Literature DB >> 26488809

Gut-Busters: IL-17 Ain't Afraid of No IL-23.

Natasha Whibley1, Sarah L Gaffen2.   

Abstract

Interleukin-23 (IL-23) is considered a critical regulator of IL-17 in lymphocytes. Whereas antibodies targeting IL-23 ameliorate colitis, IL-17 neutralization exacerbates disease. In this issue, Cua and colleagues and Maxwell and colleagues show that IL-17 maintains intestinal barrier integrity, helping explain this dichotomy (Lee et al., 2015; Maxwell et al., 2015).
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2015        PMID： 26488809      PMCID： PMC4804829          DOI： 10.1016/j.immuni.2015.10.001

Source DB:  PubMed          Journal:  Immunity        ISSN： 1074-7613            Impact factor:   31.745


  11 in total

1.  Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial.

Authors:  Wolfgang Hueber; Bruce E Sands; Steve Lewitzky; Marc Vandemeulebroecke; Walter Reinisch; Peter D R Higgins; Jan Wehkamp; Brian G Feagan; Michael D Yao; Marek Karczewski; Jacek Karczewski; Nicole Pezous; Stephan Bek; Gerard Bruin; Bjoern Mellgard; Claudia Berger; Marco Londei; Arthur P Bertolino; Gervais Tougas; Simon P L Travis
Journal:  Gut       Date:  2012-05-17       Impact factor: 23.059

Review 2.  Secukinumab: first global approval.

Authors:  Mark Sanford; Kate McKeage
Journal:  Drugs       Date:  2015-02       Impact factor: 9.546

3.  Differential Roles for Interleukin-23 and Interleukin-17 in Intestinal Immunoregulation.

Authors:  Joseph R Maxwell; Yu Zhang; William A Brown; Carole L Smith; Fergus R Byrne; Mike Fiorino; Erin Stevens; Jeannette Bigler; John A Davis; James B Rottman; Alison L Budelsky; Antony Symons; Jennifer E Towne
Journal:  Immunity       Date:  2015-09-29       Impact factor: 31.745

4.  Interleukin-23-Independent IL-17 Production Regulates Intestinal Epithelial Permeability.

Authors:  Jacob S Lee; Cristina M Tato; Barbara Joyce-Shaikh; Muhammet F Gulen; Fatih Gulan; Corinne Cayatte; Yi Chen; Wendy M Blumenschein; Michael Judo; Gulesi Ayanoglu; Terrill K McClanahan; Xiaoxia Li; Daniel J Cua
Journal:  Immunity       Date:  2015-09-29       Impact factor: 31.745

5.  Cutting edge: regulation of intestinal inflammation and barrier function by IL-17C.

Authors:  Joseph M Reynolds; Gustavo J Martinez; Kalyan C Nallaparaju; Seon Hee Chang; Yi-Hong Wang; Chen Dong
Journal:  J Immunol       Date:  2012-09-28       Impact factor: 5.422

6.  IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6.

Authors:  David Yen; Jeanne Cheung; Heleen Scheerens; Frédérique Poulet; Terrill McClanahan; Brent McKenzie; Melanie A Kleinschek; Alex Owyang; Jeanine Mattson; Wendy Blumenschein; Erin Murphy; Manjiri Sathe; Daniel J Cua; Robert A Kastelein; Donna Rennick
Journal:  J Clin Invest       Date:  2006-05       Impact factor: 14.808

7.  TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology.

Authors:  Mandy J McGeachy; Kristian S Bak-Jensen; Yi Chen; Cristina M Tato; Wendy Blumenschein; Terrill McClanahan; Daniel J Cua
Journal:  Nat Immunol       Date:  2007-11-11       Impact factor: 25.606

8.  A protective function for interleukin 17A in T cell-mediated intestinal inflammation.

Authors:  William O'Connor; Masahito Kamanaka; Carmen J Booth; Terrence Town; Susumu Nakae; Yoichiro Iwakura; Jay K Kolls; Richard A Flavell
Journal:  Nat Immunol       Date:  2009-06       Impact factor: 25.606

9.  Growth Factor FGF2 Cooperates with Interleukin-17 to Repair Intestinal Epithelial Damage.

Authors:  Xinyang Song; Dai Dai; Xiao He; Shu Zhu; Yikun Yao; Hanchao Gao; Jingjing Wang; Fangfang Qu; Ju Qiu; Honglin Wang; Xiaoxia Li; Nan Shen; Youcun Qian
Journal:  Immunity       Date:  2015-08-25       Impact factor: 31.745

10.  Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice.

Authors:  Atsuhiro Ogawa; Akira Andoh; Yoshio Araki; Tadao Bamba; Yoshihide Fujiyama
Journal:  Clin Immunol       Date:  2004-01       Impact factor: 3.969
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  20 in total

1.  IL-17 Receptor Signaling in Oral Epithelial Cells Is Critical for Protection against Oropharyngeal Candidiasis.

Authors:  Heather R Conti; Vincent M Bruno; Erin E Childs; Sean Daugherty; Joseph P Hunter; Bemnet G Mengesha; Danielle L Saevig; Matthew R Hendricks; Bianca M Coleman; Lucas Brane; Norma Solis; J Agustin Cruz; Akash H Verma; Abhishek V Garg; Amy G Hise; Jonathan P Richardson; Julian R Naglik; Scott G Filler; Jay K Kolls; Satrajit Sinha; Sarah L Gaffen
Journal:  Cell Host Microbe       Date:  2016-10-27       Impact factor: 21.023

2.  Fasting-Mimicking Diet Modulates Microbiota and Promotes Intestinal Regeneration to Reduce Inflammatory Bowel Disease Pathology.

Authors:  Priya Rangan; Inyoung Choi; Min Wei; Gerardo Navarrete; Esra Guen; Sebastian Brandhorst; Nobel Enyati; Gab Pasia; Daral Maesincee; Vanessa Ocon; Maya Abdulridha; Valter D Longo
Journal:  Cell Rep       Date:  2019-03-05       Impact factor: 9.423

3.  Oral epithelial IL-22/STAT3 signaling licenses IL-17-mediated immunity to oral mucosal candidiasis.

Authors:  Felix E Y Aggor; Timothy J Break; Giraldina Trevejo-Nuñez; Natasha Whibley; Bianca M Coleman; Rachel D Bailey; Daniel H Kaplan; Julian R Naglik; Wei Shan; Amol C Shetty; Carrie McCracken; Scott K Durum; Partha S Biswas; Vincent M Bruno; Jay K Kolls; Michail S Lionakis; Sarah L Gaffen
Journal:  Sci Immunol       Date:  2020-06-05

4.  A murine model of pediatric inflammatory bowel disease causes microbiota-gut-brain axis deficits in adulthood.

Authors:  Eloisa Salvo; Patricia Stokes; Ciara E Keogh; Ingrid Brust-Mascher; Carly Hennessey; Trina A Knotts; Jessica A Sladek; Kavi M Rude; Michelle Swedek; Gonzalo Rabasa; Mélanie G Gareau
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2020-07-29       Impact factor: 4.052

Review 5.  Regulation of RORγt in Inflammatory Lymphoid Cell Differentiation.

Authors:  Wendy Huang; Dan R Littman
Journal:  Cold Spring Harb Symp Quant Biol       Date:  2016-03-11

Review 6.  IL-17 Signaling: The Yin and the Yang.

Authors:  Nilesh Amatya; Abhishek V Garg; Sarah L Gaffen
Journal:  Trends Immunol       Date:  2017-02-20       Impact factor: 16.687

Review 7.  The IL-17 Family of Cytokines in Health and Disease.

Authors:  Mandy J McGeachy; Daniel J Cua; Sarah L Gaffen
Journal:  Immunity       Date:  2019-04-16       Impact factor: 31.745

8.  Fungus Among Us: The Frenemies Within.

Authors:  Felix E Y Aggor; Sing Sing Way; Sarah L Gaffen
Journal:  Trends Immunol       Date:  2019-04-30       Impact factor: 16.687

Review 9.  Mechanism-Based Treatment Strategies for IBD: Cytokines, Cell Adhesion Molecules, JAK Inhibitors, Gut Flora, and More.

Authors:  Philipp Schreiner; Markus F Neurath; Siew C Ng; Emad M El-Omar; Ala I Sharara; Taku Kobayashi; Tadakazu Hisamatsu; Toshifumi Hibi; Gerhard Rogler
Journal:  Inflamm Intest Dis       Date:  2019-07-09

10.  Tissue Damage in Radiation-Induced Oral Mucositis Is Mitigated by IL-17 Receptor Signaling.

Authors:  Jessica Saul-McBeth; John Dillon; Aaron Lee; Dylan Launder; Jacqueline M Kratch; Eanas Abutaha; Alexandria A Williamson; Allen G Schroering; Grace Michalski; Priosmita Biswas; Samuel R Conti; Amol C Shetty; Carrie McCracken; Vincent M Bruno; E Ishmael Parsai; Heather R Conti
Journal:  Front Immunol       Date:  2021-06-17       Impact factor: 7.561
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