Febe Renjitha Suman1, Reddy S Sudheer Raj2, N Priyathersini3, Rithika Rajendran4, Rashmika Rajendran5, Umalakshmi Ramadoss6. 1. Professor, Department of Pathology, Sri Ramachandra Medical College and Research Institute , Porur, Chennai, India . 2. Student, Department of Pathology, Sri Ramachandra Medical College and Research Institute , Porur, Chennai, India . 3. Assistant Professor, Department of Pathology, Sri Ramachandra Medical College and Research Institute , Porur, Chennai, India . 4. Post Graduate Student, Department of Pathology, Sri Ramachandra Medical College and Research Institute , Porur, Chennai, India . 5. CRRI, Department of Pathology, Sri Ramachandra Medical College and Research Institute , Porur, Chennai, India . 6. Clinical Instructor, Department of Pathology, Sri Ramachandra Medical College and Research Institute , Porur, Chennai, India .
Abstract
INTRODUCTION: Umbilical cord blood (UCB) a source of hematopoietic stem cells, is also an acceptable sample to assess neonatal sepsis. Though reports are available for stem cell counts very minimal literature is available regarding hematologic parameters, which may vary on ethnicity. AIM: To establish biological reference interval for hematological parameters of umbilical cord blood to guide neonatologists, hematopoietic stem cell transplant specialists and future analysis. MATERIALS AND METHODS: Prospective longitudinal study was done from January 2014 to April 2014 after ethics committee approval. UCB from 120 full term new borns of normal birth weight born out of uneventful pregnancy to mothers aged between 21 to 45 years with hemoglobin above 10g/dL were processed in Beckman Coulter LH780 analyzer for complete blood count and counter checked by peripheral smear. Results tabulated in Microsoft excel are analyzed using IBM SPSS statistics 16 software. RESULTS: Male to female ratio is 1:1.05. There is no difference in the values between males and females. When compared with few studies available, though many values are comparable a few values are not comparable. CONCLUSION: This study can be a useful guide to neonatologists, hematopoietic stem cells transplant hematologists and future analysis.
INTRODUCTION: Umbilical cord blood (UCB) a source of hematopoietic stem cells, is also an acceptable sample to assess neonatal sepsis. Though reports are available for stem cell counts very minimal literature is available regarding hematologic parameters, which may vary on ethnicity. AIM: To establish biological reference interval for hematological parameters of umbilical cord blood to guide neonatologists, hematopoietic stem cell transplant specialists and future analysis. MATERIALS AND METHODS: Prospective longitudinal study was done from January 2014 to April 2014 after ethics committee approval. UCB from 120 full term new borns of normal birth weight born out of uneventful pregnancy to mothers aged between 21 to 45 years with hemoglobin above 10g/dL were processed in Beckman Coulter LH780 analyzer for complete blood count and counter checked by peripheral smear. Results tabulated in Microsoft excel are analyzed using IBM SPSS statistics 16 software. RESULTS: Male to female ratio is 1:1.05. There is no difference in the values between males and females. When compared with few studies available, though many values are comparable a few values are not comparable. CONCLUSION: This study can be a useful guide to neonatologists, hematopoietic stem cells transplant hematologists and future analysis.
Authors: Kristina Gervin; Christian Magnus Page; Hans Christian D Aass; Michelle A Jansen; Heidi Elisabeth Fjeldstad; Bettina Kulle Andreassen; Liesbeth Duijts; Joyce B van Meurs; Menno C van Zelm; Vincent W Jaddoe; Hedvig Nordeng; Gunn Peggy Knudsen; Per Magnus; Wenche Nystad; Anne Cathrine Staff; Janine F Felix; Robert Lyle Journal: Epigenetics Date: 2016-09 Impact factor: 4.528
Authors: Andres Cardenas; Catherine Allard; Myriam Doyon; E Andres Houseman; Kelly M Bakulski; Patrice Perron; Luigi Bouchard; Marie-France Hivert Journal: Epigenetics Date: 2016-09-26 Impact factor: 4.528