| Literature DB >> 26599498 |
Douglas Vernimmen1, Wendy A Bickmore2.
Abstract
Regulatory elements (enhancers) that are remote from promoters play a critical role in the spatial, temporal, and physiological control of gene expression. Studies on specific loci, together with genome-wide approaches, suggest that there may be many common mechanisms involved in enhancer-promoter communication. Here, we discuss the multiprotein complexes that are recruited to enhancers and the hierarchy of events taking place between regulatory elements and promoters.Mesh：
Year: 2015 PMID： 26599498 DOI： 10.1016/j.tig.2015.10.004
Source DB: PubMed Journal: Trends Genet ISSN： 0168-9525 Impact factor: 11.639