Literature DB >> 26528949

Understanding Parkinson Disease: A Complex and Multifaceted Illness.

Apoorva Gopalakrishna1, Sheila A Alexander.   

Abstract

Parkinson disease is an incredibly complex and multifaceted illness affecting millions of people in the United States. Parkinson disease is characterized by progressive dopaminergic neuronal dysfunction and loss, leading to debilitating motor, cognitive, and behavioral symptoms. Parkinson disease is an enigmatic illness that is still extensively researched today to search for a better understanding of the disease, develop therapeutic interventions to halt or slow progression of the disease, and optimize patient outcomes. This article aims to examine in detail the normal function of the basal ganglia and dopaminergic neurons in the central nervous system, the etiology and pathophysiology of Parkinson disease, related signs and symptoms, current treatment, and finally, the profound impact of understanding the disease on nursing care.

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Year:  2015        PMID: 26528949     DOI: 10.1097/JNN.0000000000000162

Source DB:  PubMed          Journal:  J Neurosci Nurs        ISSN: 0888-0395            Impact factor:   1.230


  10 in total

Review 1.  Fragile X-associated tremor/ataxia syndrome: phenotypic comparisons with other movement disorders.

Authors:  Erin E Robertson; Deborah A Hall; Andrew R McAsey; Joan A O'Keefe
Journal:  Clin Neuropsychol       Date:  2016-08       Impact factor: 3.535

2.  β-Caryophyllene, a phytocannabinoid attenuates oxidative stress, neuroinflammation, glial activation, and salvages dopaminergic neurons in a rat model of Parkinson disease.

Authors:  Shreesh Ojha; Hayate Javed; Sheikh Azimullah; M Emdadul Haque
Journal:  Mol Cell Biochem       Date:  2016-06-17       Impact factor: 3.396

3.  Cannabinoid Receptors and Ligands: Lessons from CNS Disorders and the Quest for Novel Treatment Venues.

Authors:  Clara M Vecchini Rodríguez; Yma Escalona Meléndez; Jacqueline Flores-Otero
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

4.  Speech and communication in Parkinson's disease: a cross-sectional exploratory study in the UK.

Authors:  Maxwell S Barnish; Simon M C Horton; Zoe R Butterfint; Allan B Clark; Rachel A Atkinson; Katherine H O Deane
Journal:  BMJ Open       Date:  2017-05-29       Impact factor: 2.692

5.  Mesenchymal stem cells that located in the electromagnetic fields improves rat model of Parkinson's disease.

Authors:  Majid Jadidi; Saeed Moghadas Biat; Hamid Reza Sameni; Manouchehr Safari; Abbas Ali Vafaei; Laya Ghahari
Journal:  Iran J Basic Med Sci       Date:  2016-07       Impact factor: 2.699

Review 6.  Microglia Response During Parkinson's Disease: Alpha-Synuclein Intervention.

Authors:  Sara A Ferreira; Marina Romero-Ramos
Journal:  Front Cell Neurosci       Date:  2018-08-06       Impact factor: 5.505

Review 7.  Phosphoinositides: Roles in the Development of Microglial-Mediated Neuroinflammation and Neurodegeneration.

Authors:  Thomas Ernest James Phillips; Emily Maguire
Journal:  Front Cell Neurosci       Date:  2021-03-26       Impact factor: 5.505

Review 8.  Phytochemicals as inhibitors of tumor necrosis factor alpha and neuroinflammatory responses in neurodegenerative diseases.

Authors:  Fatemeh Zahedipour; Seyede Atefe Hosseini; Neil C Henney; George E Barreto; Amirhossein Sahebkar
Journal:  Neural Regen Res       Date:  2022-08       Impact factor: 5.135

9.  Neuroprotective effect of arctigenin against neuroinflammation and oxidative stress induced by rotenone.

Authors:  Na Zhang; Deqiang Dou; Xiaoku Ran; Tingguo Kang
Journal:  RSC Adv       Date:  2018-01-10       Impact factor: 4.036

Review 10.  Moving towards Integrated and Personalized Care in Parkinson's Disease: A Framework Proposal for Training Parkinson Nurses.

Authors:  Marlena van Munster; Johanne Stümpel; Franziska Thieken; David J Pedrosa; Angelo Antonini; Diane Côté; Margherita Fabbri; Joaquim J Ferreira; Evžen Růžička; David Grimes; Tiago A Mestre
Journal:  J Pers Med       Date:  2021-06-30
  10 in total

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