Literature DB >> 26504636

28 MHz swept source at 1.0 μm for ultrafast quantitative phase imaging.

Xiaoming Wei1, Andy K S Lau1, Yiqing Xu1, Kevin K Tsia1, Kenneth K Y Wong1.   

Abstract

Emerging high-throughput optical imaging modalities, in particular those providing phase information, necessitate a demanding speed regime (e.g. megahertz sweep rate) for those conventional swept sources; while an effective solution is yet to be demonstrated. We demonstrate a stable breathing laser as inertia-free swept source (BLISS) operating at a wavelength sweep rate of 28 MHz, particularly for the ultrafast interferometric imaging modality at 1.0 μm. Leveraging a tunable dispersion compensation element inside the laser cavity, the wavelength sweep range of BLISS can be tuned from ~10 nm to ~63 nm. It exhibits a good intensity stability, which is quantified by the ratio of standard deviation to the mean of the pulse intensity, i.e. 1.6%. Its excellent wavelength repeatability, <0.05% per sweep, enables the single-shot imaging at an ultrafast line-scan rate without averaging. To showcase its potential applications, it is applied to the ultrafast (28-MHz line-scan rate) interferometric time-stretch (iTS) microscope to provide quantitative morphological information on a biological specimen at a lateral resolution of 1.2 μm. This fiber-based inertia-free swept source is demonstrated to be robust and broadband, and can be applied to other established imaging modalities, such as optical coherence tomography (OCT), of which an axial resolution better than 12 μm can be achieved.

Keywords:  (110.3175) Interferometric imaging; (140.3615) Lasers, ytterbium; (140.4050) Mode-locked lasers

Year:  2015        PMID: 26504636      PMCID: PMC4605045          DOI: 10.1364/BOE.6.003855

Source DB:  PubMed          Journal:  Biomed Opt Express        ISSN: 2156-7085            Impact factor:   3.732


  30 in total

1.  Photonic crystal fibers.

Authors:  Philip Russell
Journal:  Science       Date:  2003-01-17       Impact factor: 47.728

2.  Multi-megahertz OCT: High quality 3D imaging at 20 million A-scans and 4.5 GVoxels per second.

Authors:  Wolfgang Wieser; Benjamin R Biedermann; Thomas Klein; Christoph M Eigenwillig; Robert Huber
Journal:  Opt Express       Date:  2010-07-05       Impact factor: 3.894

3.  Performance of serial time-encoded amplified microscope.

Authors:  Kevin K Tsia; Keisuke Goda; Dale Capewell; Bahram Jalali
Journal:  Opt Express       Date:  2010-05-10       Impact factor: 3.894

4.  Spectrally encoded confocal microscopy.

Authors:  G J Tearney; R H Webb; B E Bouma
Journal:  Opt Lett       Date:  1998-08-01       Impact factor: 3.776

5.  Performance of fourier domain vs. time domain optical coherence tomography.

Authors:  R Leitgeb; C Hitzenberger; Adolf Fercher
Journal:  Opt Express       Date:  2003-04-21       Impact factor: 3.894

6.  Breathing laser as an inertia-free swept source for high-quality ultrafast optical bioimaging.

Authors:  Xiaoming Wei; Jingjiang Xu; Yiqing Xu; Luoqin Yu; Jianbing Xu; Bowen Li; Andy K S Lau; Xie Wang; Chi Zhang; Kevin K Tsia; Kenneth K Y Wong
Journal:  Opt Lett       Date:  2014-12-01       Impact factor: 3.776

7.  Performance of megahertz amplified optical time-stretch optical coherence tomography (AOT-OCT).

Authors:  Jingjiang Xu; Xiaoming Wei; Luoqin Yu; Chi Zhang; Jianbing Xu; K K Y Wong; Kevin K Tsia
Journal:  Opt Express       Date:  2014-09-22       Impact factor: 3.894

8.  High-throughput optical coherence tomography at 800 nm.

Authors:  Keisuke Goda; Ali Fard; Omer Malik; Gilbert Fu; Alan Quach; Bahram Jalali
Journal:  Opt Express       Date:  2012-08-27       Impact factor: 3.894

9.  Akinetic all-semiconductor programmable swept-source at 1550 nm and 1310 nm with centimeters coherence length.

Authors:  M Bonesi; M P Minneman; J Ensher; B Zabihian; H Sattmann; P Boschert; E Hoover; R A Leitgeb; M Crawford; W Drexler
Journal:  Opt Express       Date:  2014-02-10       Impact factor: 3.894

10.  Coherent anti-Stokes Raman scattering hyperspectral tissue imaging with a wavelength-swept system.

Authors:  Steve Bégin; Bryan Burgoyne; Vincent Mercier; Alain Villeneuve; Réal Vallée; Daniel Côté
Journal:  Biomed Opt Express       Date:  2011-04-22       Impact factor: 3.732

View more
  8 in total

1.  Assessing the effects of riboflavin/UV-A crosslinking on porcine corneal mechanical anisotropy with optical coherence elastography.

Authors:  Manmohan Singh; Jiasong Li; Zhaolong Han; Raksha Raghunathan; Achuth Nair; Chen Wu; Chih-Hao Liu; Salavat Aglyamov; Michael D Twa; Kirill V Larin
Journal:  Biomed Opt Express       Date:  2016-12-19       Impact factor: 3.732

2.  Compressed sensing-enabled phase-sensitive swept-source optical coherence tomography.

Authors:  Yuye Ling; William Meiniel; Rajinder Singh-Moon; Elsa Angelini; Jean-Christophe Olivo-Marin; Christine P Hendon
Journal:  Opt Express       Date:  2019-01-21       Impact factor: 3.894

3.  All-passive pixel super-resolution of time-stretch imaging.

Authors:  Antony C S Chan; Ho-Cheung Ng; Sharat C V Bogaraju; Hayden K H So; Edmund Y Lam; Kevin K Tsia
Journal:  Sci Rep       Date:  2017-03-17       Impact factor: 4.379

4.  Deep Cytometry: Deep learning with Real-time Inference in Cell Sorting and Flow Cytometry.

Authors:  Yueqin Li; Ata Mahjoubfar; Claire Lifan Chen; Kayvan Reza Niazi; Li Pei; Bahram Jalali
Journal:  Sci Rep       Date:  2019-07-31       Impact factor: 4.379

5.  1.1-µm Band Extended Wide-Bandwidth Wavelength-Swept Laser Based on Polygonal Scanning Wavelength Filter.

Authors:  Gi Hyen Lee; Soyeon Ahn; Jinhwa Gene; Min Yong Jeon
Journal:  Sensors (Basel)       Date:  2021-04-27       Impact factor: 3.576

6.  Deep Learning in Label-free Cell Classification.

Authors:  Claire Lifan Chen; Ata Mahjoubfar; Li-Chia Tai; Ian K Blaby; Allen Huang; Kayvan Reza Niazi; Bahram Jalali
Journal:  Sci Rep       Date:  2016-03-15       Impact factor: 4.379

7.  Ultrafast laser-scanning time-stretch imaging at visible wavelengths.

Authors:  Jiang-Lai Wu; Yi-Qing Xu; Jing-Jiang Xu; Xiao-Ming Wei; Antony Cs Chan; Anson Hl Tang; Andy Ks Lau; Bob Mf Chung; Ho Cheung Shum; Edmund Y Lam; Kenneth Ky Wong; Kevin K Tsia
Journal:  Light Sci Appl       Date:  2017-01-27       Impact factor: 17.782

8.  Neural network-based image reconstruction in swept-source optical coherence tomography using undersampled spectral data.

Authors:  Yijie Zhang; Tairan Liu; Manmohan Singh; Ege Çetintaş; Yilin Luo; Yair Rivenson; Kirill V Larin; Aydogan Ozcan
Journal:  Light Sci Appl       Date:  2021-07-29       Impact factor: 17.782

  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.