| Literature DB >> 26495437 |
Li Ma1, Yi Guo2, Yuan-Li Zhao3, Hua Su4.
Abstract
Brain arteriovenous malformation (BAVM) is an important risk factor for intracranial hemorrhage, especially in children and young adults. Inflammation has been implicated in BAVM lesion progression. Among various inflammatory components, macrophage is one of the major inflammatory cells present in human ruptured and unruptured BAVM and in the BAVM lesions of animal models. The role of macrophage in BAVM pathogenesis is not fully understood. In this review, we summarize recent studies on macrophages and introduce a non-invasive imaging protocol as a potential tool for detecting macrophage in BAVM and predicting the risk of BAVM rupture.Entities:
Keywords: Brain arteriovenous malformation; Inflammation; Macrophage; Pathogenesis
Year: 2015 PMID: 26495437 PMCID: PMC4610371 DOI: 10.17554/j.issn.2409-3548.2015.01.12
Source DB: PubMed Journal: Int J Hematol Res ISSN: 2409-3548