Literature DB >> 26588773

Not-So-Negative Selection.

Mark M Davis1.   

Abstract

It once seemed clear that negative selection of self-specific T cells in the thymus was the major mechanism of central tolerance. But recent studies, including Legoux et al. (2015) in this issue of Immunity, show that this is not always the case.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2015        PMID: 26588773     DOI: 10.1016/j.immuni.2015.11.002

Source DB:  PubMed          Journal:  Immunity        ISSN: 1074-7613            Impact factor:   31.745


  12 in total

1.  Islet-reactive CD8+ T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors.

Authors:  Slobodan Culina; Ana Ines Lalanne; Georgia Afonso; Karen Cerosaletti; Sheena Pinto; Guido Sebastiani; Klaudia Kuranda; Laura Nigi; Anne Eugster; Thomas Østerbye; Alicia Maugein; James E McLaren; Kristin Ladell; Etienne Larger; Jean-Paul Beressi; Anna Lissina; Victor Appay; Howard W Davidson; Søren Buus; David A Price; Matthias Kuhn; Ezio Bonifacio; Manuela Battaglia; Sophie Caillat-Zucman; Francesco Dotta; Raphael Scharfmann; Bruno Kyewski; Roberto Mallone
Journal:  Sci Immunol       Date:  2018-02-02

2.  Glimpse of natural selection of long-lived T-cell clones in healthy life.

Authors:  Baojun Zhang; Qingzhu Jia; Cheryl Bock; Gang Chen; Haili Yu; Qingshan Ni; Ying Wan; Qijing Li; Yuan Zhuang
Journal:  Proc Natl Acad Sci U S A       Date:  2016-08-17       Impact factor: 11.205

3.  In Praise of Descriptive Science: A Breath of Fresh AIRE.

Authors:  Mark M Davis
Journal:  Cell       Date:  2016-07-28       Impact factor: 41.582

Review 4.  Identifying and Targeting Human Tumor Antigens for T Cell-Based Immunotherapy of Solid Tumors.

Authors:  Vid Leko; Steven A Rosenberg
Journal:  Cancer Cell       Date:  2020-08-20       Impact factor: 31.743

Review 5.  Relationship between CD4 Regulatory T Cells and Anergy In Vivo.

Authors:  Lokesh A Kalekar; Daniel L Mueller
Journal:  J Immunol       Date:  2017-04-01       Impact factor: 5.422

6.  Rapid Assessment of T-Cell Receptor Specificity of the Immune Repertoire.

Authors:  Xingcheng Lin; Jason T George; Nicholas P Schafer; Kevin Ng Chau; Michael E Birnbaum; Cecilia Clementi; José N Onuchic; Herbert Levine
Journal:  Nat Comput Sci       Date:  2021-05-24

7.  Sustained Coevolution in a Stochastic Model of Cancer-Immune Interaction.

Authors:  Jason T George; Herbert Levine
Journal:  Cancer Res       Date:  2019-12-20       Impact factor: 12.701

Review 8.  Breast cancer dormancy: need for clinically relevant models to address current gaps in knowledge.

Authors:  Grace G Bushnell; Abhijeet P Deshmukh; Petra den Hollander; Ming Luo; Rama Soundararajan; Dongya Jia; Herbert Levine; Sendurai A Mani; Max S Wicha
Journal:  NPJ Breast Cancer       Date:  2021-05-28

9.  CD8+ T Cells Variably Recognize Native Versus Citrullinated GRP78 Epitopes in Type 1 Diabetes.

Authors:  Marie Eliane Azoury; Fatoumata Samassa; Mijke Buitinga; Laura Nigi; Noemi Brusco; Aïsha Callebaut; Matthieu Giraud; Magali Irla; Ana Ines Lalanne; Alexia Carré; Georgia Afonso; Zhicheng Zhou; Barbara Brandao; Maikel L Colli; Guido Sebastiani; Francesco Dotta; Maki Nakayama; Decio L Eizirik; Sylvaine You; Sheena Pinto; Mark J Mamula; Yann Verdier; Joelle Vinh; Soren Buus; Chantal Mathieu; Lut Overbergh; Roberto Mallone
Journal:  Diabetes       Date:  2021-09-24       Impact factor: 9.461

10.  The Thymus/Neocortex Hypothesis of the Brain: A Cell Basis for Recognition and Instruction of Self.

Authors:  Silvia Sánchez-Ramón; Florence Faure
Journal:  Front Cell Neurosci       Date:  2017-10-27       Impact factor: 5.505

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