Literature DB >> 26495437

The Role of Macrophage in the Pathogenesis of Brain Arteriovenous Malformation.

Li Ma1, Yi Guo2, Yuan-Li Zhao3, Hua Su4.   

Abstract

Brain arteriovenous malformation (BAVM) is an important risk factor for intracranial hemorrhage, especially in children and young adults. Inflammation has been implicated in BAVM lesion progression. Among various inflammatory components, macrophage is one of the major inflammatory cells present in human ruptured and unruptured BAVM and in the BAVM lesions of animal models. The role of macrophage in BAVM pathogenesis is not fully understood. In this review, we summarize recent studies on macrophages and introduce a non-invasive imaging protocol as a potential tool for detecting macrophage in BAVM and predicting the risk of BAVM rupture.

Entities:  

Keywords:  Brain arteriovenous malformation; Inflammation; Macrophage; Pathogenesis

Year:  2015        PMID: 26495437      PMCID: PMC4610371          DOI: 10.17554/j.issn.2409-3548.2015.01.12

Source DB:  PubMed          Journal:  Int J Hematol Res        ISSN: 2409-3548


  47 in total

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2.  Silent intralesional microhemorrhage as a risk factor for brain arteriovenous malformation rupture.

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Journal:  Stroke       Date:  2012-02-02       Impact factor: 7.914

3.  MRI using ferumoxytol improves the visualization of central nervous system vascular malformations.

Authors:  Edit Dósa; Suchita Tuladhar; Leslie L Muldoon; Bronwyn E Hamilton; William D Rooney; Edward A Neuwelt
Journal:  Stroke       Date:  2011-04-14       Impact factor: 7.914

4.  Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation.

Authors:  T N Sato; Y Tozawa; U Deutsch; K Wolburg-Buchholz; Y Fujiwara; M Gendron-Maguire; T Gridley; H Wolburg; W Risau; Y Qin
Journal:  Nature       Date:  1995-07-06       Impact factor: 49.962

5.  Macrophage migration inhibitory factor reduces apoptosis in cerebral arteriovenous malformations.

Authors:  Guangzhong Chen; Meng Zheng; Hang Shu; Shengquan Zhan; Hongqin Wang; Dong Zhou; Shaojian Zeng; Kai Tang; Lei Feng
Journal:  Neurosci Lett       Date:  2011-12-22       Impact factor: 3.046

6.  Ferumoxytol-enhanced MRI to Image Inflammation within Human Brain Arteriovenous Malformations: A Pilot Investigation.

Authors:  David M Hasan; Matthew Amans; Tarik Tihan; Christopher Hess; Yi Guo; Soonmee Cha; Hua Su; Alastair J Martin; Michael T Lawton; Edward A Neuwelt; David A Saloner; William L Young
Journal:  Transl Stroke Res       Date:  2012-07       Impact factor: 6.829

Review 7.  Brain arteriovenous malformation modeling, pathogenesis, and novel therapeutic targets.

Authors:  Wanqiu Chen; Eun-Jung Choi; Cameron M McDougall; Hua Su
Journal:  Transl Stroke Res       Date:  2014-04-12       Impact factor: 6.829

8.  Frequency of intracranial hemorrhage as a presenting symptom and subtype analysis: a population-based study of intracranial vascular malformations in Olmsted Country, Minnesota.

Authors:  R D Brown; D O Wiebers; J C Torner; W M O'Fallon
Journal:  J Neurosurg       Date:  1996-07       Impact factor: 5.115

9.  Gene microarray analysis of human brain arteriovenous malformations.

Authors:  Tomoki Hashimoto; Michael T Lawton; Gen Wen; Guo-Yuan Yang; Thomas Chaly; Campbell L Stewart; Holly K Dressman; Nicholas M Barbaro; Douglas A Marchuk; William L Young
Journal:  Neurosurgery       Date:  2004-02       Impact factor: 4.654

10.  Evidence that acetylsalicylic acid attenuates inflammation in the walls of human cerebral aneurysms: preliminary results.

Authors:  David M Hasan; Nohra Chalouhi; Pascal Jabbour; Aaron S Dumont; David K Kung; Vincent A Magnotta; William L Young; Tomoki Hashimoto; H Richard Winn; Donald Heistad
Journal:  J Am Heart Assoc       Date:  2013-02-22       Impact factor: 5.501

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Authors:  Rui Zhang; Zhenying Han; Vincent Degos; Fanxia Shen; Eun-Jung Choi; Zhengda Sun; Shuai Kang; Michael Wong; Wan Zhu; Lei Zhan; Helen M Arthur; S Paul Oh; Marie E Faughnan; Hua Su
Journal:  Angiogenesis       Date:  2016-06-20       Impact factor: 9.596

2.  De novo brain arteriovenous malformation formation and development: A case report.

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Journal:  World J Clin Cases       Date:  2022-06-26       Impact factor: 1.534

Review 3.  Recent Advances in Basic Research for Brain Arteriovenous Malformation.

Authors:  Leandro Barbosa Do Prado; Chul Han; S Paul Oh; Hua Su
Journal:  Int J Mol Sci       Date:  2019-10-25       Impact factor: 5.923

Review 4.  Recent progress understanding pathophysiology and genesis of brain AVM-a narrative review.

Authors:  Hans-Jakob Steiger
Journal:  Neurosurg Rev       Date:  2021-04-10       Impact factor: 3.042

  4 in total

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