| Literature DB >> 26610503 |
Shengyun Liang1,2, Yunkun Ning3, Huiqi Li4, Lei Wang5, Zhanyong Mei6, Yingnan Ma7, Guoru Zhao8.
Abstract
The aging process may lead to the degradation of lower extremity function in the elderly population, which can restrict their daily quality of life and gradually increase the fall risk. We aimed to determine whether objective measures of physical function could predict subsequent falls. Ground reaction force (GRF) data, which was quantified by sample entropy, was collected by foot force sensors. Thirty eight subjects (23 fallers and 15 non-fallers) participated in functional movement tests, including walking and sit-to-stand (STS). A feature selection algorithm was used to select relevant features to classify the elderly into two groups: at risk and not at risk of falling down, for three KNN-based classifiers: local mean-based k-nearest neighbor (LMKNN), pseudo nearest neighbor (PNN), local mean pseudo nearest neighbor (LMPNN) classification. We compared classification performances, and achieved the best results with LMPNN, with sensitivity, specificity and accuracy all 100%. Moreover, a subset of GRFs was significantly different between the two groups via Wilcoxon rank sum test, which is compatible with the classification results. This method could potentially be used by non-experts to monitor balance and the risk of falling down in the elderly population.Entities:
Keywords: KNN-based classifier; fall prediction; feature selection; gait and balance; ground reaction force; lower limb extremity; sample entropy
Mesh:
Year: 2015 PMID: 26610503 PMCID: PMC4701339 DOI: 10.3390/s151129393
Source DB: PubMed Journal: Sensors (Basel) ISSN: 1424-8220 Impact factor: 3.576
Figure 1GRF components: Fx Fy, and Fz on the multi-axis force platform. Fx Fy, and Fz represent medial-lateral, anterior-posterior and superior-inferior GRF for foot during walking, respectively.
Figure 2GRF on the force plate during STS movement. At the beginning of STS movement, the person keep on stand (t1). The time from stand to sit on t2, from sit to stand on t4. The curves for faller are smoother than the non-faller, with lower peak.
The abbreviation of considered physical features.
| No. | The Abbreviated Features | The Meaning of Features |
|---|---|---|
| 1 | L_ML_F | Medial-lateral GRF for left foot during walking |
| 2 | L_AP_F | Anterior-posterior GRF for left foot during walking |
| 3 | L_SI_F | Superior-inferior GRF for left foot during walking |
| 4 | R_ML_F | Medial-lateral GRF for right foot during walking |
| 5 | R-AP_F | Anterior-posterior GRF for right foot during walking |
| 6 | R_SI_F | Superior-inferior GRF for right foot during walking |
| 7 | L_V_F | Vertical GRF for left foot during STS |
| 8 | R_V_F | Vertical GRF for right foot during STS |
Characteristics of the participants in both groups. Values are shown as MEAN ± SD (standard deviation) in two groups; p-values are based on t-tests comparing continuous data or chi-square tests comparing categorical data.
| Characteristic | Faller (n = 23) | Non-Faller (n = 15) | |
|---|---|---|---|
| Age (years) | 72.29 ± 4.98; 65–84 | 69.93 ± 4.51; 65–78 | 0.12 |
| Gender (%men) | 42.85% | 45.83% | 0.99 |
| Weight (kg) | 65.92 ± 10.17 | 58.33 ± 18.18 | 0.16 |
| Number of medications | 1.45 ± 0.97 | 1.5 ± 1.09 | 0.91 |
| Number of diseases | 1.08 ± 1.34 | 0.86 ± 1.1 | 0.57 |
The selected features and relevant classification performance for the three classification algorithms.
| Algorithm | Select Features | Accuracy Rate | Sensitivity Rate | Specificity Rate |
|---|---|---|---|---|
| LMPNN | L_SI_F, R_ML_F, R_AP_F, L_V_F (k = 3) | 100% | 100% | 100% |
| PNN | L_SI_F, R_ML_F, R_AP_F, L_V_F, R_V_F (k = 1/2/3/4) | 92.11% | 78.57% | 100% |
| LMKNN | L_SI_F, R_ML_F, R_AP_F, L_V_F (k = 2) | 94.74% | 85.71% | 100% |
Figure 3The classification rates of LMPNN, PNN, and LMKNN on real data via different k nearest neighbor methods.
The comparison of fallers with non-fallers using the Wilcoxon rank sum test on sample entropies concerning eight features. Values are shown as MEAN ± SD (Standard deviation) in two groups; significant results are indicated with an asterisk (*).
| The Abbreviated Features | Faller | Non-Faller | |
|---|---|---|---|
| L_ML_F | 0.5586 ± 0.1389 | 0.6246 ± 0.1858 | 0.2092 |
| L_AP_F | 0.4496 ± 0.0915 | 0.4835 ± 0.0421 | 0.1341 |
| L_SI_F | 0.2574 ± 0.1655 | 0.2819 ± 0.0690 | 0.0586 * |
| R_ML_F | 0.5700 ± 0.1172 | 0.5826 ± 0.1963 | 0.09879 * |
| R_AP_F | 0.4661 ± 0.0986 | 0.5116 ± 0.0574 | 0.0329 * |
| R_SI_F | 0.2996 ± 0.1485 | 0.3187 ± 0.1144 | 0.3254 |
| L_V_F | 0.0852 ± 0.0297 | 0.1110 ± 0.0313 | 0.0097 * |
| R_V_F | 0.1003 ± 0.0402 | 0.1339 ± 0.0340 | 0.0081 * |
Spearman correlation coefficients among the select features. Significant results are indicated with an asterisk (*).
| L_SI_F | R_ML_F | R_AP_F | L_V_F | R_V_F | ||
|---|---|---|---|---|---|---|
| L_SI_F | r | 1 | 0.493 * | 0.361 * | 0.165 | 0.315 |
| -- | 0.002 | 0.026 | 0.323 | 0.054 | ||
| R_ML_F | r | 0.493 * | 1 | 0.121 | 0.297 | 0.188 |
| 0.002 | -- | 0.469 | 0.070 | 0.258 | ||
| R_AP_F | r | 0.361 * | 0.121 | 1 | 0.188 | 0.205 |
| 0.026 | 0.469 | -- | 0.258 | 0.217 | ||
| L_V_F | r | 0.165 | 0.297 | 0.188 | 1 | 0.547 * |
| 0.323 | 0.070 | 0.258 | -- | 0.000 | ||
| R_V_F | r | 0.315 | 0.188 | 0.205 | 0.547 * | 1 |
| 0.054 | 0.258 | 0.217 | 0.000 | -- |