Literature DB >> 26512307

Photoletter to the editor: Topical 0.5% brimonidine gel to camouflage redness of immature scars.

Markus Reinholz1, Markus Heppt1, Julia K Tietze1, Thomas Ruzicka1, Gerd G Gauglitz1, Jürgen Schauber1.   

Abstract

Cutaneous scars develop as a result of a defective wound healing process. Scars are commonly visible as erythematous, sometimes disfiguring lesions which might be stigmatizing for the affected patient. Only a few therapies to improve the appearance of scars are available. Recently, brimonidine - a selective α2-receptor-agonist which causes vasoconstriction of small cutaneous vessels - was approved for the treatment of erythemato-telangiectatic rosacea. Topical brimonidine might also be helpful to improve redness of immature scars. Here we report on the effect of brimonidine 0.5% gel on a flat, erythematous scar in a 25-year-old female patient. Whitening of the scar could be observed immediately after application of brimonidine 0.5% gel and a good clinical result was observed within one hour. This effect lasted for up to three hours. We conclude that brimonidine 0.5% gel is a suitable topical therapy to reduce erythema in visible cutaneous scars.

Entities:  

Keywords:  brimonidine gel; erythema; immature scar; scar; topical therapy

Year:  2015        PMID: 26512307      PMCID: PMC4619167          DOI: 10.3315/jdcr.2015.1210

Source DB:  PubMed          Journal:  J Dermatol Case Rep        ISSN: 1898-7249


  5 in total

1.  Treatment of striae distensae using an ablative Erbium: YAG fractional laser versus a 585-nm pulsed-dye laser.

Authors:  Gerd G Gauglitz; Markus Reinholz; Peter Kaudewitz; Jürgen Schauber; Thomas Ruzicka
Journal:  J Cosmet Laser Ther       Date:  2013-11-18       Impact factor: 2.247

2.  German S2k guidelines for the therapy of pathological scars (hypertrophic scars and keloids).

Authors:  Alexander Nast; Sabine Eming; Joachim Fluhr; Klaus Fritz; Gerd Gauglitz; Silvia Hohenleutner; Renato G Panizzon; Günther Sebastian; Birte Sporbeck; Josef Koller
Journal:  J Dtsch Dermatol Ges       Date:  2012-09-03       Impact factor: 5.584

3.  Rosacea - S1 guideline.

Authors:  Markus Reinholz; Julia K Tietze; Katharina Kilian; Martin Schaller; Helmut Schöfer; Percy Lehmann; Manfred Zierhut; Winfried Klövekorn; Thomas Ruzicka; Jürgen Schauber
Journal:  J Dtsch Dermatol Ges       Date:  2013-05-06       Impact factor: 5.584

Review 4.  Updated international clinical recommendations on scar management: part 1--evaluating the evidence.

Authors:  Michael H Gold; Brian Berman; Matteo Tretti Clementoni; Gerd G Gauglitz; Foad Nahai; Crystal Murcia
Journal:  Dermatol Surg       Date:  2014-08       Impact factor: 3.398

5.  Efficacy and safety of once-daily topical brimonidine tartrate gel 0.5% for the treatment of moderate to severe facial erythema of rosacea: results of two randomized, double-blind, and vehicle-controlled pivotal studies.

Authors:  Joseph Fowler; Mark Jackson; Angela Moore; Michael Jarratt; Terry Jones; Kappa Meadows; Martin Steinhoff; Diane Rudisill; Matthew Leoni
Journal:  J Drugs Dermatol       Date:  2013-06-01       Impact factor: 2.114

  5 in total
  1 in total

Review 1.  [Postoperative care and options for scar treatment in eyelid surgery].

Authors:  M Keserü; S Dulz; A Wolf; S Green; U Press; U Schaudig
Journal:  Ophthalmologe       Date:  2018-04       Impact factor: 1.059

  1 in total

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