Literature DB >> 2655549

Effects of nucleotides and divalent cations on phospholipase activity in Saccharomyces cerevisiae.

W Witt1, P Hampel, K Böcker, A Mertsching.   

Abstract

Divalent cations activate the lysophospholipase and transacylase reactions catalyzed by the same enzymes in the yeast Saccharomyces cerevisiae. The activation was observed at neutral pH, but not at the pH optimum of lysophospholipase/transacylase, near 3.5. Adenine nucleotides, especially AMP and ADP, are strong inhibitors of the same group of enzymes. Half maximal inhibition by AMP was found at a concentration of about 20 microM. The inhibition by nucleotides in low concentrations is enhanced by divalent cations.

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Year:  1989        PMID: 2655549     DOI: 10.1007/bf00414431

Source DB:  PubMed          Journal:  Arch Microbiol        ISSN: 0302-8933            Impact factor:   2.552


  21 in total

Review 1.  Phospholipid metabolism.

Authors:  W C McMurray; W L Magee
Journal:  Annu Rev Biochem       Date:  1972       Impact factor: 23.643

2.  The isolation of Saccharomyces cerevisiae nuclear membranes with nuclease and high-salt treatment.

Authors:  K Mann; D Mecke
Journal:  Biochim Biophys Acta       Date:  1982-04-23

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Authors:  G F Fuhrmann; C Boehm; A P Theuvenet
Journal:  Biochim Biophys Acta       Date:  1976-05-21

4.  Purification and properties of a phospholipid acyl hydrolase from plasma membranes of Saccharomyces cerevisiae.

Authors:  W Witt; H J Brüller; G Falker; G F Fuhrmann
Journal:  Biochim Biophys Acta       Date:  1982-06-11

5.  Secretion of phospholipase B from Saccharomyces cerevisiae.

Authors:  W Witt; A Mertsching; E König
Journal:  Biochim Biophys Acta       Date:  1984-08-15

6.  Inhibition of yeast phosphatidic-acid synthesis by free fatty acids.

Authors:  M Morikawa; S Yamashita
Journal:  Eur J Biochem       Date:  1978-03

7.  AMP deaminase as a control system of glycolysis in yeast. Mechanism of the inhibition of glycolysis by fatty acid and citrate.

Authors:  M Yoshino; K Murakami
Journal:  J Biol Chem       Date:  1982-09-25       Impact factor: 5.157

8.  Changes in the intracellular concentrations of adenosine phosphates and nicotinamide nucleotides during the aerobic growth cycle of yeast on different carbon sources.

Authors:  E S Polakis; W Bartley
Journal:  Biochem J       Date:  1966-06       Impact factor: 3.857

9.  Inhibition of the reductive activation of a valyl-tRNA synthetase from yeast by unsaturated fatty acids and associated observations on newly found lipophilic substances from yeast.

Authors:  S Black
Journal:  J Biol Chem       Date:  1985-01-10       Impact factor: 5.157

10.  Purification of a phospholipase B inhibitor from Saccharomyces cerevisiae.

Authors:  W Witt; R Treude; D Werner
Journal:  Biochim Biophys Acta       Date:  1985-04-25
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  1 in total

1.  Regulation of activity in vitro and in vivo of three phospholipases B from Saccharomyces cerevisiae.

Authors:  Olaf Merkel; Olga V Oskolkova; Florian Raab; Rosemarie El-Toukhy; Fritz Paltauf
Journal:  Biochem J       Date:  2005-04-15       Impact factor: 3.857

  1 in total

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