Literature DB >> 26488029

Acute dapsone poisoning in a 3-year-old child: Case report with review of literature.

Menon Narayanankutty Sunilkumar1, Thekkuttuparambil Ananthanarayanan Ajith1, Vadakut Krishnan Parvathy1.   

Abstract

Dapsone (DDS-diamino diphenyl sulphone) is a sulfone antibiotic being used for a variety of clinical conditions. Poisoning in children by DDS is rarely reported. Poisoning in acute cases will be frequently unrecognized due to relative lack of severe signs and symptoms. Methemoglobinemia is the major life-threatening situation associated with poisoning of DDS. Hence, any delay for medical attention can lead to increased rate of mortality. In this case, we describe acute DDS poisoning in a 3-year-old child and the successful management using intravenous methylene blue.

Entities:  

Keywords:  Ascorbic acid; Dapsone; Hemolysis; Methemoglobinemia; Methylene blue

Year:  2015        PMID: 26488029      PMCID: PMC4607811          DOI: 10.12998/wjcc.v3.i10.911

Source DB:  PubMed          Journal:  World J Clin Cases        ISSN: 2307-8960            Impact factor:   1.337


  16 in total

1.  Dapsone induced methaemoglobinaemia.

Authors:  D Landers; C Bergin; A O'Leary; C Merry; S Keating; F Mulcahy
Journal:  Int J STD AIDS       Date:  1996-10       Impact factor: 1.359

Review 2.  Dapsone-induced methemoglobinemia.

Authors:  K E Ward; M W McCarthy
Journal:  Ann Pharmacother       Date:  1998-05       Impact factor: 3.154

Review 3.  Methemoglobinemia: etiology, pharmacology, and clinical management.

Authors:  R O Wright; W J Lewander; A D Woolf
Journal:  Ann Emerg Med       Date:  1999-11       Impact factor: 5.721

4.  Blockade of the action of nitric oxide in human septic shock increases systemic vascular resistance and has detrimental effects on pulmonary function after a short infusion of methylene blue.

Authors:  R Weingartner; E Oliveira; E S Oliveira; U L Sant'Anna; R P Oliveira; L A Azambuja; G Friedman
Journal:  Braz J Med Biol Res       Date:  1999-12       Impact factor: 2.590

5.  Methemoglobinemia.

Authors:  S Curry
Journal:  Ann Emerg Med       Date:  1982-04       Impact factor: 5.721

Review 6.  Dapsone-induced methemoglobinemia: a primer for clinicians.

Authors:  James A Barclay; Stamatina E Ziemba; Rami B Ibrahim
Journal:  Ann Pharmacother       Date:  2011-08-18       Impact factor: 3.154

Review 7.  Methylene blue for distributive shock: a potential new use of an old antidote.

Authors:  David H Jang; Lewis S Nelson; Robert S Hoffman
Journal:  J Med Toxicol       Date:  2013-09

8.  Dapsone-induced methemoglobinemia and hemolytic anemia.

Authors:  B L Erstad
Journal:  Clin Pharm       Date:  1992-09

9.  Methemoglobinemia related to local anesthetics: a summary of 242 episodes.

Authors:  Joanne Guay
Journal:  Anesth Analg       Date:  2009-03       Impact factor: 5.108

10.  Successful treatment of acute dapsone intoxication using charcoal hemoperfusion.

Authors:  Z H Endre; J A Charlesworth; G J Macdonald; L Woodbridge
Journal:  Aust N Z J Med       Date:  1983-10
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