Literature DB >> 26593688

The resurgence of phenotypic screening in drug discovery and development.

Bridget K Wagner1.   

Abstract

Mesh：

Year:  2015        PMID： 26593688     DOI： 10.1517/17460441.2016.1122589

Source DB:  PubMed          Journal:  Expert Opin Drug Discov        ISSN： 1746-0441            Impact factor:   6.098


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  14 in total

1.  Computer-aided drug discovery research at a global contract research organization.

Authors:  Douglas B Kitchen
Journal:  J Comput Aided Mol Des       Date:  2016-11-01       Impact factor: 3.686

2.  The Resurrection of Phenotypic Drug Discovery.

Authors:  Wayne E Childers; Khaled M Elokely; Magid Abou-Gharbia
Journal:  ACS Med Chem Lett       Date:  2020-03-06       Impact factor: 4.345

Review 3.  Thermal proteome profiling: unbiased assessment of protein state through heat-induced stability changes.

Authors:  André Mateus; Tomi A Määttä; Mikhail M Savitski
Journal:  Proteome Sci       Date:  2017-06-24       Impact factor: 2.480

4.  Predicting the Reliability of Drug-target Interaction Predictions with Maximum Coverage of Target Space.

Authors:  Antonio Peón; Stefan Naulaerts; Pedro J Ballester
Journal:  Sci Rep       Date:  2017-06-19       Impact factor: 4.379

5.  Probing the chemical-biological relationship space with the Drug Target Explorer.

Authors:  Robert J Allaway; Salvatore La Rosa; Justin Guinney; Sara J C Gosline
Journal:  J Cheminform       Date:  2018-08-20       Impact factor: 5.514

Review 6.  Orthogonal Drug Pooling Enhances Phenotype-Based Discovery of Ocular Antiangiogenic Drugs in Zebrafish Larvae.

Authors:  Nils Ohnesorge; Temitope Sasore; Daniel Hillary; Yolanda Alvarez; Michelle Carey; Breandán N Kennedy
Journal:  Front Pharmacol       Date:  2019-05-24       Impact factor: 5.810

Review 7.  Emerging drug development technologies targeting ubiquitination for cancer therapeutics.

Authors:  Gianluca Veggiani; María Carla Rosales Gerpe; Sachdev S Sidhu; Wei Zhang
Journal:  Pharmacol Ther       Date:  2019-03-07       Impact factor: 12.310

Review 8.  Brief Overview of Approaches and Challenges in New Antibiotic Development: A Focus On Drug Repurposing.

Authors:  Natalie K Boyd; Chengwen Teng; Christopher R Frei
Journal:  Front Cell Infect Microbiol       Date:  2021-05-17       Impact factor: 5.293

Review 9.  Target-Directed Approaches for Screening Small Molecules against RNA Targets.

Authors:  Hafeez S Haniff; Laurent Knerr; Jonathan L Chen; Matthew D Disney; Helen L Lightfoot
Journal:  SLAS Discov       Date:  2020-05-18       Impact factor: 3.341

Review 10.  How Surrogate and Chemical Genetics in Model Organisms Can Suggest Therapies for Human Genetic Diseases.

Authors:  Katherine A Strynatka; Michelle C Gurrola-Gal; Jason N Berman; Christopher R McMaster
Journal:  Genetics       Date:  2018-03       Impact factor: 4.562
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