Literature DB >> 26595819

Total Synthesis of Linckosides A and B, the Representative Starfish Polyhydroxysteroid Glycosides with Neuritogenic Activities.

Dapeng Zhu1, Biao Yu1.   

Abstract

Linckosides A and B, two starfish metabolites with promising neuritogenic activities, are synthesized in a longest linear sequence of 32 steps and 0.5% overall yield; this represents the first synthesis of members of the polyhydroxysteroid glycoside family, which occur widely in starfishes.

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Year:  2015        PMID： 26595819     DOI： 10.1021/jacs.5b11276

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  7 in total

1.  Modular Total Synthesis and Cell-Based Anticancer Activity Evaluation of Ouabagenin and Other Cardiotonic Steroids with Varying Degrees of Oxygenation.

Authors:  Hem Raj Khatri; Bijay Bhattarai; Will Kaplan; Zhongzheng Li; Marcus John Curtis Long; Yimon Aye; Pavel Nagorny
Journal:  J Am Chem Soc       Date:  2019-03-14       Impact factor: 15.419

2.  Recent Progress in Steroid Synthesis Triggered by the Emergence of New Catalytic Methods.

Authors:  Hem Raj Khatri; Nolan Carney; Ryan Rutkoski; Bijay Bhattarai; Pavel Nagorny
Journal:  European J Org Chem       Date:  2020-01-01

3.  Total Syntheses of the Reported Structures of Curcusones I and J through Tandem Gold Catalysis.

Authors:  Yong Li; Mingji Dai
Journal:  Angew Chem Int Ed Engl       Date:  2017-08-10       Impact factor: 15.336

4.  Mn-, Fe-, and Co-Catalyzed Radical Hydrofunctionalizations of Olefins.

Authors:  Steven W M Crossley; Carla Obradors; Ruben M Martinez; Ryan A Shenvi
Journal:  Chem Rev       Date:  2016-07-27       Impact factor: 60.622

5.  Cytotoxic Polyhydroxysteroidal Glycosides from Starfish Culcita novaeguineae.

Authors:  Yunyang Lu; Hu Li; Minchang Wang; Yang Liu; Yingda Feng; Ke Liu; Haifeng Tang
Journal:  Mar Drugs       Date:  2018-03-13       Impact factor: 5.118

6.  Synthesis of the 8,19-Epoxysteroid Eurysterol A.

Authors:  Ömer Taspinar; Tobias Wilczek; Julian Erver; Martin Breugst; Jörg-Martin Neudörfl; Hans-Günther Schmalz
Journal:  Chemistry       Date:  2020-03-09       Impact factor: 5.236

7.  Fe-Catalyzed Anaerobic Mukaiyama-Type Hydration of Alkenes using Nitroarenes.

Authors:  Anup Bhunia; Klaus Bergander; Constantin Gabriel Daniliuc; Armido Studer
Journal:  Angew Chem Int Ed Engl       Date:  2021-03-03       Impact factor: 15.336
  7 in total

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