Literature DB >> 2654538

Genetics of pertussis toxin.

R Gross1, B Aricò, R Rappuoli.   

Abstract

Pertussis toxin (PT) is the major virulence factor of Bordetella pertussis. The cloning and nucleotide sequencing of the PT genes from B. pertussis, Bordetella parapertussis and Bordetella bronchiseptica has elucidated the evolution of the Bordetella species and allowed considerable advances towards the understanding of their gene expression and the development of safer vaccines against pertussis.

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Year:  1989        PMID： 2654538     DOI： 10.1111/j.1365-2958.1989.tb00111.x

Source DB:  PubMed          Journal:  Mol Microbiol        ISSN： 0950-382X            Impact factor:   3.501


  11 in total

1.  Uptake and intracellular survival of Bordetella pertussis in human macrophages.

Authors:  R L Friedman; K Nordensson; L Wilson; E T Akporiaye; D E Yocum
Journal:  Infect Immun       Date:  1992-11       Impact factor: 3.441

2.  Positive transcriptional feedback at the bvg locus controls expression of virulence factors in Bordetella pertussis.

Authors:  V Scarlato; A Prugnola; B Aricó; R Rappuoli
Journal:  Proc Natl Acad Sci U S A       Date:  1990-09       Impact factor: 11.205

3.  Identification of linear B-cell determinants of pertussis toxin associated with the receptor recognition site of the S3 subunit.

Authors:  M A Schmidt; B Raupach; M Szulczynski; J Marzillier
Journal:  Infect Immun       Date:  1991-04       Impact factor: 3.441

4.  Characterization of the fim2 and fim3 fimbrial subunit genes of Bordetella bronchiseptica: roles of Fim2 and Fim3 fimbriae and flagella in adhesion.

Authors:  P H Savelkoul; D P de Kerf; R J Willems; F R Mooi; B A van der Zeijst; W Gaastra
Journal:  Infect Immun       Date:  1996-12       Impact factor: 3.441

5.  Polymorphism in the pertussis toxin promoter region affecting the DNA-based diagnosis of Bordetella infection.

Authors:  M Nygren; E Reizenstein; M Ronaghi; J Lundeberg
Journal:  J Clin Microbiol       Date:  2000-01       Impact factor: 5.948

6.  Adhesion of Bordetella pertussis to eukaryotic cells requires a time-dependent export and maturation of filamentous hemagglutinin.

Authors:  B Aricò; S Nuti; V Scarlato; R Rappuoli
Journal:  Proc Natl Acad Sci U S A       Date:  1993-10-01       Impact factor: 11.205

7.  Characterization of defensin resistance phenotypes associated with mutations in the phoP virulence regulon of Salmonella typhimurium.

Authors:  S I Miller; W S Pulkkinen; M E Selsted; J J Mekalanos
Journal:  Infect Immun       Date:  1990-11       Impact factor: 3.441

8.  bvg Repression of alcaligin synthesis in Bordetella bronchiseptica is associated with phylogenetic lineage.

Authors:  P C Giardina; L A Foster; J M Musser; B J Akerley; J F Miller; D W Dyer
Journal:  J Bacteriol       Date:  1995-11       Impact factor: 3.490

9.  Constitutive sensory transduction mutations in the Bordetella pertussis bvgS gene.

Authors:  J F Miller; S A Johnson; W J Black; D T Beattie; J J Mekalanos; S Falkow
Journal:  J Bacteriol       Date:  1992-02       Impact factor: 3.490

10.  Flagellin gene transcription in Bordetella bronchiseptica is regulated by the BvgAS virulence control system.

Authors:  B J Akerley; J F Miller
Journal:  J Bacteriol       Date:  1993-06       Impact factor: 3.490
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