Literature DB >> 27471960

In Praise of Descriptive Science: A Breath of Fresh AIRE.

Mark M Davis1.   

Abstract

Meyer et al. find that subjects lacking the AIRE gene, critical for self-tolerance in T lymphocytes, show a broad range of autoantibody specificities, which can have extremely high affinities. The data also suggest that some of these autoantibodies can, surprisingly, prevent some types of autoimmunity, particularly type I diabetes.
Copyright © 2016. Published by Elsevier Inc.

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Year:  2016        PMID： 27471960      PMCID： PMC5294994          DOI： 10.1016/j.cell.2016.07.018

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  9 in total

1.  Not-So-Negative Selection.

Authors:  Mark M Davis
Journal:  Immunity       Date:  2015-11-17       Impact factor: 31.745

2.  Extrathymic Aire-expressing cells are a distinct bone marrow-derived population that induce functional inactivation of CD4⁺ T cells.

Authors:  James M Gardner; Todd C Metzger; Eileen J McMahon; Byron B Au-Yeung; Anna K Krawisz; Wen Lu; Jeffrey D Price; Kellsey P Johannes; Ansuman T Satpathy; Kenneth M Murphy; Kristin V Tarbell; Arthur Weiss; Mark S Anderson
Journal:  Immunity       Date:  2013-08-29       Impact factor: 31.745

3.  The cellular mechanism of Aire control of T cell tolerance.

Authors:  Mark S Anderson; Emily S Venanzi; Zhibin Chen; Stuart P Berzins; Christophe Benoist; Diane Mathis
Journal:  Immunity       Date:  2005-08       Impact factor: 31.745

Review 4.  Aire.

Authors:  Diane Mathis; Christophe Benoist
Journal:  Annu Rev Immunol       Date:  2009       Impact factor: 28.527

5.  An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains.

Authors: 
Journal:  Nat Genet       Date:  1997-12       Impact factor: 38.330

6.  Positional cloning of the APECED gene.

Authors:  K Nagamine; P Peterson; H S Scott; J Kudoh; S Minoshima; M Heino; K J Krohn; M D Lalioti; P E Mullis; S E Antonarakis; K Kawasaki; S Asakawa; F Ito; N Shimizu
Journal:  Nat Genet       Date:  1997-12       Impact factor: 38.330

7.  Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines.

Authors:  Kai Kisand; Anette S Bøe Wolff; Katarina Trebusak Podkrajsek; Liina Tserel; Maire Link; Kalle V Kisand; Elisabeth Ersvaer; Jaakko Perheentupa; Martina Moter Erichsen; Nina Bratanic; Antonella Meloni; Filomena Cetani; Roberto Perniola; Berrin Ergun-Longmire; Noel Maclaren; Kai J E Krohn; Mikulás Pura; Berthold Schalke; Philipp Ströbel; Maria Isabel Leite; Tadej Battelino; Eystein S Husebye; Pärt Peterson; Nick Willcox; Anthony Meager
Journal:  J Exp Med       Date:  2010-02-01       Impact factor: 14.307

8.  Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity.

Authors:  Zahra Sabouri; Peter Schofield; Keisuke Horikawa; Emily Spierings; David Kipling; Katrina L Randall; David Langley; Brendan Roome; Rodrigo Vazquez-Lombardi; Romain Rouet; Jana Hermes; Tyani D Chan; Robert Brink; Deborah K Dunn-Walters; Daniel Christ; Christopher C Goodnow
Journal:  Proc Natl Acad Sci U S A       Date:  2014-05-12       Impact factor: 11.205

9.  AIRE-Deficient Patients Harbor Unique High-Affinity Disease-Ameliorating Autoantibodies.

Authors:  Steffen Meyer; Martin Woodward; Christina Hertel; Philip Vlaicu; Yasmin Haque; Jaanika Kärner; Annalisa Macagno; Shimobi C Onuoha; Dmytro Fishman; Hedi Peterson; Kaja Metsküla; Raivo Uibo; Kirsi Jäntti; Kati Hokynar; Anette S B Wolff; Kai Krohn; Annamari Ranki; Pärt Peterson; Kai Kisand; Adrian Hayday
Journal:  Cell       Date:  2016-07-14       Impact factor: 41.582
  9 in total
  1 in total

1.  New Perspectives in Rheumatology: May You Live in Interesting Times: Challenges and Opportunities in Lupus Research.

Authors:  Iñaki Sanz
Journal:  Arthritis Rheumatol       Date:  2017-06-16       Impact factor: 10.995
  1 in total

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