Literature DB >> 26615908

Semisynthetic UbH2A reveals different activities of deubiquitinases and inhibitory effects of H2A K119 ubiquitination on H3K36 methylation in mononucleosomes.

Xiaobao Bi1, Renliang Yang, Xiaoyu Feng, Daniela Rhodes, Chuan-Fa Liu.   

Abstract

Using a genetically incorporated azidonorleucine for ubiquitin installation, we prepared multi-milligram quantities of H2AK119ub (ubH2A). With a native isopeptide linkage, the synthetic ubH2A was used to study the activity of deubiquitinases and crosstalk between H2A ubiquitination and H3K36 methylation in the context of chemically defined mononucleosomes.

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Year:  2015        PMID： 26615908     DOI： 10.1039/c5ob02323h

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  7 in total

Review 1.  Chemoenzymatic Semisynthesis of Proteins.

Authors:  Robert E Thompson; Tom W Muir
Journal:  Chem Rev       Date:  2019-11-27       Impact factor: 60.622

Review 2.  Studies of biochemical crosstalk in chromatin with semisynthetic histones.

Authors:  Calvin Jon Antolin Leonen; Esha Upadhyay; Champak Chatterjee
Journal:  Curr Opin Chem Biol       Date:  2018-02-27       Impact factor: 8.822

3.  Histone Modifications, Internucleosome Dynamics, and DNA Stresses: How They Cooperate to "Functionalize" Nucleosomes.

Authors:  Wladyslaw A Krajewski
Journal:  Front Genet       Date:  2022-04-28       Impact factor: 4.772

4.  Role of remodeling and spacing factor 1 in histone H2A ubiquitination-mediated gene silencing.

Authors:  Zhuo Zhang; Amanda E Jones; Wei Wu; Jinman Kim; Yue Kang; Xiaobao Bi; Yue Gu; Ivan K Popov; Matthew B Renfrow; Marina N Vassylyeva; Dmitry G Vassylyev; Keith E Giles; Dongquan Chen; Ashwath Kumar; Yuhong Fan; Yufeng Tong; Chuan-Fa Liu; Woojin An; Chenbei Chang; Jianjun Luo; Louise T Chow; Hengbin Wang
Journal:  Proc Natl Acad Sci U S A       Date:  2017-08-30       Impact factor: 11.205

Review 5.  The Bre1/Rad6 machinery: writing the central histone ubiquitin mark on H2B and beyond.

Authors:  Zhi-Heng Deng; Hua-Song Ai; Cheng-Piao Lu; Jia-Bin Li
Journal:  Chromosome Res       Date:  2020-09-07       Impact factor: 5.239

Review 6.  Total Chemical Synthesis of Modified Histones.

Authors:  Yun-Kun Qi; Hua-Song Ai; Yi-Ming Li; Baihui Yan
Journal:  Front Chem       Date:  2018-02-06       Impact factor: 5.221

7.  Changes in γH2AX and H4K16ac levels are involved in the biochemical response to a competitive soccer match in adolescent players.

Authors:  Katarzyna Kozioł; Jacek Zebrowski; Gabriela Betlej; Ewelina Bator; Wojciech Czarny; Wojciech Bajorek; Bartłomiej Czarnota; Robert Czaja; Paweł Król; Aleksandra Kwiatkowska
Journal:  Sci Rep       Date:  2020-09-02       Impact factor: 4.379
  7 in total

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