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Literature DB >> 26593638

Acyclic Cucurbit[n]uril Dendrimers.

David Sigwalt¹, Sarah Ahlbrand², Mingming Zhang¹, Brittany Vinciguerra¹, Volker Briken², Lyle Isaacs¹.

Abstract

The synthesis of acyclic cucurbit[n]uril dendrimers G1-G3 that bear four dendrons on their aromatic sidewalls via thiolate S(N)2 chemistry is reported. G1-G3 are polycationic and can bind to pEGFP plasmid DNA as shown by dynamic light scattering (DLS), gel electrophoresis, and scanning electron microscopy (SEM). The gene delivery ability of G1-G3 is presented.

Entities: Chemical

Mesh：

Substances：

Year: 2015 PMID： 26593638 PMCID： PMC4670575 DOI： 10.1021/acs.orglett.5b03145

Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005

45 in total

1. Controlling factors in the synthesis of cucurbituril and its homologues.

Authors: A Day; A P Arnold; R J Blanch; B Snushall
Journal: J Org Chem Date: 2001-11-30 Impact factor: 4.354

2. A cucurbituril-based gyroscane: a new supramolecular form.

Authors: Anthony I Day; Rodney J Blanch; Alan P Arnold; Susan Lorenzo; Gareth R Lewis; Ian Dance
Journal: Angew Chem Int Ed Engl Date: 2002-01-18 Impact factor: 15.336

3. Release of high-energy water as an essential driving force for the high-affinity binding of cucurbit[n]urils.

Authors: Frank Biedermann; Vanya D Uzunova; Oren A Scherman; Werner M Nau; Alfonso De Simone
Journal: J Am Chem Soc Date: 2012-09-10 Impact factor: 15.419

4. Cucurbit[10]uril.

Authors: Simin Liu; Peter Y Zavalij; Lyle Isaacs
Journal: J Am Chem Soc Date: 2005-12-07 Impact factor: 15.419

5. Daisy chain assembly formed from a cucurbit[6]uril derivative.

Authors: Liping Cao; Lyle Isaacs
Journal: Org Lett Date: 2012-05-31 Impact factor: 6.005

6. New dendrimers containing a single cobaltocenium unit covalently attached to the apical position of Newkome dendrons: electrochemistry and guest binding interactions with cucurbit[7]uril.

Authors: David Sobransingh; Angel E Kaifer
Journal: Langmuir Date: 2006-12-05 Impact factor: 3.882

7. Self-assembled ternary complex of cationic dendrimer, cucurbituril, and DNA: noncovalent strategy in developing a gene delivery carrier.

Authors: Yong-Beom Lim; Taeil Kim; Jae Wook Lee; Seon-Mi Kim; Hee-Joon Kim; Kimoon Kim; Jong-Sang Park
Journal: Bioconjug Chem Date: 2002 Nov-Dec Impact factor: 4.774

Acyclic Cucurbit[n]uril Dendrimers.

1. Controlling factors in the synthesis of cucurbituril and its homologues.

2. A cucurbituril-based gyroscane: a new supramolecular form.

3. Release of high-energy water as an essential driving force for the high-affinity binding of cucurbit[n]urils.

4. Cucurbit[10]uril.

5. Daisy chain assembly formed from a cucurbit[6]uril derivative.

6. New dendrimers containing a single cobaltocenium unit covalently attached to the apical position of Newkome dendrons: electrochemistry and guest binding interactions with cucurbit[7]uril.

7. Self-assembled ternary complex of cationic dendrimer, cucurbituril, and DNA: noncovalent strategy in developing a gene delivery carrier.

8. Photocontrol over cucurbit[8]uril complexes: stoichiometry and supramolecular polymers.

9. Molecular encapsulation by cucurbit[7]uril of the apical 4,4'-bipyridinium residue in newkome-type dendrimers.

10. Cucurbit[7]uril containers for targeted delivery of oxaliplatin to cancer cells.

1. Cationic acyclic cucurbit[n]uril-type containers: synthesis and molecular recognition toward nucleotides.