BACKGROUND: The authors analyzed data from Polish national POL-TAVI registry in terms of paravalvular leak (PVL) occurrence after transcatheter aortic valve implantation (TAVI) and its impact on clinical outcomes. METHODS: A total of 331 patients with severe aortic stenosis underwent TAVI (Edwards Sapien, n = 141; CoreValve, n = 190). The grade of PVL and survival rate were assessed at6-month follow-up. RESULTS: One hundred and eighty-one (54.7%) patients developed mild PVL, and 22 (6.6%) - moderate PVL after TAVI. No severe PVLs were observed. Occurrence of moderate PVL was device dependent and more frequent in the CoreValve group (p = 0.02). Larger CoreValve device used correlated with the grade of PVL (Spearman: r = 0.19; p = 0.01), but for Edwards Sapien devices this correlation was inverted (Spearman: r = -0.62; p = 0.01). Six-month mortality rate was not significant between patients with no or mild PVL compared to those with moderate PVL (p = 0.12). CONCLUSIONS: The PVL occurrence remains a frequent problem after TAVI and is device de-pendent, more common with Edwards 23 mm valve and 31 mm CoreValve prosthesis.
BACKGROUND: The authors analyzed data from Polish national POL-TAVI registry in terms of paravalvular leak (PVL) occurrence after transcatheter aortic valve implantation (TAVI) and its impact on clinical outcomes. METHODS: A total of 331 patients with severe aortic stenosis underwent TAVI (Edwards Sapien, n = 141; CoreValve, n = 190). The grade of PVL and survival rate were assessed at6-month follow-up. RESULTS: One hundred and eighty-one (54.7%) patients developed mild PVL, and 22 (6.6%) - moderate PVL after TAVI. No severe PVLs were observed. Occurrence of moderate PVL was device dependent and more frequent in the CoreValve group (p = 0.02). Larger CoreValve device used correlated with the grade of PVL (Spearman: r = 0.19; p = 0.01), but for Edwards Sapien devices this correlation was inverted (Spearman: r = -0.62; p = 0.01). Six-month mortality rate was not significant between patients with no or mild PVL compared to those with moderate PVL (p = 0.12). CONCLUSIONS: The PVL occurrence remains a frequent problem after TAVI and is device de-pendent, more common with Edwards 23 mm valve and 31 mm CoreValve prosthesis.
Authors: Agata Wiktorowicz; Adrian Wit; Krzysztof Piotr Malinowski; Artur Dziewierz; Lukasz Rzeszutko; Dariusz Dudek; Pawel Kleczynski Journal: Quant Imaging Med Surg Date: 2021-02
Authors: Joanna Zembala-John; Krzysztof Wilczek; Zdzisław Tobota; Piotr Chodór; Daniel Cieśla; Tomasz Jaźwiec; Waldemar Banasiak; Janina Stępińska; Zbigniew Kalarus; Grzegorz Opolski; Marian Zembala Journal: Kardiochir Torakochirurgia Pol Date: 2016-12-30
Authors: Łukasz Wiewiórka; Robert Sobczyński; Jarosław Trębacz; Jerzy Sadowski; Dariusz Dudek; Maciej Stąpór; Janusz Konstanty-Kalandyk; Robert Musiał; Andrzej Gackowski; Krzystof Malinowski; Paweł Kleczyński; Krzysztof Żmudka; Bogusław Kapelak; Jacek Legutko Journal: Postepy Kardiol Interwencyjnej Date: 2021-03-27 Impact factor: 1.426