Literature DB >> 2651919

Polymorphism of a 35-48 kDa Plasmodium falciparum merozoite surface antigen.

B Fenton1, J T Clark, C F Wilson, J S McBride, D Walliker.   

Abstract

Glycoproteins of the asexual blood stages of Plasmodium falciparum were labelled with radioactive glucosamine and analysed by two-dimensional electrophoresis. Four major glycoproteins were detected in all eight parasite isolates studied. Two of the glycoproteins, designated GP2 and GP4, were invariant among the isolates, while the other two GP1 and GP3 were found to be polymorphic in both their biochemical and antigenic properties. By immunoblotting and immunoprecipitation with specific monoclonal antibodies, the two polymorphic glycoproteins were identified as surface antigens of merozoites.

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Year:  1989        PMID： 2651919     DOI： 10.1016/0166-6851(89)90022-4

Source DB:  PubMed          Journal:  Mol Biochem Parasitol        ISSN： 0166-6851            Impact factor:   1.759


  12 in total

1.  Structural and antigenic polymorphism of the 35- to 48-kilodalton merozoite surface antigen (MSA-2) of the malaria parasite Plasmodium falciparum.

Authors:  B Fenton; J T Clark; C M Khan; J V Robinson; D Walliker; R Ridley; J G Scaife; J S McBride
Journal:  Mol Cell Biol       Date:  1991-02       Impact factor: 4.272

2.  Antibodies to a conserved-motif peptide sequence of the Plasmodium falciparum thrombospondin-related anonymous protein and circumsporozoite protein recognize a 78-kilodalton protein in the asexual blood stages of the parasite and inhibit merozoite invasion in vitro.

Authors:  P Sharma; A Bharadwaj; V K Bhasin; V N Sailaja; V S Chauhan
Journal:  Infect Immun       Date:  1996-06       Impact factor: 3.441

Review 3.  Glycobiology of Plasmodium falciparum: an emerging area of research.

Authors:  D C Hoessli; E A Davidson; R T Schwarz
Journal:  Glycoconj J       Date:  1996-02       Impact factor: 2.916

4.  Identification of key residues involved in fibril formation by the conserved N-terminal region of Plasmodium falciparum merozoite surface protein 2 (MSP2).

Authors:  Xiaodong Yang; Christopher G Adda; Christopher A MacRaild; Andrew Low; Xuecheng Zhang; Weiguang Zeng; David C Jackson; Robin F Anders; Raymond S Norton
Journal:  Biochimie       Date:  2010-06-11       Impact factor: 4.079

5.  Structural diversity in the Plasmodium falciparum merozoite surface antigen 2.

Authors:  J A Smythe; R L Coppel; K P Day; R K Martin; A M Oduola; D J Kemp; R F Anders
Journal:  Proc Natl Acad Sci U S A       Date:  1991-03-01       Impact factor: 11.205

6.  Acquired antibodies to merozoite antigens in children from Uganda with uncomplicated or severe Plasmodium falciparum malaria.

Authors:  Hodan Ahmed Ismail; Ulf Ribacke; Linda Reiling; Johan Normark; Tom Egwang; Fred Kironde; James G Beeson; Mats Wahlgren; Kristina E M Persson
Journal:  Clin Vaccine Immunol       Date:  2013-06-05

7.  A second merozoite surface protein (MSP-4) of Plasmodium falciparum that contains an epidermal growth factor-like domain.

Authors:  V M Marshall; A Silva; M Foley; S Cranmer; L Wang; D J McColl; D J Kemp; R L Coppel
Journal:  Infect Immun       Date:  1997-11       Impact factor: 3.441

Review 8.  In vitro models for human malaria: targeting the liver stage.

Authors:  Ana Lisa Valenciano; Maria G Gomez-Lorenzo; Joel Vega-Rodríguez; John H Adams; Alison Roth
Journal:  Trends Parasitol       Date:  2022-06-30

9.  Genetic diversity of Plasmodium falciparum field isolates from south western Nigeria.

Authors:  G I Olasehinde; C S Yah; R Singh; O Olusola Ojuronbge; A A Ajayi; N Valecha; A O Abolaji; A O Adeyeba
Journal:  Afr Health Sci       Date:  2012-09       Impact factor: 0.927

10.  A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum.

Authors:  Alison Roth; Steven P Maher; Amy J Conway; Ratawan Ubalee; Victor Chaumeau; Chiara Andolina; Stephen A Kaba; Amélie Vantaux; Malina A Bakowski; Richard Thomson-Luque; Swamy Rakesh Adapa; Naresh Singh; Samantha J Barnes; Caitlin A Cooper; Mélanie Rouillier; Case W McNamara; Sebastian A Mikolajczak; Noah Sather; Benoît Witkowski; Brice Campo; Stefan H I Kappe; David E Lanar; François Nosten; Silas Davidson; Rays H Y Jiang; Dennis E Kyle; John H Adams
Journal:  Nat Commun       Date:  2018-05-09       Impact factor: 14.919
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