Literature DB >> 26512341

Nonoperative Management of a Multi-Regional Epidural Abscess with Neurological Dysfunction.

Maire-Clare Killen1, Miguel Hernandez1, Andrew Berg2, Chandra Bhatia1.   

Abstract

Spinal epidural abscesses are uncommon, but their incidence is increasing. They represent a collection of purulent material in the epidural space and most commonly occur in the lumbar spine, where they remain localised. Abscesses that affect all three spinal levels (holospinal or multiregional abscesses) are extremely rare, with only a few cases published in the literature. Epidural abscesses are particularly high risk infections as progressive neurological dysfunction can occur rapidly; early diagnosis and treatment is therefore essential to avoid long term neurological complications and reduce potential mortality. Given the uncommon nature of this condition, the treatment remains controversial with no definitive guidance on conservative versus surgical management. The literature mostly recommends surgical decompression along with intravenous antibiotics in patients with neurological abnormalities. We describe a case of a 77-year-old patient presenting with a delayed diagnosis of a multi-regional epidural abscess with associated upper motor neurone signs. The patient was successfully treated nonoperatively with a course of antibiotics resulting in complete radiological resolution of the abscess and full neurological recovery.

Entities:  

Keywords:  Epidural; abscess; multi-regional; nonoperative

Year:  2015        PMID: 26512341      PMCID: PMC4610323          DOI: 10.14444/2047

Source DB:  PubMed          Journal:  Int J Spine Surg        ISSN: 2211-4599


  26 in total

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Journal:  Spine J       Date:  2013-11-12       Impact factor: 4.166

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Authors:  Alexander Tuchman; Martin Pham; Patrick C Hsieh
Journal:  Neurosurg Focus       Date:  2014-08       Impact factor: 4.047

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Journal:  Radiology       Date:  1985-10       Impact factor: 11.105

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Authors:  Marc Tompkins; Ian Panuncialman; Phillip Lucas; Mark Palumbo
Journal:  J Emerg Med       Date:  2010-01-08       Impact factor: 1.484

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  3 in total

1.  Surgical management of an extensive spinal epidural abscess: illustrative cases.

Authors:  Aleksey Eroshkin; Dmytro Romanukha; Serhiy Voitsekhovskyi
Journal:  J Neurosurg Case Lessons       Date:  2021-01-11

2.  Primary Spinal Epidural Abscesses Not Associated With Pyogenic Infectious Spondylodiscitis: A New Pathogenetic Hypothesis.

Authors:  Lorenzo Magrassi; Marco Mussa; Andrea Montalbetti; Marta Colaneri; Angela di Matteo; Antonello Malfitano; Anna Maria Simoncelli; Maria Grazia Egitto; Claudio Bernucci; Enrico Brunetti
Journal:  Front Surg       Date:  2020-04-30

3.  Skip hemilaminectomy for the treatment of holospinal epidural abscess: A single-center experience.

Authors:  Alessandro Di Rienzo; Riccardo Paracino; Valentina Liverotti; Maurizio Gladi; Mauro Dobran
Journal:  Surg Neurol Int       Date:  2021-12-30
  3 in total

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