Marisa Santos1, Monica A C T Cintra1, Andrea L Monteiro1, Braulio Santos1, Fernando Gusmão-Filho2, Mônica Viegas Andrade3, Kenya Noronha3, Luciane N Cruz4, Suzi Camey5, Bernardo Tura1, Paul Kind6. 1. Instituto Nacional de Cardiologia, Rio de Janeiro, Brazil (MS, MACTC, ALM, BS, BT) 2. Instituto de Medicina Integral Professor Fernando Figueira, Recife, Brazil (FG-f) 3. Departamento de Economia, Centro de Desenvolvimento e Planejamento Regional, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil (MVA, KN) 4. Departamento de Epidemiologia, Programa de Pós-graduação em Epidemiologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil (LNC) 5. Departamento de Estatística, Programa de Pós-graduação em Epidemiologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil (SC) 6. Academic Unit of Health Economics, Institute of Health Sciences, University of Leeds, Leeds, UK (PK)
Abstract
BACKGROUND: Most EQ-5D-3L valuation studies include the same sample of health states that was used in the protocol of the original UK Measurement and Valuation of Health (MVH) study. Thus far, no studies using a time tradeoff utility elicitation method have been carried out using all 243 EQ-5D health states. Because the values and preferences regarding health outcomes differ among countries, it is essential to have country-specific data to enable local high-level decisions regarding resource allocation. This study developed a country-specific set of values for EQ-5D-3L health states. METHODS: A multicentric study was conducted in 4 Brazilian areas. A probabilistic sample of the general population, aged 18 to 64 y, stratified by age and gender, was surveyed. The interview followed a revised version of the MVH protocol, in which all 243 health states were valued. Each respondent ranked and valued 7 health states using the TTO in a home interview. RESULTS: Data were collected from 9148 subjects. The best-fitting regression model was an individual-level mixed-effects model without any interaction terms. The dimensions "Mobility" and "Usual Activities" were associated with higher losses in health state utility value. The "Anxiety/Depression" dimension was the domain that contributed to lower losses in health state utility value. CONCLUSIONS: This study generated significant insight into the Brazilian population's health preferences that can be applied to health technology assessment and economic analyses in Brazil. This information represents an important new tool that can be used in Brazilian health policy creation and evaluation.
BACKGROUND: Most EQ-5D-3L valuation studies include the same sample of health states that was used in the protocol of the original UK Measurement and Valuation of Health (MVH) study. Thus far, no studies using a time tradeoff utility elicitation method have been carried out using all 243 EQ-5D health states. Because the values and preferences regarding health outcomes differ among countries, it is essential to have country-specific data to enable local high-level decisions regarding resource allocation. This study developed a country-specific set of values for EQ-5D-3L health states. METHODS: A multicentric study was conducted in 4 Brazilian areas. A probabilistic sample of the general population, aged 18 to 64 y, stratified by age and gender, was surveyed. The interview followed a revised version of the MVH protocol, in which all 243 health states were valued. Each respondent ranked and valued 7 health states using the TTO in a home interview. RESULTS: Data were collected from 9148 subjects. The best-fitting regression model was an individual-level mixed-effects model without any interaction terms. The dimensions "Mobility" and "Usual Activities" were associated with higher losses in health state utility value. The "Anxiety/Depression" dimension was the domain that contributed to lower losses in health state utility value. CONCLUSIONS: This study generated significant insight into the Brazilian population's health preferences that can be applied to health technology assessment and economic analyses in Brazil. This information represents an important new tool that can be used in Brazilian health policy creation and evaluation.
Authors: Paulo H R F Almeida; Brian Godman; Vania Dos Santos Nunes-Nogueira; Lívia L P de Lemos; Francisco de Assis Acúrcio; Augusto A Guerra-Junior; Vânia E de Araújo; Alessandra M Almeida; Juliana Alvares-Teodoro Journal: Clin Diabetes Date: 2022
Authors: Regis Goulart Rosa; Julia Spinardi; Kristen E Allen; Josélia Manfio; Cintia Laura Pereira de Araujo; Mírian Cohen; Caroline Cabral Robinson; Daniel Sganzerla; Diogo Ferreira; Emanuel Maltempi de Souza; Jaqueline Carvalho de Oliveira; Daniela Fiori Gradia; Ana Paula Carneiro Brandalize; Gabriela Almeida Kucharski; Fernando Pedrotti; Cristina de Oliveira Rodrigues; Moe H Kyaw; Graciela Del Carmen Morales Castillo; Amit Srivastava; John M McLaughlin; Maicon Falavigna Journal: PLoS One Date: 2022-10-20 Impact factor: 3.752
Authors: Jéssica Barreto Ribeiro Dos Santos; Alessandra Maciel Almeida; Francisco de Assis Acurcio; Haliton Alves de Oliveira Junior; Adriana Maria Kakehasi; Augusto Afonso Guerra Junior; Marion Bennie; Brian Godman; Juliana Alvares Journal: J Comp Eff Res Date: 2016-09-19 Impact factor: 1.744
Authors: Bruna de Oliveira Ascef; João Paulo Amaral Haddad; Juliana Álvares; Augusto Afonso Guerra; Ediná Alves Costa; Francisco de Assis Acurcio; Ione Aquemi Guibu; Karen Sarmento Costa; Margô Gomes de Oliveira Karnikowski; Orlando Mario Soeiro; Silvana Nair Leite; Micheline Rosa Silveira Journal: Rev Saude Publica Date: 2017-11-13 Impact factor: 2.106
Authors: Luciana Bahia; Rosane Kupfer; Denise Momesso; Debora A P Cabral; Balduino Tschiedel; Marcia Puñales; Suzana Lavigne; Cristina F S Façanha; Adriana C Forti; Angela D N Mendes; Bernardo R Tura Journal: Diabetol Metab Syndr Date: 2017-01-28 Impact factor: 3.320
Authors: Paula M Luz; Benjamin Osher; Beatriz Grinsztejn; Rachel L Maclean; Elena Losina; Madeline E Stern; Claudio J Struchiner; Robert A Parker; Kenneth A Freedberg; Fabio Mesquita; Rochelle P Walensky; Valdilea G Veloso; A David Paltiel Journal: J Int AIDS Soc Date: 2018-03 Impact factor: 5.396