| Literature DB >> 26568057 |
Crochan John O'Sullivan1, Eva Bühlmann Lerjen1, Daniela Pellegrini2, Franz Robert Eberli1.
Abstract
The choice of prosthetic valve to implant in women of childbearing age requiring a valve replacement is challenging. Mechanical valves mandate the use of oral anticoagulation (OAC) for the prevention of thromboembolic complications, but the use of OAC during pregnancy can lead to maternal and fetal complications, in particular, warfarin embryopathy. Conversely, the use of bioprosthetic valves during pregnancy eliminates the need for OAC, but can instead be associated with accelerated structural valve degeneration. We present the case of a 31-year-old woman with a bioprosthetic valve in the aortic position, who developed undetected accelerated structural valve degeneration 5.5 years following implantation of a Mitroflow bioprosthetic aortic valve, and who suffered a catastrophic complication during emergency caesarean delivery as a result. 2015 BMJ Publishing Group Ltd.Entities:
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Year: 2015 PMID: 26568057 PMCID: PMC4671250 DOI: 10.1136/bcr-2015-212575
Source DB: PubMed Journal: BMJ Case Rep ISSN: 1757-790X