Literature DB >> 26513715

Effect of Continued Medical Therapy on Productivity Costs for Refractory Chronic Rhinosinusitis.

Luke Rudmik1, Zachary M Soler2, Timothy L Smith3, Jess C Mace3, Rodney J Schlosser2, Adam S DeConde4.   

Abstract

IMPORTANCE: It is estimated that lost productivity related to chronic rhinosinusitis (CRS) costs society in excess of $13 billion per year in the United States. Given this tremendous cost to society, it is important to evaluate the effect of current interventions on improving this productivity loss.
OBJECTIVE: To define the change in productivity costs in patients with refractory CRS who select continued medical therapy. DESIGN, SETTING, AND PARTICIPANTS: Observational cohort study. Thirty-eight patients with a guideline-based diagnosis of CRS whose initial appropriate medical therapy failed were enrolled from 4 tertiary-level rhinology clinics. The study was conducted from December 6, 2010, to April 23, 2013, and data analysis was performed from December 6, 2010, to June 1, 2015.
INTERVENTIONS: Continued medical therapy for CRS. MAIN OUTCOMES AND MEASURES: The human capital approach was applied to quantify productivity costs. Absenteeism, presenteeism, and lost leisure time were quantified to define annual lost productive time, which was measured at enrollment (baseline) and at a minimum of 6 months after treatment. Lost productive time was monetized using the annual daily wage rates obtained from the 2012 US National Census and the 2013 US Department of Labor statistics.
RESULTS: Thirty-eight patients with refractory CRS who selected continued medical therapy had a mean (SD) baseline annual productivity cost of $3464 ($4900) per patient. After continued medical therapy for a mean of 12.8 (4.8) months, productivity costs were $2730 ($3720) (before vs after continued medical therapy productivity cost, P = .74). Mean annual absenteeism was reduced from 5 (12) days to 2 (8) days (P = .02). Mean annual presenteeism (17 [27] days reduced to 15 [23] days; P = .93) and mean annual household days lost (7 [7] days reduced to 6 [6] days; P = .51) were maintained at baseline levels. There were no significant differences in productivity outcomes based on endoscopy, the 22-item Sinonasal Outcome Test score, age, or polyp status (all P ≥ .11). CONCLUSIONS AND RELEVANCE: Patients with refractory CRS often make treatment decisions based on the degree of quality-of-life and productivity impairment. Outcomes from this study suggest that productivity in patients with refractory CRS who have minor reductions in baseline productivity can remain stable with continued medical therapy. Physicians can use this information to inform appropriate patients with CRS of their expected outcomes from continued medical therapy.

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Year:  2015        PMID: 26513715     DOI: 10.1001/jamaoto.2015.2321

Source DB:  PubMed          Journal:  JAMA Otolaryngol Head Neck Surg        ISSN: 2168-6181            Impact factor:   6.223


  10 in total

1.  Productivity changes following medical and surgical treatment of chronic rhinosinusitis by symptom domain.

Authors:  Daniel M Beswick; Jess C Mace; Luke Rudmik; Zachary M Soler; Adam S DeConde; Timothy L Smith
Journal:  Int Forum Allergy Rhinol       Date:  2018-07-28       Impact factor: 3.858

Review 2.  Economics of Chronic Rhinosinusitis.

Authors:  Luke Rudmik
Journal:  Curr Allergy Asthma Rep       Date:  2017-04       Impact factor: 4.806

3.  Socioeconomic status impacts postoperative productivity loss and health utility changes in refractory chronic rhinosinusitis.

Authors:  Daniel M Beswick; Jess C Mace; Zachary M Soler; Luke Rudmik; Jeremiah A Alt; Kristine A Smith; Kara Y Detwiller; Vijay R Ramakrishnan; Timothy L Smith
Journal:  Int Forum Allergy Rhinol       Date:  2019-06-27       Impact factor: 3.858

Review 4.  A role for auto-immunity in chronic rhinosinusitis? Lessons learned from sub-epidermal bullous disorders of the skin.

Authors:  Philippe Lefrançois; Hugo Chapdelaine; Benoît Côté; Martin Desrosiers
Journal:  Allergy Asthma Clin Immunol       Date:  2016-08-05       Impact factor: 3.406

5.  Clinical predictors of chronic rhinosinusitis: do the Canadian clinical practice guidelines for acute and chronic rhinosinusitis predict CT-confirmation of disease?

Authors:  Paige Moore; Brian Blakley; Eric Meen
Journal:  J Otolaryngol Head Neck Surg       Date:  2017-12-04

6.  Resection versus preservation of the middle turbinate in surgery for chronic rhinosinusitis with nasal polyposis: a randomized controlled trial.

Authors:  Marc-Antoine Hudon; Erin D Wright; Etienne Fortin-Pellerin; Marie Bussieres
Journal:  J Otolaryngol Head Neck Surg       Date:  2018-11-08

7.  Impact of Cystic Fibrosis Transmembrane Conductance Regulator Therapy on Chronic Rhinosinusitis and Health Status: Deep Learning CT Analysis and Patient-reported Outcomes.

Authors:  Daniel M Beswick; Stephen M Humphries; Connor D Balkissoon; Matthew Strand; Eszter K Vladar; David A Lynch; Jennifer L Taylor-Cousar
Journal:  Ann Am Thorac Soc       Date:  2022-01

Review 8.  Biologics for severe uncontrolled chronic rhinosinusitis with nasal polyps: a change management approach. Consensus of the Joint Committee of Italian Society of Otorhinolaryngology on biologics in rhinology.

Authors:  Eugenio De Corso; Gianluca Bellocchi; Michele De Benedetto; Nicola Lombardo; Alberto Macchi; Luca Malvezzi; Gaetano Motta; Fabio Pagella; Claudio Vicini; Desiderio Passali
Journal:  Acta Otorhinolaryngol Ital       Date:  2021-07-23       Impact factor: 2.618

Review 9.  Clinical Research Needs for the Management of Chronic Rhinosinusitis with Nasal Polyps in the New Era of Biologics: A National Institute of Allergy and Infectious Diseases Workshop.

Authors:  Robert Naclerio; Fuad Baroody; Claus Bachert; Benjamin Bleier; Larry Borish; Erica Brittain; Geoffrey Chupp; Anat Fisher; Wytske Fokkens; Philippe Gevaert; David Kennedy; Jean Kim; Tanya M Laidlaw; Jake J Lee; Jay F Piccirillo; Jayant M Pinto; Lauren T Roland; Robert P Schleimer; Rodney J Schlosser; Julie M Schwaninger; Timothy L Smith; Bruce K Tan; Ming Tan; Elina Toskala; Sally Wenzel; Alkis Togias
Journal:  J Allergy Clin Immunol Pract       Date:  2020-03-04

Review 10.  The value of endoscopic sinus surgery in chronic rhinosinusitis.

Authors:  Michael T Yim; Kristine A Smith; Jeremiah A Alt; Richard R Orlandi
Journal:  Laryngoscope Investig Otolaryngol       Date:  2021-01-23
  10 in total

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