Literature DB >> 26515472

Prepregnancy Obesity and Birth Outcomes.

Susan L Averett1, Erin K Fletcher2.   

Abstract

OBJECTIVE: To investigate the association between prepregnancy obesity and birth outcomes using fixed effect models comparing siblings from the same mother.
METHODS: A total of 7496 births to 3990 mothers from the National Longitudinal Survey of Youth 1979 survey are examined. Outcomes include macrosomia, gestational length, incidence of low birthweight, preterm birth, large and small for gestational age (LGA, SGA), c-section, infant doctor visits, mother's and infant's days in hospital post-partum, whether the mother breastfed, and duration of breastfeeding. Association of outcomes with maternal pre-pregnancy obesity was examined using Ordinary Least Squares (OLS) regression to compare across mothers and fixed effects to compare within families.
RESULTS: In fixed effect models we find no statistically significant association between most outcomes and prepregnancy obesity with the exception of LGA, SGA, low birth weight, and preterm birth. We find that prepregnancy obesity is associated with a with lower risk of low birthweight, SGA, and preterm birth but controlling for prepregnancy obesity, increases in GWG lead to increased risk of LGA.
CONCLUSIONS: Contrary to previous studies, which have found that maternal obesity increases the risk of c-section, macrosomia, and LGA, while decreasing the probability of breastfeeding, our sibling comparison models reveal no such association. In fact, our results suggest a protective effect of obesity in that women who are obese prepregnancy have longer gestation lengths, and are less likely to give birth to a preterm or low birthweight infant.

Entities:  

Keywords:  BMI; Birth outcomes; Gestational weight gain; Infant health; Maternal obesity

Mesh:

Year:  2016        PMID: 26515472     DOI: 10.1007/s10995-015-1865-0

Source DB:  PubMed          Journal:  Matern Child Health J        ISSN: 1092-7875


  28 in total

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2.  The effect of the increasing prevalence of maternal obesity on perinatal morbidity.

Authors:  G C Lu; D J Rouse; M DuBard; S Cliver; D Kimberlin; J C Hauth
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Review 5.  Systematic literature review of the costs of pregnancy in the US.

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6.  Associations of maternal pre-pregnancy obesity and excess pregnancy weight gains with adverse pregnancy outcomes and length of hospital stay.

Authors:  Abdullah A Mamun; Leonie K Callaway; Michael J O'Callaghan; Gail M Williams; Jake M Najman; Rosa Alati; Alexandra Clavarino; Debbie A Lawlor
Journal:  BMC Pregnancy Childbirth       Date:  2011-09-06       Impact factor: 3.007

7.  The impact of prepregnancy obesity on children's cognitive test scores.

Authors:  Rika Tanda; Pamela J Salsberry; Patricia B Reagan; Muriel Z Fang
Journal:  Matern Child Health J       Date:  2013-02

8.  The influence of obesity and diabetes on the prevalence of macrosomia.

Authors:  Hugh M Ehrenberg; Brian M Mercer; Patrick M Catalano
Journal:  Am J Obstet Gynecol       Date:  2004-09       Impact factor: 8.661

9.  Combined associations of prepregnancy body mass index and gestational weight gain with the outcome of pregnancy.

Authors:  Ellen A Nohr; Michael Vaeth; Jennifer L Baker; Thorkild Ia Sørensen; Jorn Olsen; Kathleen M Rasmussen
Journal:  Am J Clin Nutr       Date:  2008-06       Impact factor: 7.045

Review 10.  Pre-pregnancy body mass index in relation to infant birth weight and offspring overweight/obesity: a systematic review and meta-analysis.

Authors:  Zhangbin Yu; Shuping Han; Jingai Zhu; Xiaofan Sun; Chenbo Ji; Xirong Guo
Journal:  PLoS One       Date:  2013-04-16       Impact factor: 3.240

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2.  Body Mass Index as a Measure of Obesity: Racial Differences in Predictive Value for Health Parameters During Pregnancy.

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Journal:  J Womens Health (Larchmt)       Date:  2016-08-03       Impact factor: 2.681

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4.  Prepregnancy Overweight and Obesity Are Associated with an Increased Risk of Preterm Birth in Chinese Women.

Authors:  Xiu Juan Su; Shi Jia Huang; Xiang Li; Qiao Ling Du
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5.  Genome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth.

Authors:  Xiumei Hong; Ke Hao; Hongkai Ji; Shouneng Peng; Ben Sherwood; Antonio Di Narzo; Hui-Ju Tsai; Xin Liu; Irina Burd; Guoying Wang; Yuelong Ji; Deanna Caruso; Guangyun Mao; Tami R Bartell; Zhongyang Zhang; Colleen Pearson; Linda Heffner; Sandra Cerda; Terri H Beaty; M Daniele Fallin; Aviva Lee-Parritz; Barry Zuckerman; Daniel E Weeks; Xiaobin Wang
Journal:  Nat Commun       Date:  2017-06-09       Impact factor: 14.919

6.  Nausea, vomiting and poor appetite during pregnancy and adverse birth outcomes in rural Nepal: an observational cohort study.

Authors:  Amanda Regodón Wallin; James M Tielsch; Subarna K Khatry; Luke C Mullany; Janet A Englund; Helen Chu; Steven C LeClerq; Joanne Katz
Journal:  BMC Pregnancy Childbirth       Date:  2020-09-17       Impact factor: 3.007

7.  Assessing the relationship between pregravid body mass index and risk of adverse maternal pregnancy and neonatal outcomes: prospective data in Southwest China.

Authors:  Yue Chen; Ke Wan; Yunhui Gong; Xiao Zhang; Yi Liang; Xiaoyu Wang; Ping Feng; Fang He; Rong Zhou; Dagang Yang; Hong Jia; Guo Cheng; Toshio Shimokawa
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8.  Impact of body weight on the outcome of pregnancy: A prospective cohort study.

Authors:  Ettedal A Aljahdali
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  8 in total

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