Literature DB >> 26526696

All the World's a Stage: Facilitating Discovery Science and Improved Cancer Care through the Global Alliance for Genomics and Health.

Mark Lawler1, Lillian L Siu2, Heidi L Rehm3, Stephen J Chanock4, Gil Alterovitz3, John Burn5, Fabien Calvo6, Denis Lacombe7, Bin Tean Teh8, Kathryn N North9, Charles L Sawyers10.   

Abstract

The recent explosion of genetic and clinical data generated from tumor genome analysis presents an unparalleled opportunity to enhance our understanding of cancer, but this opportunity is compromised by the reluctance of many in the scientific community to share datasets and the lack of interoperability between different data platforms. The Global Alliance for Genomics and Health is addressing these barriers and challenges through a cooperative framework that encourages "team science" and responsible data sharing, complemented by the development of a series of application program interfaces that link different data platforms, thus breaking down traditional silos and liberating the data to enable new discoveries and ultimately benefit patients. ©2015 American Association for Cancer Research.

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Year:  2015        PMID: 26526696     DOI: 10.1158/2159-8290.CD-15-0821

Source DB:  PubMed          Journal:  Cancer Discov        ISSN: 2159-8274            Impact factor:   39.397


  27 in total

Review 1.  Privacy challenges and research opportunities for genomic data sharing.

Authors:  Luca Bonomi; Yingxiang Huang; Lucila Ohno-Machado
Journal:  Nat Genet       Date:  2020-06-29       Impact factor: 38.330

Review 2.  Progress Toward Cancer Data Ecosystems.

Authors:  Robert L Grossman
Journal:  Cancer J       Date:  2018 May/Jun       Impact factor: 3.360

3.  Opportunities for Patient Matching Algorithms to Improve Patient Care in Oncology.

Authors:  Travis Johnson; David Liebner; James L Chen
Journal:  JCO Clin Cancer Inform       Date:  2017-11

Review 4.  Type 2 diabetes: genetic data sharing to advance complex disease research.

Authors:  Jason Flannick; Jose C Florez
Journal:  Nat Rev Genet       Date:  2016-07-11       Impact factor: 53.242

Review 5.  Genomics pipelines and data integration: challenges and opportunities in the research setting.

Authors:  Jeremy Davis-Turak; Sean M Courtney; E Starr Hazard; W Bailey Glen; Willian A da Silveira; Timothy Wesselman; Larry P Harbin; Bethany J Wolf; Dongjun Chung; Gary Hardiman
Journal:  Expert Rev Mol Diagn       Date:  2017-01-25       Impact factor: 5.225

6.  High-depth whole genome sequencing of an Ashkenazi Jewish reference panel: enhancing sensitivity, accuracy, and imputation.

Authors:  Todd Lencz; Jin Yu; Cameron Palmer; Shai Carmi; Danny Ben-Avraham; Nir Barzilai; Susan Bressman; Ariel Darvasi; Judy H Cho; Lorraine N Clark; Zeynep H Gümüş; Vijai Joseph; Robert Klein; Steven Lipkin; Kenneth Offit; Harry Ostrer; Laurie J Ozelius; Inga Peter; Gil Atzmon; Itsik Pe'er
Journal:  Hum Genet       Date:  2018-04-28       Impact factor: 4.132

Review 7.  Sharing Data to Build a Medical Information Commons: From Bermuda to the Global Alliance.

Authors:  Robert Cook-Deegan; Rachel A Ankeny; Kathryn Maxson Jones
Journal:  Annu Rev Genomics Hum Genet       Date:  2017-04-17       Impact factor: 8.929

8.  Genetics of multifactorial disorders: proceedings of the 6th Pan Arab Human Genetics Conference.

Authors:  Pratibha Nair; Sami Bizzari; Nirmal Rajah; Nada Assaf; Mahmoud Taleb Al-Ali; Abdul Rezzak Hamzeh
Journal:  J Transl Med       Date:  2016-04-20       Impact factor: 5.531

9.  Facilitating a culture of responsible and effective sharing of cancer genome data.

Authors:  Lillian L Siu; Mark Lawler; David Haussler; Bartha Maria Knoppers; Jeremy Lewin; Daniel J Vis; Rachel G Liao; Fabrice Andre; Ian Banks; J Carl Barrett; Carlos Caldas; Anamaria Aranha Camargo; Rebecca C Fitzgerald; Mao Mao; John E Mattison; William Pao; William R Sellers; Patrick Sullivan; Bin Tean Teh; Robyn L Ward; Jean Claude ZenKlusen; Charles L Sawyers; Emile E Voest
Journal:  Nat Med       Date:  2016-05-05       Impact factor: 53.440

Review 10.  Next-Generation Sequencing and the Clinical Oncology Workflow: Data Challenges, Proposed Solutions, and a Call to Action.

Authors:  Jake R Conway; Jeremy L Warner; Wendy S Rubinstein; Robert S Miller
Journal:  JCO Precis Oncol       Date:  2019-10-01
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