J W Yeates1. 1. RSPCA, Horsham, West Sussex, RH13 9RS.
Abstract
OBJECTIVES: To present insights to aid decision-making about novel veterinary treatments from regulations concerning animal experimentation and human clinical medical trials. MATERIALS AND METHODS: EU Directive 2010/63/EU on the protection of animals used for scientific purposes and EU Regulation 536/2014 on clinical trials on medicinal products for human use were analysed, evaluated and "translated" into relevant principles for veterinary surgeons. RESULTS: A number of principles are relevant, relating to treatment expectations, thresholds and objectives; client consent; minimising harms; personnel; review committees; assessment and publication. CLINICAL SIGNIFICANCE: These principles should assist veterinary surgeons to make good ethical decisions about novel treatments.
OBJECTIVES: To present insights to aid decision-making about novel veterinary treatments from regulations concerning animal experimentation and human clinical medical trials. MATERIALS AND METHODS: EU Directive 2010/63/EU on the protection of animals used for scientific purposes and EU Regulation 536/2014 on clinical trials on medicinal products for human use were analysed, evaluated and "translated" into relevant principles for veterinary surgeons. RESULTS: A number of principles are relevant, relating to treatment expectations, thresholds and objectives; client consent; minimising harms; personnel; review committees; assessment and publication. CLINICAL SIGNIFICANCE: These principles should assist veterinary surgeons to make good ethical decisions about novel treatments.
Authors: Alexandra Palmer; Beth Greenhough; Pru Hobson-West; Reuben Message; James N Aegerter; Zoe Belshaw; Ngaire Dennison; Roger Dickey; Julie Lane; Jamie Lorimer; Kate Millar; Chris Newman; Kirsten Pullen; S James Reynolds; Dominic J Wells; Matthew J Witt; Sarah Wolfensohn Journal: Animals (Basel) Date: 2020-10-13 Impact factor: 2.752