Literature DB >> 26516669

Changing Patterns of Organ Donation: Brain Dead Donors Are Not Being Lost by Donation After Circulatory Death.

Helen M Nelson1, Alexandra K Glazier, Francis L Delmonico.   

Abstract

The clinical characteristics of all New England Organ Bank (NEOB) donors after circulatory death (DCD) donors were analyzed between July 1, 2009, and June 30, 2014. During that 5-year period, there were 494 authorized medically suitable potential DCDs that the NEOB evaluated, constituting more than 30% of deceased donors coordinated annually by the NEOB. From the cohort of 494 authorized potential DCDs, 331 (67%) became actual DCD, 82 (17%) were attempted as a DCD but did not progress to donation, and 81 (16%) transitioned to an actual donor after brain death (DBD). Two hundred seventy-six organs were transplanted from the 81 donors that transitioned from DCD to actual DBD, including 24 heart, 70 liver, 12 single and 14 bilateral lung, and 12 pancreas transplants. When patients with devastating brain injury admitted to the intensive care units are registered donors, the Organ Procurement Organization staff should share the patient's donation decision with the health care team and the patient's family, as early as possible after the comfort measures only discussion has been initiated. The experience of the NEOB becomes an important reference of the successful implementation of DCD that enables an expansion of deceased donation (inclusive of DBD).

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Year:  2016        PMID: 26516669     DOI: 10.1097/TP.0000000000000954

Source DB:  PubMed          Journal:  Transplantation        ISSN: 0041-1337            Impact factor:   4.939


  5 in total

1.  Wide variation in the percentage of donation after circulatory death donors across donor service areas - a potential target for improvement.

Authors:  Elizabeth M Sonnenberg; Jesse Y Hsu; Peter P Reese; David Goldberg; Peter L Abt
Journal:  Transplantation       Date:  2019-10-21       Impact factor: 4.939

2.  Discarded Livers Find a New Life: Engineered Liver Grafts Using Hepatocytes Recovered From Marginal Livers.

Authors:  Basak E Uygun; Maria-Louisa Izamis; Maria Jaramillo; Yibin Chen; Gavrielle Price; Sinan Ozer; Martin L Yarmush
Journal:  Artif Organs       Date:  2016-11-08       Impact factor: 3.094

Review 3.  Organ donation after circulatory death: current status and future potential.

Authors:  Martin Smith; B Dominguez-Gil; D M Greer; A R Manara; M J Souter
Journal:  Intensive Care Med       Date:  2019-02-06       Impact factor: 17.440

4.  Wide Variation in the Percentage of Donation After Circulatory Death Donors Across Donor Service Areas: A Potential Target for Improvement.

Authors:  Elizabeth M Sonnenberg; Jesse Y Hsu; Peter P Reese; David S Goldberg; Peter L Abt
Journal:  Transplantation       Date:  2020-08       Impact factor: 5.385

5.  Deceased organ donation for transplantation: Challenges and opportunities.

Authors:  Raffaele Girlanda
Journal:  World J Transplant       Date:  2016-09-24
  5 in total

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