Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Origin and Functional Evolution of the Cdc48/p97/VCP AAA+ Protein Unfolding and Remodeling Machine.

Literature DB >> 26608813

Origin and Functional Evolution of the Cdc48/p97/VCP AAA+ Protein Unfolding and Remodeling Machine.

Abstract

The AAA+ Cdc48 ATPase (alias p97 or VCP) is a key player in multiple ubiquitin-dependent cell signaling, degradation, and quality control pathways. Central to these broad biological functions is the ability of Cdc48 to interact with a large number of adaptor proteins and to remodel macromolecular proteins and their complexes. Different models have been proposed to explain how Cdc48 might couple ATP hydrolysis to forcible unfolding, dissociation, or remodeling of cellular clients. In this review, we provide an overview of possible mechanisms for substrate unfolding/remodeling by this conserved and essential AAA+ protein machine and their adaption and possible biological function throughout evolution.

Entities: Chemical Disease Gene Mutation Species

Keywords: AAA+ machine; human disease; protein remodeling

Mesh：

Substances：

Year: 2015 PMID： 26608813 PMCID： PMC4860136 DOI： 10.1016/j.jmb.2015.11.015

Source DB: PubMed Journal: J Mol Biol ISSN： 0022-2836 Impact factor: 5.469

107 in total

1. Spring-loaded unraveling of a single SNARE complex by NSF in one round of ATP turnover.

Authors: Je-Kyung Ryu; Duyoung Min; Sang-Hyun Rah; Soo Jin Kim; Yongsoo Park; Haesoo Kim; Changbong Hyeon; Ho Min Kim; Reinhard Jahn; Tae-Young Yoon
Journal: Science Date: 2015-03-27 Impact factor: 47.728

2. Architecture and assembly of the archaeal Cdc48*20S proteasome.

Authors: Dominik Barthelme; James Z Chen; Jonathan Grabenstatter; Tania A Baker; Robert T Sauer
Journal: Proc Natl Acad Sci U S A Date: 2014-04-07 Impact factor: 11.205

3. Valosin-containing protein, VCP, is a ubiquitous clathrin-binding protein.

Authors: I T Pleasure; M M Black; J H Keen
Journal: Nature Date: 1993-09-30 Impact factor: 49.962

4. Stochastic but highly coordinated protein unfolding and translocation by the ClpXP proteolytic machine.

Authors: Juan Carlos Cordova; Adrian O Olivares; Yongdae Shin; Benjamin M Stinson; Stephane Calmat; Karl R Schmitz; Marie-Eve Aubin-Tam; Tania A Baker; Matthew J Lang; Robert T Sauer
Journal: Cell Date: 2014-07-31 Impact factor: 41.582

5. Use of a cDNA clone to identify a supposed precursor protein containing valosin.

Authors: K J Koller; M J Brownstein
Journal: Nature Date: 1987 Feb 5-11 Impact factor: 49.962

6. Structural and mechanistic insights into the arginine/lysine-rich peptide motifs that interact with P97/VCP.

Authors: Shuai Liu; Qing-Shan Fu; Jian Zhao; Hong-Yu Hu
Journal: Biochim Biophys Acta Date: 2013-10-04

7. An abundant and ubiquitous homo-oligomeric ring-shaped ATPase particle related to the putative vesicle fusion proteins Sec18p and NSF.

Authors: J M Peters; M J Walsh; W W Franke
Journal: EMBO J Date: 1990-06 Impact factor: 11.598

8. VCP, the mammalian homolog of cdc48, is tyrosine phosphorylated in response to T cell antigen receptor activation.

Authors: M Egerton; O R Ashe; D Chen; B J Druker; W H Burgess; L E Samelson
Journal: EMBO J Date: 1992-10 Impact factor: 11.598

9. Yeast cell cycle protein CDC48p shows full-length homology to the mammalian protein VCP and is a member of a protein family involved in secretion, peroxisome formation, and gene expression.

Authors: K U Fröhlich; H W Fries; M Rüdiger; R Erdmann; D Botstein; D Mecke
Journal: J Cell Biol Date: 1991-08 Impact factor: 10.539

10. Inter-ring rotations of AAA ATPase p97 revealed by electron cryomicroscopy.

Authors: Heidi O Yeung; Andreas Förster; Cecilia Bebeacua; Hajime Niwa; Caroline Ewens; Ciarán McKeown; Xiaodong Zhang; Paul S Freemont
Journal: Open Biol Date: 2014-03-05 Impact factor: 6.411

23 in total

1. Structural Analysis Reveals Features of Ribosome Assembly Factor Nsa1/WDR74 Important for Localization and Interaction with Rix7/NVL2.

Authors: Yu-Hua Lo; Erin M Romes; Monica C Pillon; Mack Sobhany; Robin E Stanley
Journal: Structure Date: 2017-04-13 Impact factor: 5.006

Review 2. Recent advances in IAP-based PROTACs (SNIPERs) as potential therapeutic agents.

Authors: Chao Wang; Yujing Zhang; Lingyu Shi; Shanbo Yang; Jing Chang; Yingjie Zhong; Qian Li; Dongming Xing
Journal: J Enzyme Inhib Med Chem Date: 2022-12 Impact factor: 5.756

3. PUX10 Is a CDC48A Adaptor Protein That Regulates the Extraction of Ubiquitinated Oleosins from Seed Lipid Droplets in Arabidopsis.

Authors: Carine Deruyffelaere; Zita Purkrtova; Isabelle Bouchez; Boris Collet; Jean-Luc Cacas; Thierry Chardot; Jean-Luc Gallois; Sabine D'Andrea
Journal: Plant Cell Date: 2018-08-07 Impact factor: 11.277

4. 2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition.

Authors: Soojay Banerjee; Alberto Bartesaghi; Alan Merk; Prashant Rao; Stacie L Bulfer; Yongzhao Yan; Neal Green; Barbara Mroczkowski; R Jeffrey Neitz; Peter Wipf; Veronica Falconieri; Raymond J Deshaies; Jacqueline L S Milne; Donna Huryn; Michelle Arkin; Sriram Subramaniam
Journal: Science Date: 2016-01-28 Impact factor: 47.728

5. Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation.

Authors: William A McEwan; Benjamin Falcon; Marina Vaysburd; Dean Clift; Adrian L Oblak; Bernardino Ghetti; Michel Goedert; Leo C James
Journal: Proc Natl Acad Sci U S A Date: 2017-01-03 Impact factor: 11.205

Review 6. Mechanisms of substrate recognition by the 26S proteasome.

Authors: Caroline Davis; Brian Logan Spaller; Andreas Matouschek
Journal: Curr Opin Struct Biol Date: 2020-12-06 Impact factor: 6.809

7. Analysis of Zika virus capsid-Aedes aegypti mosquito interactome reveals pro-viral host factors critical for establishing infection.

Authors: Rommel J Gestuveo; Jamie Royle; Claire L Donald; Douglas J Lamont; Edward C Hutchinson; Andres Merits; Alain Kohl; Margus Varjak
Journal: Nat Commun Date: 2021-05-13 Impact factor: 14.919