| Literature DB >> 26588773 |
Abstract
It once seemed clear that negative selection of self-specific T cells in the thymus was the major mechanism of central tolerance. But recent studies, including Legoux et al. (2015) in this issue of Immunity, show that this is not always the case.Mesh:
Substances:
Year: 2015 PMID: 26588773 DOI: 10.1016/j.immuni.2015.11.002
Source DB: PubMed Journal: Immunity ISSN: 1074-7613 Impact factor: 31.745