Literature DB >> 26600102

Genetics of Sleep Disorders.

Philip R Gehrman1, Brendan T Keenan2, Enda M Byrne3, Allan I Pack4.   

Abstract

Sleep disorders are, in part, attributable to genetic variability across individuals. There has been considerable progress in understanding the role of genes for some sleep disorders, such as the identification of a human leukocyte antigen gene for narcolepsy. For other sleep disorders, such as insomnia, little work has been done. Optimizing phenotyping strategies is critical, as is the case for sleep apnea, for which intermediate traits such as obesity and craniofacial features may prove to be more tractable for genetic studies. Rapid advances in genotyping and statistical genetics are likely to lead to greater discoveries in the near future. Published by Elsevier Inc.

Entities:  

Keywords:  Genetics; Insomnia; Narcolepsy; Restless legs syndrome; Sleep apnea; Sleep disorder

Mesh：

Year:  2015        PMID： 26600102     DOI： 10.1016/j.psc.2015.07.004

Source DB:  PubMed          Journal:  Psychiatr Clin North Am        ISSN： 0193-953X


  10 in total

1.  Current child, but not maternal, snoring is bi-directionally related to adiposity and cardiometabolic risk markers: A cross-sectional and a prospective cohort analysis.

Authors:  Olivia M Farr; Sheryl L Rifas-Shiman; Emily Oken; Elsie M Taveras; Christos S Mantzoros
Journal:  Metabolism       Date:  2017-06-29       Impact factor: 8.694

Review 2.  Pleiotropic genetic effects influencing sleep and neurological disorders.

Authors:  Olivia J Veatch; Brendan T Keenan; Philip R Gehrman; Beth A Malow; Allan I Pack
Journal:  Lancet Neurol       Date:  2017-02       Impact factor: 44.182

3.  High-throughput sleep phenotyping produces robust and heritable traits in Diversity Outbred mice and their founder strains.

Authors:  Brendan T Keenan; Raymond J Galante; Jie Lian; Petr Simecek; Daniel M Gatti; Lin Zhang; Diane C Lim; Karen L Svenson; Gary A Churchill; Allan I Pack
Journal:  Sleep       Date:  2020-05-12       Impact factor: 6.313

Review 4.  The Risk of Sleep Disorder Among Persons with Mild Traumatic Brain Injury.

Authors:  Tatyana Mollayeva; Shirin Mollayeva; Angela Colantonio
Journal:  Curr Neurol Neurosci Rep       Date:  2016-06       Impact factor: 5.081

5.  Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits.

Authors:  Jacqueline M Lane; Jingjing Liang; Irma Vlasac; Simon G Anderson; David A Bechtold; Jack Bowden; Richard Emsley; Shubhroz Gill; Max A Little; Annemarie I Luik; Andrew Loudon; Frank A J L Scheer; Shaun M Purcell; Simon D Kyle; Deborah A Lawlor; Xiaofeng Zhu; Susan Redline; David W Ray; Martin K Rutter; Richa Saxena
Journal:  Nat Genet       Date:  2016-12-19       Impact factor: 38.330

6.  The Association of Dry Eye Symptom Severity and Comorbid Insomnia in US Veterans.

Authors:  Anat Galor; Benjamin E Seiden; Jasmine J Park; William J Feuer; Allison L McClellan; Elizabeth R Felix; Roy C Levitt; Constantine D Sarantopoulos; Douglas M Wallace
Journal:  Eye Contact Lens       Date:  2018-09       Impact factor: 3.152

7.  Genome-wide analysis of insomnia disorder.

Authors:  Murray B Stein; Michael J McCarthy; Chia-Yen Chen; Sonia Jain; Joel Gelernter; Feng He; Steven G Heeringa; Ronald C Kessler; Matthew K Nock; Stephan Ripke; Xiaoying Sun; Gary H Wynn; Jordan W Smoller; Robert J Ursano
Journal:  Mol Psychiatry       Date:  2018-03-08       Impact factor: 15.992

8.  Dopamine Receptor D2 Gene (DRD2) Polymorphisms, Job Stress, and Their Interaction on Sleep Dysfunction.

Authors:  Yu Jiang; Baoying Liu; Chuancheng Wu; Xiaoyan Gao; Yaoqin Lu; Yulong Lian; Jiwen Liu
Journal:  Int J Environ Res Public Health       Date:  2020-11-05       Impact factor: 3.390

Review 9.  Integrating the precision, sleep, and aerospace medicine fields: a systematic review of the genetic predisposition for obstructive sleep apnea in military aviation.

Authors:  Richard R Chapleau; Dara D Regn
Journal:  Sleep Breath       Date:  2021-07-07       Impact factor: 2.816

10.  A point mutation in the ion conduction pore of AMPA receptor GRIA3 causes dramatically perturbed sleep patterns as well as intellectual disability.

Authors:  Benjamin Davies; Laurence A Brown; Ondrej Cais; Jake Watson; Amber J Clayton; Veronica T Chang; Daniel Biggs; Christopher Preece; Polinka Hernandez-Pliego; Jon Krohn; Amarjit Bhomra; Stephen R F Twigg; Andrew Rimmer; Alexander Kanapin; Arjune Sen; Zenobia Zaiwalla; Gil McVean; Russell Foster; Peter Donnelly; Jenny C Taylor; Edward Blair; David Nutt; A Radu Aricescu; Ingo H Greger; Stuart N Peirson; Jonathan Flint; Hilary C Martin
Journal:  Hum Mol Genet       Date:  2017-10-15       Impact factor: 6.150
  10 in total

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