Literature DB >> 26497656

[Prehospital analgesia by paramedics in Rhineland-Palatinate : Feasability, analgesic effectiveness and safety of intravenous paracetamol].

T Luiz1,2, G Scherer3, A Wickenkamp4, F Blaschke5, W Hoffmann6, M Schiffer7, J Zimmer7, S Schaefer8, C Voigt8.   

Abstract

BACKGROUND: In contrast to the widespread practice in life-threatening emergencies, delegation of medical pain therapy to paramedics by the medical director  of Emergency Medical Services, EMS, are still the exception in Germany. This is due to the fact that in non-life-threatening situations, the expected benefit and potential side effects of drug therapy have to be carefully weighed. In addition, in Germany federal law generally restricts the administration of opiates to physicians.
METHODS: In 2011 the medical directors of EMS in the German state of Rhineland- Palatinate (4 million inhabitants) developed and implemented a standard operating procedure (SOP) for paramedics related to the prehospital parenteral administration of paracetamol for patients with isolated limb trauma. After a 2 h training session and examination, paramedics were authorized to administer 1 g of paracetamol to patients with a pain score > 5 points on an 11-point numerical rating scale (NRS). For purposes of quality management, every administration of paracetamol had to be prospectively documented on a specific electronic mission form.
RESULTS: A total of 416 mission forms could be analyzed. After administration of paracetamol the median NRS score decreased from 8 points (interquartile range: 6; 8) to 4 points (interquartile range: 3; 7). In 51.2 % of the patients the pain intensity was reduced by at least 3 NRS points and in 50.5 % of the patients the NRS was less than 5 points after treatment. The extent of pain reduction was positively correlated with the initial NRS value (r = 0.31, p < 0.0001). No serious side effects were noted. The percentage of patients with an initial heart rate > 100/min declined from 14.6 % to 5.2 % after the administration of paracetamol (p < 0.0001), 18.7 % of the patients received paracetamol for trauma not related to the extremities and 7 % of the patients for nontraumatic pain. An emergency physician was involved in 50 % of the EMS missions and 98.6 % of the patients were transported to a hospital for further diagnostics and treatment.
CONCLUSION: The prehospital intravenous administration of paracetamol by paramedics to patients with limb trauma is simple, safe and in 50 % of the patients effective in achieving a NRS value < 5; however, further improvements in prehospital pain therapy initiated by paramedics are desirable, especially in patients with an initial NRS value > 7.

Entities:  

Keywords:  Emergency medical services; Paracetamol; Preclinical analgesia; Standard operating procedures; Trauma

Year:  2015        PMID: 26497656     DOI: 10.1007/s00101-015-0089-4

Source DB:  PubMed          Journal:  Anaesthesist        ISSN: 0003-2417            Impact factor:   1.041


  21 in total

1.  Randomised comparison of intravenous paracetamol and intravenous morphine for acute traumatic limb pain in the emergency department.

Authors:  Michelle Craig; Richard Jeavons; Joanne Probert; Jonathan Benger
Journal:  Emerg Med J       Date:  2011-03-01       Impact factor: 2.740

Review 2.  A literature review of randomized clinical trials of intravenous acetaminophen (paracetamol) for acute postoperative pain.

Authors:  Alex Macario; Mike A Royal
Journal:  Pain Pract       Date:  2010-11-28       Impact factor: 3.183

Review 3.  Single-dose intravenous paracetamol or propacetamol for prevention or treatment of postoperative pain: a systematic review and meta-analysis.

Authors:  E D McNicol; A Tzortzopoulou; M S Cepeda; M B D Francia; T Farhat; R Schumann
Journal:  Br J Anaesth       Date:  2011-05-09       Impact factor: 9.166

Review 4.  Single dose intravenous propacetamol or intravenous paracetamol for postoperative pain.

Authors:  Aikaterini Tzortzopoulou; Ewan D McNicol; M Soledad Cepeda; Marie Belle D Francia; Tamman Farhat; Roman Schumann
Journal:  Cochrane Database Syst Rev       Date:  2011-10-05

5.  What decline in pain intensity is meaningful to patients with acute pain?

Authors:  M Soledad Cepeda; Juan M Africano; Rodolfo Polo; Ramiro Alcala; Daniel B Carr
Journal:  Pain       Date:  2003-09       Impact factor: 6.961

Review 6.  [Guideline 'Pain management for trauma patients in the chain of emergency care'].

Authors:  Sivera A A Berben; Hennie H L M Kemps; Pierre M van Grunsven; Joke A J Mintjes-de Groot; Robert T M van Dongen; Lisette Schoonhoven
Journal:  Ned Tijdschr Geneeskd       Date:  2011

7.  The impact of patient sex on paramedic pain management in the prehospital setting.

Authors:  Bill Lord; James Cui; Anne-Maree Kelly
Journal:  Am J Emerg Med       Date:  2009-06       Impact factor: 2.469

8.  Paracetamol versus metamizol in the treatment of postoperative pain after breast surgery: a randomized, controlled trial.

Authors:  Henning Ohnesorge; Berhold Bein; Robert Hanss; Helga Francksen; Laura Mayer; Jens Scholz; Peter H Tonner
Journal:  Eur J Anaesthesiol       Date:  2009-08       Impact factor: 4.330

9.  Comparison of ketamine-low-dose midozolam with midazolam-fentanyl for orthopedic emergencies: a double-blind randomized trial.

Authors:  Erdem Cevik; Serkan Bilgic; Erden Kilic; Orhan Cinar; Hakan Hasman; Ayhan Yahya Acar; Murat Eroglu
Journal:  Am J Emerg Med       Date:  2012-08-31       Impact factor: 2.469

10.  An Evidence-based Guideline for prehospital analgesia in trauma.

Authors:  Marianne Gausche-Hill; Kathleen M Brown; Zoë J Oliver; Comilla Sasson; Peter S Dayan; Nicholas M Eschmann; Tasmeen S Weik; Benjamin J Lawner; Ritu Sahni; Yngve Falck-Ytter; Joseph L Wright; Knox Todd; Eddy S Lang
Journal:  Prehosp Emerg Care       Date:  2013-11-26       Impact factor: 3.077

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  6 in total

1.  [Analgesia for trauma patients in emergency medicine].

Authors:  D Häske; B W Böttiger; B Bouillon; M Fischer; Gernot Gaier; B Gliwitzky; M Helm; P Hilbert-Carius; B Hossfeld; B Schempf; A Wafaisade; M Bernhard
Journal:  Anaesthesist       Date:  2020-02       Impact factor: 1.041

Review 2.  Analgesia in Patients with Trauma in Emergency Medicine.

Authors:  David Häske; Bernd W Böttiger; Bertil Bouillon; Matthias Fischer; Gernot Gaier; Bernhard Gliwitzky; Matthias Helm; Peter Hilbert-Carius; Björn Hossfeld; Christoph Meisner; Benjamin Schempf; Arasch Wafaisade; Michael Bernhard
Journal:  Dtsch Arztebl Int       Date:  2017-11-17       Impact factor: 5.594

3.  [Prehospital analgesia by emergency physicians and paramedics : Comparison of effectiveness].

Authors:  B Schempf; S Casu; D Häske
Journal:  Anaesthesist       Date:  2017-03-03       Impact factor: 1.041

4.  Acute pain in the prehospital setting: a register-based study of 41.241 patients.

Authors:  Kristian D Friesgaard; Ingunn S Riddervold; Hans Kirkegaard; Erika F Christensen; Lone Nikolajsen
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2018-07-03       Impact factor: 2.953

5.  Usability and effectiveness of inhaled methoxyflurane for prehospital analgesia - a prospective, observational study.

Authors:  Helmut Trimmel; Alexander Egger; Reinhard Doppler; Mathias Pimiskern; Wolfgang G Voelckel
Journal:  BMC Emerg Med       Date:  2022-01-15

Review 6.  [Volatile anesthetics for prehospital analgesia by paramedics-An overview].

Authors:  Helmut Trimmel; Alexander Egger; Reinhard Doppler; Christoph Beywinkler; Wolfgang G Voelckel; Janett Kreutziger
Journal:  Anaesthesist       Date:  2021-10-18       Impact factor: 1.041

  6 in total

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