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Literature DB >> 26503895

Emerging Treatments for Retinitis Pigmentosa: Genes and stem cells, as well as new electronic and medical therapies, are gaining ground.

Michael K Lin¹, Yi-Ting Tsai¹, Stephen H Tsang¹.

Abstract

Entities: Chemical Disease Gene Mutation Species

Year: 2015 PMID： 26503895 PMCID： PMC4617761

Source DB: PubMed Journal: Retin Physician ISSN： 1552-812X

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34 in total

1. A technique for retinal pigment epithelium transplantation for age-related macular degeneration secondary to extensive subfoveal scarring.

Authors: G A Peyman; K J Blinder; C L Paris; W Alturki; N C Nelson; U Desai
Journal: Ophthalmic Surg Date: 1991-02

2. RPE65 is the isomerohydrolase in the retinoid visual cycle.

Authors: Gennadiy Moiseyev; Ying Chen; Yusuke Takahashi; Bill X Wu; Jian-Xing Ma
Journal: Proc Natl Acad Sci U S A Date: 2005-08-22 Impact factor: 11.205

3. The Detection of Motion by Blind Subjects With the Epiretinal 60-Electrode (Argus II) Retinal Prosthesis.

Authors: Jessy D Dorn; Ashish K Ahuja; Avi Caspi; Lyndon da Cruz; Gislin Dagnelie; Jose-Alain Sahel; Robert J Greenberg; Matthew J McMahon
Journal: JAMA Ophthalmol Date: 2013-02 Impact factor: 7.389

4. Long-term safety and efficacy of human-induced pluripotent stem cell (iPS) grafts in a preclinical model of retinitis pigmentosa.

Authors: Yao Li; Yi-Ting Tsai; Chun-Wei Hsu; Deniz Erol; Jin Yang; Wen-Hsuan Wu; Richard J Davis; Dieter Egli; Stephen H Tsang
Journal: Mol Med Date: 2012-12-06 Impact factor: 6.354

5. Identification and characterization of rod-derived cone viability factor.

Authors: Thierry Léveillard; Saddek Mohand-Saïd; Olivier Lorentz; David Hicks; Anne-Claire Fintz; Emmanuelle Clérin; Manuel Simonutti; Valérie Forster; Nükhet Cavusoglu; Frédéric Chalmel; Pascal Dollé; Olivier Poch; George Lambrou; José-Alain Sahel
Journal: Nat Genet Date: 2004-06-27 Impact factor: 38.330

6. Gene therapy in patient-specific stem cell lines and a preclinical model of retinitis pigmentosa with membrane frizzled-related protein defects.

Authors: Yao Li; Wen-Hsuan Wu; Chun-Wei Hsu; Huy V Nguyen; Yi-Ting Tsai; Lawrence Chan; Takayuki Nagasaki; Irene H Maumenee; Lawrence A Yannuzzi; Quan V Hoang; Haiqing Hua; Dieter Egli; Stephen H Tsang
Journal: Mol Ther Date: 2014-06-04 Impact factor: 11.454

7. Transplantation of fetal retinal pigment epithelium in age-related macular degeneration with subfoveal neovascularization.

Authors: P V Algvere; L Berglin; P Gouras; Y Sheng
Journal: Graefes Arch Clin Exp Ophthalmol Date: 1994-12 Impact factor: 3.117

8. Restoration of vision after transplantation of photoreceptors.

Authors: R A Pearson; A C Barber; M Rizzi; C Hippert; T Xue; E L West; Y Duran; A J Smith; J Z Chuang; S A Azam; U F O Luhmann; A Benucci; C H Sung; J W Bainbridge; M Carandini; K-W Yau; J C Sowden; R R Ali
Journal: Nature Date: 2012-05-03 Impact factor: 49.962

9. Gene therapy for Leber's congenital amaurosis is safe and effective through 1.5 years after vector administration.

Authors: Francesca Simonelli; Albert M Maguire; Francesco Testa; Eric A Pierce; Federico Mingozzi; Jeannette L Bennicelli; Settimio Rossi; Kathleen Marshall; Sandro Banfi; Enrico M Surace; Junwei Sun; T Michael Redmond; Xiaosong Zhu; Kenneth S Shindler; Gui-Shuang Ying; Carmela Ziviello; Carmela Acerra; J Fraser Wright; Jennifer Wellman McDonnell; Katherine A High; Jean Bennett; Alberto Auricchio
Journal: Mol Ther Date: 2009-12-01 Impact factor: 11.454

10. Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial.

Authors: Robert E MacLaren; Markus Groppe; Alun R Barnard; Charles L Cottriall; Tanya Tolmachova; Len Seymour; K Reed Clark; Matthew J During; Frans P M Cremers; Graeme C M Black; Andrew J Lotery; Susan M Downes; Andrew R Webster; Miguel C Seabra
Journal: Lancet Date: 2014-01-16 Impact factor: 79.321

10 in total

Emerging Treatments for Retinitis Pigmentosa: Genes and stem cells, as well as new electronic and medical therapies, are gaining ground.

1. A technique for retinal pigment epithelium transplantation for age-related macular degeneration secondary to extensive subfoveal scarring.

2. RPE65 is the isomerohydrolase in the retinoid visual cycle.

3. The Detection of Motion by Blind Subjects With the Epiretinal 60-Electrode (Argus II) Retinal Prosthesis.

4. Long-term safety and efficacy of human-induced pluripotent stem cell (iPS) grafts in a preclinical model of retinitis pigmentosa.

5. Identification and characterization of rod-derived cone viability factor.

6. Gene therapy in patient-specific stem cell lines and a preclinical model of retinitis pigmentosa with membrane frizzled-related protein defects.

7. Transplantation of fetal retinal pigment epithelium in age-related macular degeneration with subfoveal neovascularization.

8. Restoration of vision after transplantation of photoreceptors.

9. Gene therapy for Leber's congenital amaurosis is safe and effective through 1.5 years after vector administration.

10. Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial.

Review 1. Attenuation of Inherited and Acquired Retinal Degeneration Progression with Gene-based Techniques.

2. Morphological Factors that Underlie Neural Sensitivity to Stimulation in the Retina.

3. Reprogramming towards anabolism impedes degeneration in a preclinical model of retinitis pigmentosa.

Review 4. Eclectic Ocular Comorbidities and Systemic Diseases with Eye Involvement: A Review.

Review 5. Genome Surgery and Gene Therapy in Retinal Disorders.

6. Structural modeling of a novel SLC38A8 mutation that causes foveal hypoplasia.

Review 7. Correction of Monogenic and Common Retinal Disorders with Gene Therapy.

Review 8. Translation of CRISPR Genome Surgery to the Bedside for Retinal Diseases.

Review 9. Guiding Lights in Genome Editing for Inherited Retinal Disorders: Implications for Gene and Cell Therapy.

Review 10. The utility and risks of therapeutic nanotechnology in the retina.