Raman spectroscopy for cancer diagnosis: how far have we come?

Raman spectroscopy is increasingly investigated for cancer diagnosis. As the potential of the technique is explored and realized, it is slowly making its way into clinics. There are more reports in recent years showing promise that it can help clinicians for cancer diagnosis. However, a number of challenges remain to be overcome, especially in vivo cancer diagnosis. In this article, the recent progress of the technique toward clinical cancer diagnosis is discussed from a critical perspective.