Literature DB >> 26525340

Sex and Gender Impact Immune Responses to Vaccines Among the Elderly.

Ashley L Fink1, Sabra L Klein2.   

Abstract

In response to the recommended vaccines in older-aged individuals, sex differences occur in response to those that protect against influenza, tetanus, pertussis, shingles, and pneumococcal infections. The efficacy of vaccines recommended for older-aged adults is consistently greater for females than for males. Gender differences as well as biological sex differences can influence vaccine uptake, responses, and outcome in older-aged individuals, which should influence guidelines, formulations, and dosage recommendations for vaccines in the elderly. ©2015 Int. Union Physiol. Sci./Am. Physiol. Soc.

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Year:  2015        PMID： 26525340      PMCID： PMC4630198          DOI： 10.1152/physiol.00035.2015

Source DB:  PubMed          Journal:  Physiology (Bethesda)        ISSN： 1548-9221


  111 in total

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Journal:  Vaccine       Date:  2007-09-14       Impact factor: 3.641

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Journal:  J Am Geriatr Soc       Date:  2009-06-08       Impact factor: 5.562

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  42 in total

Review 1.  Progesterone-based compounds affect immune responses and susceptibility to infections at diverse mucosal sites.

Authors:  Olivia J Hall; Sabra L Klein
Journal:  Mucosal Immunol       Date:  2017-04-12       Impact factor: 7.313

2.  Isolation and characterization of new human carrier peptides from two important vaccine immunogens.

Authors:  Paeton L Wantuch; Lina Sun; Rachel K LoPilato; Jarrod J Mousa; Robert S Haltiwanger; Fikri Y Avci
Journal:  Vaccine       Date:  2020-01-28       Impact factor: 3.641

3.  Impaired innate, humoral, and cellular immunity despite a take in smallpox vaccine recipients.

Authors:  Richard B Kennedy; Gregory A Poland; Inna G Ovsyannikova; Ann L Oberg; Yan W Asmann; Diane E Grill; Robert A Vierkant; Robert M Jacobson
Journal:  Vaccine       Date:  2016-05-11       Impact factor: 3.641

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Authors:  Lucy Denly
Journal:  Hum Vaccin Immunother       Date:  2020-11-12       Impact factor: 3.452

5.  Age and testosterone mediate influenza pathogenesis in male mice.

Authors:  Landon G Vom Steeg; Meghan S Vermillion; Olivia J Hall; Ornob Alam; Ross McFarland; Haolin Chen; Barry Zirkin; Sabra L Klein
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Authors:  Ashley L Fink; Sabra L Klein
Journal:  Curr Opin Physiol       Date:  2018-03-29

Review 7.  Innate immune responses in the ageing lung.

Authors:  D M Boe; L A Boule; E J Kovacs
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8.  Sex Differences and COVID-19.

Authors:  Natalie Thomas; Caroline Gurvich; Jayashri Kulkarni
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

9.  Sex- and Gender-Based Pharmacological Response to Drugs.

Authors:  Franck Mauvais-Jarvis; Heiner K Berthold; Ilaria Campesi; Juan-Jesus Carrero; Santosh Dakal; Flavia Franconi; Ioanna Gouni-Berthold; Mark L Heiman; Alexandra Kautzky-Willer; Sabra L Klein; Anne Murphy; Vera Regitz-Zagrosek; Karen Reue; Joshua B Rubin
Journal:  Pharmacol Rev       Date:  2021-04       Impact factor: 25.468

10.  The Possible Role of Sex As an Important Factor in Development and Administration of Lipid Nanomedicine-Based COVID-19 Vaccine.

Authors:  Elisabetta Vulpis; Francesca Giulimondi; Luca Digiacomo; Alessandra Zingoni; Reihaneh Safavi-Sohi; Shahriar Sharifi; Giulio Caracciolo; Morteza Mahmoudi
Journal:  Mol Pharm       Date:  2021-05-13       Impact factor: 4.939
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