Literature DB >> 26537447

Detecting 16S rRNA Methyltransferases in Enterobacteriaceae by Use of Arbekacin.

Patrick McGann1, Sarah Chahine2, Darius Okafor2, Ana C Ong2, Rosslyn Maybank2, Yoon I Kwak2, Kerry Wilson3, Michael Zapor4, Emil Lesho2, Mary Hinkle2.   

Abstract

16S rRNA methyltransferases confer resistance to most aminoglycosides, but discriminating their activity from that of aminoglycoside-modifying enzymes (AMEs) is challenging using phenotypic methods. We demonstrate that arbekacin, an aminoglycoside refractory to most AMEs, can rapidly detect 16S methyltransferase activity in Enterobacteriaceae with high specificity using the standard disk susceptibility test.
Copyright © 2015, American Society for Microbiology. All Rights Reserved.

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Year:  2015        PMID： 26537447      PMCID： PMC4702724          DOI： 10.1128/JCM.02642-15

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  22 in total

1.  Updated multiplex polymerase chain reaction for detection of 16S rRNA methylases: high prevalence among NDM-1 producers.

Authors:  Béatrice Berçot; Laurent Poirel; Patrice Nordmann
Journal:  Diagn Microbiol Infect Dis       Date:  2011-10-13       Impact factor: 2.803

2.  Surveillance, characterisation, and preservation of multidrug-resistant bacteria.

Authors:  Emil Lesho; David Craft; Benjamin C Kirkup; Paige Waterman; Amy Summers; Maryanne T Vahey; Kent E Kester; Robert Bowden
Journal:  Lancet Infect Dis       Date:  2011-01       Impact factor: 25.071

3.  Dissemination of multidrug-resistant Klebsiella pneumoniae clinical isolates with various combinations of carbapenemases (NDM-1 and OXA-72) and 16S rRNA methylases (ArmA, RmtC and RmtF) in Nepal.

Authors:  Tatsuya Tada; Tohru Miyoshi-Akiyama; Rajan K Dahal; Shyam K Mishra; Hiroshi Ohara; Kayo Shimada; Teruo Kirikae; Bharat M Pokhrel
Journal:  Int J Antimicrob Agents       Date:  2013-08-24       Impact factor: 5.283

4.  Novel 16S rRNA methyltransferase RmtH produced by Klebsiella pneumoniae associated with war-related trauma.

Authors:  Jessica A O'Hara; Patrick McGann; Erik C Snesrud; Robert J Clifford; Paige E Waterman; Emil P Lesho; Yohei Doi
Journal:  Antimicrob Agents Chemother       Date:  2013-03-11       Impact factor: 5.191

5.  Loop-mediated isothermal amplification assay for 16S rRNA methylase genes in Gram-negative bacteria.

Authors:  Mitsuaki Nagasawa; Mitsuo Kaku; Kazunari Kamachi; Keigo Shibayama; Yoshichika Arakawa; Keizo Yamaguchi; Yoshikazu Ishii
Journal:  J Infect Chemother       Date:  2014-08-30       Impact factor: 2.211

6.  Further proofs of concept for the Carba NP test.

Authors:  Laurent Dortet; Laurent Poirel; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2014       Impact factor: 5.191

7.  Semisynthetic aminoglycoside antibiotics: Development and enzymatic modifications.

Authors:  S. Kondo; Kunimoto Hotta
Journal:  J Infect Chemother       Date:  1999-03       Impact factor: 2.211

8.  Worldwide disseminated armA aminoglycoside resistance methylase gene is borne by composite transposon Tn1548.

Authors:  M Galimand; S Sabtcheva; P Courvalin; T Lambert
Journal:  Antimicrob Agents Chemother       Date:  2005-07       Impact factor: 5.191

9.  Association of the novel aminoglycoside resistance determinant RmtF with NDM carbapenemase in Enterobacteriaceae isolated in India and the UK.

Authors:  Laura Hidalgo; Katie L Hopkins; Belen Gutierrez; Cristina M Ovejero; Suruchi Shukla; Stephen Douthwaite; Kashi N Prasad; Neil Woodford; Bruno Gonzalez-Zorn
Journal:  J Antimicrob Chemother       Date:  2013-04-11       Impact factor: 5.790

10.  The novel enzymatic 3''-N-acetylation of arbekacin by an aminoglycoside 3-N-acetyltransferase of Streptomyces origin and the resulting activity.

Authors:  K Hotta; A Sunada; J Ishikawa; S Mizuno; Y Ikeda; S Kondo
Journal:  J Antibiot (Tokyo)       Date:  1998-08       Impact factor: 2.649
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  1 in total

1.  The First Saudi Study Investigating the Plasmid-borne Aminoglycoside and Sulfonamide Resistance among Acinetobacter baumannii Clinical Isolates Genotyped by RAPD-PCR: the Declaration of a Novel Allelic Variant Called aac(6')-SL and Three Novel Mutations in the sul1 Gene in the Acinetobacter Plasmid (s).

Authors:  Mohamed F El-Badawy; Fatma I Abou-Elazm; Mohamed S Omar; Mostafa E El-Naggar; Ibrahim A Maghrabi
Journal:  Infect Drug Resist       Date:  2021-11-12       Impact factor: 4.003
  1 in total

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