Literature DB >> 26519273

Association of Flavin Monooxygenase Gene E158K Polymorphism with Chronic Heart Disease Risk.

O Yu Bushueva1, I V Bulgakova2, V P Ivanov2, A V Polonikov2.   

Abstract

We studied the relationship between the risk of chronic heart disease and FMO3 gene polymorphism E158K analyzed by PCR and restriction fragment length polymorphism (RFLP) analysis. The homozygous 158KK genotype of FMO3 gene is associated with high risk of chronic heart disease in women, but not in men. FMO3 gene polymorphism E158K is a significant predictor of predisposition to chronic heart disease in women.

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Keywords:  association; chronic heart disease; flavin-containing monooxygenase 3

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Year:  2015        PMID: 26519273     DOI: 10.1007/s10517-015-3073-8

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN: 0007-4888            Impact factor:   0.804


  1 in total

1.  Trimethylamine N-oxide promotes atherosclerosis via regulating the enriched abundant transcript 1/miR-370-3p/signal transducer and activator of transcription 3/flavin-containing monooxygenase-3 axis.

Authors:  Aijun Liu; Yonglin Zhang; Shucan Xun; Minli Sun
Journal:  Bioengineered       Date:  2022-01       Impact factor: 6.832

  1 in total

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