Lyn M Balsamo1, Kyaw J Sint2, Joseph P Neglia3, Pim Brouwers4, Nina S Kadan-Lottick5. 1. Section of Pediatric Hematology/Oncology, Yale University School of Medicine lyn.balsamo@yale.edu. 2. School of Public Health, Yale University. 3. University of Minnesota Medical School. 4. National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA. 5. Section of Pediatric Hematology/Oncology, Yale University School of Medicine Yale Comprehensive Cancer Center, New Haven, CT, USA.
Abstract
OBJECTIVE: Assess the association between fine motor (FM) and visual-motor integration (VMI) skills and academic achievement in pediatric acute lymphoblastic leukemia (ALL) survivors. METHODS: In this 28-site cross-sectional study of 256 children in first remission, a mean of 8.9 ± 2.2 years after treatment for standard-risk precursor-B ALL, validated measures of FM, VMI, reading, math, and intelligence were administered at mean follow-up age of 12.8 ± 2.5 years. RESULTS: VMI was significantly associated with written math calculation ability (p < .0069) after adjusting for intelligence (p < .0001). VMI was more strongly associated with math in those with lower intelligence (p = .0141). Word decoding was also significantly associated with VMI but with no effect modification by intelligence. FM skills were not associated with either reading or math achievement. CONCLUSION: These findings suggest that VMI is associated with aspects of math and reading achievement in leukemia survivors. These skills may be amenable to intervention.
OBJECTIVE: Assess the association between fine motor (FM) and visual-motor integration (VMI) skills and academic achievement in pediatric acute lymphoblastic leukemia (ALL) survivors. METHODS: In this 28-site cross-sectional study of 256 children in first remission, a mean of 8.9 ± 2.2 years after treatment for standard-risk precursor-B ALL, validated measures of FM, VMI, reading, math, and intelligence were administered at mean follow-up age of 12.8 ± 2.5 years. RESULTS: VMI was significantly associated with written math calculation ability (p < .0069) after adjusting for intelligence (p < .0001). VMI was more strongly associated with math in those with lower intelligence (p = .0141). Word decoding was also significantly associated with VMI but with no effect modification by intelligence. FM skills were not associated with either reading or math achievement. CONCLUSION: These findings suggest that VMI is associated with aspects of math and reading achievement in leukemia survivors. These skills may be amenable to intervention.
Authors: R T Brown; M B Sawyer; G Antoniou; I Toogood; M Rice; N Thompson; A Madan-Swain Journal: J Dev Behav Pediatr Date: 1996-12 Impact factor: 2.225
Authors: Annemieke I Buizer; Leo M J De Sonneville; Marry M van den Heuvel-Eibrink; Charles Njiokiktjien; Anjo J P Veerman Journal: J Int Neuropsychol Soc Date: 2005-09 Impact factor: 2.892