kitchen sources on health risks in kitchen workers is not well-known or studied. A study was conducted to measure the kitchen indoor air quality including PAHs estimation and risk assessment based on reported PAHs in indoor air in a central kitchen at North India. METHODS: A cross sectional study was undertaken to assess the lung function status using spirometer and urinary PAH metabolite measurements using GC-MS/MS among 94 male kitchen workers and their corresponding controls. Assessment of the indoor air quality levels was evaluated using standard methods. RESULTS: All the indoor air pollutants were within the recommended guidelines except CO, TVOC and PAH emission in the kitchen. Incremental life time cancer risk (ICLR) based on indoor air PAH measurements indicates potential for carcinogenic risk. Significant lung function decline was observed among kitchen workers as compared to controls after adjusting for smoking habits. Urinary PAH metabolites were detected in kitchen workers and measured concentrations were comparatively higher than control subjects. CONCLUSION: The decline in lung functions after adjustment for confounders and detection of urinary PAH metabolites in kitchen workers can be associated with higher concentrations of PAHs, CO and TVOCs in kitchen indoor air.
BACKGROUND: Indoor air pollution is associated with decreased pulmonary function but the relative impact of pollution from kitchen sources on health risks in kitchen workers is not well-known or studied. A study was conducted to measure the kitchen indoor air quality including PAHs estimation and risk assessment based on reported PAHs in indoor air in a central kitchen at North India. METHODS: A cross sectional study was undertaken to assess the lung function status using spirometer and urinary PAH metabolite measurements using GC-MS/MS among 94 male kitchen workers and their corresponding controls. Assessment of the indoor air quality levels was evaluated using standard methods. RESULTS: All the indoor air pollutants were within the recommended guidelines except CO, TVOC and PAH emission in the kitchen. Incremental life time cancer risk (ICLR) based on indoor air PAH measurements indicates potential for carcinogenic risk. Significant lung function decline was observed among kitchen workers as compared to controls after adjusting for smoking habits. Urinary PAH metabolites were detected in kitchen workers and measured concentrations were comparatively higher than control subjects. CONCLUSION: The decline in lung functions after adjustment for confounders and detection of urinary PAH metabolites in kitchen workers can be associated with higher concentrations of PAHs, CO and TVOCs in kitchen indoor air.
Authors: Marta Oliveira; Sílvia Capelas; Cristina Delerue-Matos; Simone Morais Journal: Int J Environ Res Public Health Date: 2020-12-30 Impact factor: 3.390
Authors: Araliya M Senerat; Sheila M Manemann; Nicholas S Clements; Robert D Brook; Leslie C Hassett; Véronique L Roger Journal: J Clin Transl Sci Date: 2020-09-04