Literature DB >> 26567788

Number of People Blind or Visually Impaired by Cataract Worldwide and in World Regions, 1990 to 2010.

Moncef Khairallah1, Rim Kahloun1, Rupert Bourne2, Hans Limburg3, Seth R Flaxman4, Jost B Jonas5, Jill Keeffe6, Janet Leasher7, Kovin Naidoo8, Konrad Pesudovs9, Holly Price2, Richard A White10, Tien Y Wong11, Serge Resnikoff12, Hugh R Taylor13.   

Abstract

PURPOSE: To estimate prevalence and number of people visually impaired or blind due to cataract.
METHODS: Based on the Global Burden of Diseases Study 2010 and ongoing literature research, we examined how many people were affected by moderate to severe vision impairment (MSVI; presenting visual acuity <6/18, ≥3/60) and blindness (presenting visual acuity <3/60) due to cataract.
RESULTS: In 2010, of overall 32.4 million blind and 191 million vision impaired, 10.8 million people were blind and 35.1 million were visually impaired due to cataract. Cataract caused worldwide 33.4% of all blindness in 2010, and 18.4% of all MSVI. These figures were lower in the high-income regions (<15%) and higher (>40%) in South and Southeast Asia and Oceania. From 1990 to 2010, the number of blind or visually impaired due to cataract decreased by 11.4% and by 20.2%, respectively; the age-standardized global prevalence of cataract-related blindness and MSVI reduced by 46% and 50%, respectively, and the worldwide crude prevalence of cataract-related blindness and MSVI reduced by 32% and 39%, respectively. The percentage of global blindness and MSVI caused by cataract decreased from 38.6% to 33.4%, and from 25.6% to 18.4%, respectively. This decrease took place in almost all world regions, except East Sub-Saharan Africa.
CONCLUSIONS: In 2010, one in three blind people was blind due to cataract, and one of six visually impaired people was visually impaired due to cataract. Despite major improvements in terms of reduction of prevalence, cataract remains a major public health problem.

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Year:  2015        PMID: 26567788     DOI: 10.1167/iovs.15-17201

Source DB:  PubMed          Journal:  Invest Ophthalmol Vis Sci        ISSN: 0146-0404            Impact factor:   4.799


  99 in total

Review 1.  Association between the 8-oxoguanine DNA glycosylase gene Ser326Cys polymorphism and age-related cataract: a systematic review and meta-analysis.

Authors:  Xiao-Cui Liu; Xiao-Hui Guo; Bing Chen; Zhao-Hui Li; Xiao-Fei Liu
Journal:  Int Ophthalmol       Date:  2017-06-19       Impact factor: 2.031

Review 2.  Phototoxicity of environmental radiations in human lens: revisiting the pathogenesis of UV-induced cataract.

Authors:  Farzin Kamari; Shahin Hallaj; Fatemeh Dorosti; Farbod Alinezhad; Negar Taleschian-Tabrizi; Fereshteh Farhadi; Hassan Aslani
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2019-06-21       Impact factor: 3.117

3.  Relationship between diabetes mellitus and cataract in Hungary.

Authors:  Anita Pék; Dorottya Szabó; Gábor László Sándor; Gábor Tóth; András Papp; Zoltán Zsolt Nagy; Hans Limburg; János Németh
Journal:  Int J Ophthalmol       Date:  2020-05-18       Impact factor: 1.779

Review 4.  Vitamin C and the Lens: New Insights into Delaying the Onset of Cataract.

Authors:  Julie C Lim; Mariana Caballero Arredondo; Andrea J Braakhuis; Paul J Donaldson
Journal:  Nutrients       Date:  2020-10-14       Impact factor: 5.717

5.  Expression and regulation of microRNA-29a and microRNA-29c in early diabetic rat cataract formation.

Authors:  Ying Sun; Chun-Mei Lu; Zhen Song; Ke-Ke Xu; Shu-Bin Wu; Zhi-Jian Li
Journal:  Int J Ophthalmol       Date:  2016-12-18       Impact factor: 1.779

6.  Aldose reductase inhibition enhances lens regeneration in mice.

Authors:  Leonid M Zukin; Michelle G Pedler; Kevin Chyung; Sarah Seiwald; Patricia Lenhart; Biehuoy Shieh; J Mark Petrash
Journal:  Chem Biol Interact       Date:  2019-04-23       Impact factor: 5.192

Review 7.  Personalized aspheric intraocular lens implantation based on corneal spherical aberration: a review.

Authors:  Wei Du; Wei Lou; Qiang Wu
Journal:  Int J Ophthalmol       Date:  2019-11-18       Impact factor: 1.779

8.  ERK1/2 signaling is required for the initiation but not progression of TGFβ-induced lens epithelial to mesenchymal transition (EMT).

Authors:  Magdalena C Wojciechowski; Leila Mahmutovic; Daisy Y Shu; Frank J Lovicu
Journal:  Exp Eye Res       Date:  2017-03-30       Impact factor: 3.467

9.  Cataract surgeon viewpoints on the need for novel preventative anti-inflammatory and anti-posterior capsular opacification therapies.

Authors:  Mahbubul H Shihan; Samuel G Novo; Melinda K Duncan
Journal:  Curr Med Res Opin       Date:  2019-08-28       Impact factor: 2.580

10.  Fibronectin has multifunctional roles in posterior capsular opacification (PCO).

Authors:  Mahbubul H Shihan; Mallika Kanwar; Yan Wang; Erin E Jackson; Adam P Faranda; Melinda K Duncan
Journal:  Matrix Biol       Date:  2020-03-12       Impact factor: 11.583

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