Bimlesh Kumar1, Amit Upadhyay, Sunil Gothwal, Vijay Jaiswal, Payas Joshi, Kirti Dubey. 1. Departments of Pediatrics and Obstetrics, LLRM Medical College, Meerut, UP; and *Department of Pediatrics, SMS Medical College, Jaipur, Rajasthan; India. Correspondence to: Dr Amit Upadhyay, Department of Pediatrics, LLRM Medical College, Meerut, India. au.llrm@gmail.com.
Abstract
OBJECTIVE: To investigate the effect of umbilical cord milking on hematological parameters at 6 weeks of age in late preterm neonates. DESIGN: Randomized controlled trial. SETTING:A tertiary care center of Northern India during 2013-14. PARTICIPANTS: 200 moderate to late preterm neonates randomly allocated toearly cord clamping or umbilical cord milking group (100 in each). INTERVENTION: In milking group, 25 cm length of cord was milked towards the baby thrice after separating (within 30 s) it from placenta. MAIN OUTCOME MEASURES: Hemoglobin and serum ferritin at 6 weeks of age. RESULTS:Mean (SD) serum ferritin [428.9 (217.6) vs. 237.5 (118.6) ng/mL; P< 0.01] and hemoglobin [12.1 (1.5) vs. 10.4 (1.2) gm/dL; P<0.01] at 6 weeks were significantly higher in umbilical cord milking group. In early neonatal period, hemodynamic and hematological parameters were not significantly different. Higher incidence of jaundice with higher phototherapy rates (33% vs. 9%; P<0.01) were noted in umbilical cord milking group. CONCLUSIONS: In preterm neonates, umbilical cord milking at birth enhances iron stores at 6 weeks of age. Higher phototherapy rates with this intervention are a matter of concern.
RCT Entities:
OBJECTIVE: To investigate the effect of umbilical cord milking on hematological parameters at 6 weeks of age in late preterm neonates. DESIGN: Randomized controlled trial. SETTING: A tertiary care center of Northern India during 2013-14. PARTICIPANTS: 200 moderate to late preterm neonates randomly allocated to early cord clamping or umbilical cord milking group (100 in each). INTERVENTION: In milking group, 25 cm length of cord was milked towards the baby thrice after separating (within 30 s) it from placenta. MAIN OUTCOME MEASURES: Hemoglobin and serum ferritin at 6 weeks of age. RESULTS: Mean (SD) serum ferritin [428.9 (217.6) vs. 237.5 (118.6) ng/mL; P< 0.01] and hemoglobin [12.1 (1.5) vs. 10.4 (1.2) gm/dL; P<0.01] at 6 weeks were significantly higher in umbilical cord milking group. In early neonatal period, hemodynamic and hematological parameters were not significantly different. Higher incidence of jaundice with higher phototherapy rates (33% vs. 9%; P<0.01) were noted in umbilical cord milking group. CONCLUSIONS: In preterm neonates, umbilical cord milking at birth enhances iron stores at 6 weeks of age. Higher phototherapy rates with this intervention are a matter of concern.
Authors: Bikramjit Das; Venkataseshan Sundaram; Praveen Kumar; William T Mordi; Lakhbir K Dhaliwal; Reena Das Journal: Indian J Pediatr Date: 2017-11-04 Impact factor: 1.967
Authors: Judith S Mercer; Debra A Erickson-Owens; Sean C L Deoni; Douglas C Dean; Jennifer Collins; Ashley B Parker; Meijia Wang; Sarah Joelson; Emily N Mercer; James F Padbury Journal: J Pediatr Date: 2018-07-06 Impact factor: 6.314