| Literature DB >> 26499168 |
Hong-Lian Ai1, Man-Si Yang1, Shu-Hui Zi1, Hua-Chun Guo2.
Abstract
Three new sativene sesquiterpenoids, bipolenins A-C (1-3), together with two known analogs (4 and 5), were obtained from cultures of endophytic fungus Bipolaris eleusines. The structures of new compounds were elucidated on the basis of extensive spectroscopic analyses. Compound 2 showed weak inhibitory activities against lung cancer A-549 and breast cancer MCF-7 with IC50 values of 33.2 and 19.1 μmol, respectively.Entities:
Keywords: Bipolaris eleusines; cytotoxicity; endophytic fungus; sativene sesquiterpenoids
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Year: 2015 PMID： 26499168 DOI： 10.1080/10286020.2015.1041929
Source DB: PubMed Journal: J Asian Nat Prod Res ISSN： 1028-6020 Impact factor: 1.569