Literature DB >> 26604636

MicroRNA in inflammatory bowel disease: Translational research and clinical implication.

Kurt Fisher1, Jingmei Lin1.   

Abstract

Idiopathic inflammatory bowel disease (IBD) predominantly includes ulcerative colitis and Crohn's disease. The pathogenesis of IBD is complex and not completely understood. MicroRNAs belong to a class of noncoding small RNAs that post-transcriptionally regulate gene expression. Unique microRNA expression profiles have been explored in IBD. In this review, we focus on the unique microRNA expression pattern in both tissue and peripheral blood from IBD patients and emphasize the potential diagnostic and therapeutic applications. The discovery of microRNAs has contributed to our understanding of IBD pathogenesis and might lead to clinical advance in new therapeutics.

Entities:  

Keywords:  Crohn’s disease; Gene expression; Inflammatory bowel disease; MicroRNA; Pathogenesis; Ulcerative colitis

Mesh：

Substances：

Year:  2015        PMID： 26604636      PMCID： PMC4649112          DOI： 10.3748/wjg.v21.i43.12274

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN： 1007-9327            Impact factor:   5.742


  76 in total

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Review 2.  Inflammatory bowel disease--environmental modification and genetic determinants.

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Journal:  Pediatr Clin North Am       Date:  2006-08       Impact factor: 3.278

3.  The risk of colorectal cancer in ulcerative colitis: a meta-analysis.

Authors:  J A Eaden; K R Abrams; J F Mayberry
Journal:  Gut       Date:  2001-04       Impact factor: 23.059

4.  Identification of microRNAs associated with ileal and colonic Crohn's disease.

Authors:  Feng Wu; Simin Zhang; Themistocles Dassopoulos; Mary L Harris; Theodore M Bayless; Stephen J Meltzer; Steven R Brant; John H Kwon
Journal:  Inflamm Bowel Dis       Date:  2010-10       Impact factor: 5.325

5.  Circulating microRNA is a biomarker of pediatric Crohn disease.

Authors:  Adam M Zahm; Meena Thayu; Nicholas J Hand; Amber Horner; Mary B Leonard; Joshua R Friedman
Journal:  J Pediatr Gastroenterol Nutr       Date:  2011-07       Impact factor: 2.839

6.  Inflammatory gene signature in ulcerative colitis with cDNA macroarray analysis.

Authors:  S Okahara; Y Arimura; T Yabana; K Kobayashi; A Gotoh; S Motoya; A Imamura; T Endo; K Imai
Journal:  Aliment Pharmacol Ther       Date:  2005-05-01       Impact factor: 8.171

7.  Role of miR-150-targeting c-Myb in colonic epithelial disruption during dextran sulphate sodium-induced murine experimental colitis and human ulcerative colitis.

Authors:  Zhen Bian; Limin Li; Jinglong Cui; Hongjie Zhang; Yuan Liu; Chen-Yu Zhang; Ke Zen
Journal:  J Pathol       Date:  2011-05-18       Impact factor: 7.996

8.  Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis.

Authors:  Matthew Rutter; Brian Saunders; Kay Wilkinson; Steve Rumbles; Gillian Schofield; Michael Kamm; Christopher Williams; Ashley Price; Ian Talbot; Alastair Forbes
Journal:  Gastroenterology       Date:  2004-02       Impact factor: 22.682

Review 9.  Modulation of miRNA activity in human cancer: a new paradigm for cancer gene therapy?

Authors:  A W Tong; J Nemunaitis
Journal:  Cancer Gene Ther       Date:  2008-03-28       Impact factor: 5.987

10.  Two-stage genome-wide methylation profiling in childhood-onset Crohn's Disease implicates epigenetic alterations at the VMP1/MIR21 and HLA loci.

Authors:  Alex T Adams; Nicholas A Kennedy; Richard Hansen; Nicholas T Ventham; Kate R OʼLeary; Hazel E Drummond; Colin L Noble; Emad El-Omar; Richard K Russell; David C Wilson; Elaine R Nimmo; Georgina L Hold; Jack Satsangi
Journal:  Inflamm Bowel Dis       Date:  2014-10       Impact factor: 7.290
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  19 in total

1.  Identification of suitable reference microRNA for qPCR analysis in pediatric inflammatory bowel disease.

Authors:  Christie Buonpane; Guillermo Ares; Beshoy Benyamen; Carrie Yuan; Catherine J Hunter
Journal:  Physiol Genomics       Date:  2019-04-12       Impact factor: 3.107

Review 2.  MicroRNA in gastrointestinal cell signalling.

Authors:  Priyanka Mishra; Divya Singh; Lilly Ganju; Bhuvnesh Kumar
Journal:  Inflammopharmacology       Date:  2017-11-06       Impact factor: 4.473

Review 3.  Recent Advances in the Etiopathogenesis of Inflammatory Bowel Disease: The Role of Omics.

Authors:  Eleni Stylianou
Journal:  Mol Diagn Ther       Date:  2018-02       Impact factor: 4.074

4.  MicroRNA-520b affects the proliferation of human glioblastoma cells by directly targeting cyclin D1.

Authors:  Xuchang Liu; Fachen Wang; Lin Tian; Tongxin Wang; Wei Zhang; Ben Li; Yun-An Bai
Journal:  Tumour Biol       Date:  2015-12-23

5.  Identification of microRNA-16-5p and microRNA-21-5p in feces as potential noninvasive biomarkers for inflammatory bowel disease.

Authors:  Rui Zhou; Peishan Qiu; Haizhou Wang; Huijie Yang; Xueying Yang; Mingliang Ye; Fan Wang; Qiu Zhao
Journal:  Aging (Albany NY)       Date:  2021-02-01       Impact factor: 5.682

6.  Andrographolide Suppresses Pyroptosis in Mycobacterium tuberculosis-Infected Macrophages via the microRNA-155/Nrf2 Axis.

Authors:  Yan Fu; Jingjing Shen; Fanglin Liu; Hemin Zhang; Yuejuan Zheng; Xin Jiang
Journal:  Oxid Med Cell Longev       Date:  2022-04-28       Impact factor: 7.310

7.  Doxycycline, metronidazole and isotretinoin: Do they modify microRNA/mRNA expression profiles and function in murine T-cells?

Authors:  Eugenia Becker; Susan Bengs; Sirisha Aluri; Lennart Opitz; Kirstin Atrott; Claudia Stanzel; Pedro A Ruiz Castro; Gerhard Rogler; Isabelle Frey-Wagner
Journal:  Sci Rep       Date:  2016-11-17       Impact factor: 4.379

8.  MicroRNA exhibit altered expression in the inflamed colonic mucosa of ulcerative colitis patients.

Authors:  Swati Valmiki; Vineet Ahuja; Jaishree Paul
Journal:  World J Gastroenterol       Date:  2017-08-07       Impact factor: 5.742

9.  MicroRNA-155 promotes the pathogenesis of experimental colitis by repressing SHIP-1 expression.

Authors:  Zhan-Jun Lu; Jian-Jiong Wu; Wei-Liang Jiang; Jun-Hua Xiao; Kai-Zhong Tao; Lei Ma; Ping Zheng; Rong Wan; Xing-Peng Wang
Journal:  World J Gastroenterol       Date:  2017-02-14       Impact factor: 5.742

10.  In silico identification of microRNAs predicted to regulate N-myristoyltransferase and Methionine Aminopeptidase 2 functions in cancer and infectious diseases.

Authors:  Ranjit Chauhan; David Datzkiw; Shailly Varma Shrivastav; Anuraag Shrivastav
Journal:  PLoS One       Date:  2018-03-26       Impact factor: 3.240
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