Literature DB >> 26584226

Diagnostic value of CT-localizer and axial low-dose computed tomography for the detection of drug body packing.

Joel Aissa1, Antonia Kohlmeier2, Christian Rubbert2, Ulrich Hohn3, Dirk Blondin4, Christoph Schleich2, Patric Kröpil2, Johannes Boos2, Gerald Antoch2, Falk Miese2.   

Abstract

OBJECTIVES: The purpose of this study was to assess the diagnostic performance of CT-localizers in the detection of intracorporal containers.
METHODS: This study was approved by the research ethics committee of our clinic. From March 2012 to March 2013, 108 subjects were referred to our institute with suspected body packing. The CT-localizer and the axial CT-images were compared by two blinded observers retrospectively. Presence of body packs was assessed in consensus. Sensitivity and specificity, PPV and NPV of the CT-localizer were calculated.
RESULTS: Packets were detected in the CT-localizer of 19 suspects. In 28 of 108 cases packs were detected in axial CT-images. Sensitivity of CT-localizer for detection of packs was 0.68, and specificity was 1.00. There were no cases rated as false positive. The PPV was 1.0 and the NPV was 0.89. The omission of the axial CT-images would have led to a mean radiation dose reduction of 1.94 ± 0.5 mSv.
CONCLUSIONS: The value of CT-localizers lies in their high PPV. Localizers are limited by low sensitivity, compared to axial CT-images in screening of potential body packers. However, in positive cases their high PPV may possibly allow to omit the complete axial abdominal CT to achieve even lower radiation exposure.
Copyright © 2015 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

Keywords:  Body packing; CT; Cocaine; Dose reduction; Localizer

Mesh:

Year:  2015        PMID: 26584226     DOI: 10.1016/j.jflm.2015.10.009

Source DB:  PubMed          Journal:  J Forensic Leg Med        ISSN: 1752-928X            Impact factor:   1.614


  1 in total

1.  Noise insertion in CT for cocaine body packing: where is the limit of extensive dose reduction?

Authors:  Joel Aissa; Edwin Bölke; Lino M Sawicki; Elisabeth Appel; Christoph Thomas; Philipp Heusch; Martin Sedlmair; Karl Krzymyk; Patric Kröpil; Gerald Antoch; Johannes Boos
Journal:  Eur J Med Res       Date:  2018-12-07       Impact factor: 2.175

  1 in total

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