Literature DB >> 26481917

Management of central giant cell granuloma of the jaws with intralesional steroid injection and review of the literature.

Doğan Dolanmaz1, Alparslan Esen2, Ahmet Mihmanlı3, Kubilay Işık4.   

Abstract

PURPOSE: We report the results of the intralesional steroid injections for the management of central giant cell granuloma (CGCG) of the jaws.
METHODS: Seven CGCGs were treated with intralesional injection of corticosteroids. To accomplish this, 3.5 mL of triamcinolone and 3.5 mL of 0.5 % marcaine with 1/200,000 epinephrine (total 7 mL) were mixed. An adequate amount of steroid was injected into different areas of the lesion. This procedure was repeated on a weekly basis for 6 weeks.
RESULTS: Clinical and radiological examination showed complete resolution and ossification of the lesions in four patients. Partial recovery was achieved in two patients. One patient did not respond to the treatment and underwent surgical curettage.
CONCLUSIONS: We suggest that intralesional steroid injection is safe and effective for the treatment of CGCG, especially in non-aggressive lesions.

Entities:  

Keywords:  Corticosteroid; Giant cell granuloma; Intralesional injections; Triamcinolone acetonide

Mesh:

Substances:

Year:  2015        PMID: 26481917     DOI: 10.1007/s10006-015-0530-5

Source DB:  PubMed          Journal:  Oral Maxillofac Surg        ISSN: 1865-1550


  38 in total

1.  Giant-cell reparative granuloma, traumatic bone cyst, and fibrous (fibro-oseous) dysplasia of the jawbones.

Authors:  H L JAFFE
Journal:  Oral Surg Oral Med Oral Pathol       Date:  1953-01

2.  Intralesional injection of triamcinolone hexacetonide as an alternative treatment for central giant-cell granuloma in 21 cases.

Authors:  R L M Nogueira; R C Teixeira; R B Cavalcante; R A Ribeiro; S H B Rabenhosrt
Journal:  Int J Oral Maxillofac Surg       Date:  2010-07-31       Impact factor: 2.789

3.  Central giant cell lesions of the jaws. A clinical, radiologic, and histopathologic study.

Authors:  S B Whitaker; C A Waldron
Journal:  Oral Surg Oral Med Oral Pathol       Date:  1993-02

4.  Intralesional corticosteroid injection for treatment of central giant-cell granuloma.

Authors:  M C Adornato; K A Paticoff
Journal:  J Am Dent Assoc       Date:  2001-02       Impact factor: 3.634

Review 5.  Central giant cell lesion of mandible managed by intralesional triamcinolone injections. A report of two cases and literature review.

Authors:  Sujata Mohanty; Aakarsh Jhamb
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2009-02-01

6.  Surgical treatment and reconstruction for central giant cell granuloma of the jaws: a review of 18 cases.

Authors:  Paolo Tosco; Giulia Tanteri; Caterina Iaquinta; Massimo Fasolis; Fabio Roccia; Sid Berrone; Paolo Garzino-Demo
Journal:  J Craniomaxillofac Surg       Date:  2009-05-17       Impact factor: 2.078

7.  Intralesional corticosteroid injection for central giant cell granuloma: an alternative treatment for children.

Authors:  Flavia Prietsh Wendt; Marcos Antônio Torriani; Ana Paula Neutzling Gomes; Lenita Maria Aver de Araujo; Dione Dias Torriani
Journal:  J Dent Child (Chic)       Date:  2009 Sep-Dec

8.  Management of central giant granuloma of mandible with intralesional triamcinolone injections: a case report.

Authors:  Jason W K Choi; Richard A Kraut
Journal:  N Y State Dent J       Date:  2013-04

9.  Peripheral and central giant cell granulomas of the jaws: a demographic study.

Authors:  Mohammad Hosein Kalantar Motamedi; Nosratollah Eshghyar; Seyyed Mehdi Jafari; Essagh Lassemi; Fina Navi; Fatemeh Mashhadi Abbas; Sam Khalifeh; Pooyan Sadr Eshkevari
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod       Date:  2007-04-11

10.  Treatment of central giant cell lesions using bisphosphonates with intralesional corticosteroid injections.

Authors:  Newton Guerreiro Júnior da Silva; Aline Semblano Dias Carreira; Erick Nelo Pedreira; Fabrício Mesquita Tuji; Karem López Ortega; João de Jesus Viana Pinheiro
Journal:  Head Face Med       Date:  2012-08-22       Impact factor: 2.151

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  7 in total

1.  Central Giant Cell Granuloma Treated with Intralesional Corticosteroid Injections and Bisphosphonates: A Long-Term Follow-Up Case Study.

Authors:  Raíssa Pinheiro de Mendonça; Geovanni Pereira Mitre; Flavio Henrique Real; Maria Sueli da Silva Kataoka; Sérgio de Melo Alves Júnior; Paulo Vianna; Newton Guerreiro Da Silva Júnior; João de Jesus Viana Pinheiro
Journal:  Head Neck Pathol       Date:  2019-07-11

2.  Primary thoracic giant cell tumor of bone sensitive to steroids.

Authors:  Huiliang Yang; Gi Hye Im; Gunnlaugur Petur Nielsen; Arvin Kheterpal; Joseph H Schwab
Journal:  Skeletal Radiol       Date:  2018-03-03       Impact factor: 2.199

3.  Non-surgical treatment as an alternative for the management of central giant cell granuloma: a systematic review.

Authors:  Camila Camarini; Elen de Souza Tolentino
Journal:  Clin Oral Investig       Date:  2021-10-01       Impact factor: 3.573

4.  Management of recurrent central giant cell granuloma of mandible using intralesional corticosteroid with long-term follow-up.

Authors:  Kumar Nilesh; Anuj Dadhich; Rahul Patil
Journal:  BMJ Case Rep       Date:  2020-09-14

5.  Intra-Lesional Medicaments for the Management of Intra-Osseous Lesions of Maxilla and Mandible - Systematic Review.

Authors:  Komal Smriti; Evit John; Kalyana-Chakravarthy Pentapati; Srikanth Gadicherla; Manish Bhagania
Journal:  J Int Soc Prev Community Dent       Date:  2020-01-24

6.  Central Giant Cell Granuloma in the Mandibular Condyle in a Teenager. A Case Report with Literature Review.

Authors:  André Luís Costa Cantanhede; Sergio Olate; Adriano Freitas de Assis; Márcio de Moraes
Journal:  J Clin Med       Date:  2022-07-21       Impact factor: 4.964

7.  Peripheral and Central Giant Cell Lesions in Children: Institutional Experience at Subharti Dental College and Hospital.

Authors:  Preetika Chandna; Nikhil Srivastava; Vishal Bansal; Vijay Wadhwan; Prajesh Dubey
Journal:  Indian J Med Paediatr Oncol       Date:  2017 Oct-Dec
  7 in total

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