Emily C Chen1,2, Nathan Papa1,2, Nathan Lawrentschuk1,2,3,4, Damien Bolton1,2,3, Shomik Sengupta1,2,3. 1. University of Melbourne, Department of Surgery, Austin Hospital, Melbourne, Australia. 2. Urology Unit, Austin Hospital, Melbourne, Australia. 3. Olivia Newton-John Cancer Research Institute, Austin Hospital, Melbourne, Australia. 4. Department of Surgical Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia.
Abstract
OBJECTIVE: To determine the incidence and assess risk factors for the development of VTE among patients undergoing major pelvic surgery for prostate and bladder cancer in an Australian tertiary referral center. PATIENTS AND METHODS: Consecutive patients undergoing major pelvic uro-oncologic surgery, namely radical cystectomy and radical prostatectomy over a five-year period (2009-2013) were identified. Patient variables and types of thromboprophylaxis (pharmacological and/or mechanical) used in this patient cohort were collected for analyses as predictive factors. RESULTS: The overall incidence of VTE was 1.8%. Patients undergoing radical cystectomy were more likely to suffer a VTE event compared to patients having radical prostatectomy. In this cohort, the risk factors for VTE include, prolonged operative time of greater than 4 hours (h), lymph node dissection (LND) and patients requiring blood transfusions. CONCLUSION: Patients undergoing major pelvic uro-oncologic surgery have an approximately 1.8% risk of developing VTE. Risk factors identified in this study should be used to guide the use of early and prolonged thromboprophylaxis.
OBJECTIVE: To determine the incidence and assess risk factors for the development of VTE among patients undergoing major pelvic surgery for prostate and bladder cancer in an Australian tertiary referral center. PATIENTS AND METHODS: Consecutive patients undergoing major pelvic uro-oncologic surgery, namely radical cystectomy and radical prostatectomy over a five-year period (2009-2013) were identified. Patient variables and types of thromboprophylaxis (pharmacological and/or mechanical) used in this patient cohort were collected for analyses as predictive factors. RESULTS: The overall incidence of VTE was 1.8%. Patients undergoing radical cystectomy were more likely to suffer a VTE event compared to patients having radical prostatectomy. In this cohort, the risk factors for VTE include, prolonged operative time of greater than 4 hours (h), lymph node dissection (LND) and patients requiring blood transfusions. CONCLUSION:Patients undergoing major pelvic uro-oncologic surgery have an approximately 1.8% risk of developing VTE. Risk factors identified in this study should be used to guide the use of early and prolonged thromboprophylaxis.
Authors: Wojciech Michalski; Grazyna Poniatowska; Joanna Jonska-Gmyrek; Jakub Kucharz; Pawel Stelmasiak; Karol Nietupski; Katarzyna Ossolinska-Skurczynska; Michal Sobieszczuk; Tomasz Demkow; Pawel Wiechno Journal: Med Oncol Date: 2019-11-25 Impact factor: 3.064
Authors: Grigoris T Gerotziafas; Ali Taher; Hikmat Abdel-Razeq; Essam AboElnazar; Alex C Spyropoulos; Salem El Shemmari; Annette K Larsen; Ismail Elalamy Journal: Oncologist Date: 2017-05-26